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Specialty: Transplant Surgery
Procedure: Heart Transplant

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Total 339 results found since Jan 2013.

Thromboelastography/Platelet Mapping® and Aspirin: Is There Evidence of a Meaningful Dose-Response Relationship in Children Supported With the Berlin Heart EXCOR Ventricular Assist Device?
Thromboelastography with Platelet Mapping® (TEG/PM) is widely used to adjust the dose of Aspirin (ASA) for children supported with the Berlin Heart EXCOR Pediatric Ventricular Assist Device (VAD). The use of TEG/PM is controversial in part because stroke remains a common occurrence and TEG/PM has never been validated for this purpose. We sought to determine whether there is a meaningful correlation between the dose of ASA and the TEG/PM ‘percent arachadonic acid (%AA) inhibition’ value in children supported with the EXCOR.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: L.J. May, C. Lo, T.M. Tesoro, J.L. Zehnder, S. Chen, J. Lee, M. Desai, D.B. McElhinney, D.N. Rosenthal, K. Maeda, C.S. Almond Source Type: research

Temporal Differences in Adverse Event Rates in Patients Bridged With the HeartWare Left Ventricular Assist Device
Left ventricular assist devices (LVAD) have significantly improved survival and quality of life in patients with advanced heart failure. However, these devices are associated with significant adverse events (AEs), particularly bleeding, infection, stroke and right heart failure. We sought to evaluate temporal differences in AE rates in patients bridged to transplantation.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: S. Maltais, K.D. Aaronson, J.J. Teuteberg, M.S. Slaughter, S.S. Najjar, V. Jeevanandam, D.T. Pham, E.C. McGee, K. Najarian, R.L. Kormos Source Type: research

Fortuity or Causality in Minimally Invasive LVAD Implantation: Relation Between Outflow Graft Height of Implantation Along the Ascending Aorta and Cerebral Ischemic Events
To evaluate whether the site of implantation of the outflow-graft on the ascending aorta is related to the incidence of cerebral ischemic stroke events in patients undergoing minimally-invasive-LVAD-implantation.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: J. Bejko, T. Bottio, G. Bortolussi, M. Gallo, R. Bianco, V. Tarzia, A. Guariento, G. Gerosa Source Type: research

Stroke Subtype Impacts Outcomes and Transplant Eligibility in CF-LVADS
We present a large single center experience on stroke outcome and transplant eligibility by stroke subtype in CF-LVAD pts.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: J.Z. Willey, M. Gavalas, A. Levin, A. Breskin, V.K. Topkara, M. Yuzefpolskaya, K. Orlanes, M.R. Torres, M. Tiburcio, K. Ross, R.A. Garan, K. Wong, U.P. Jorde, D.M. Mancini, K. Takeda, H. Takayama, Y. Naka, P.C. Colombo Source Type: research

Percutaneous Driveline Infection Does Not Increase Subsequent Risk of Stroke and Pump Thrombus During Support With a Left Ventricular Assist Device
Percutaneous driveline infections (DLI) pose significant risk in patients supported with a left ventricular assist device (LVAD). While INTERMACS data suggests increased incidence of thromboembolic complications in close proximity following DLI, no study has specifically examined this association in a time-dependent manner and analyzed risk of subsequent events. We reviewed the Mechanical Circulatory Support (MCS) Research Network registry.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: J. Van Meeteren, S. Maltais, S. Dunlay, N. Haglund, M.E. Davis, F.D. Pagani, K. Aaronson, J. Cowger, P. Shah, J.M. Stulak Source Type: research

Driveline Infection Is Not Associated With Increased Risk of Thrombotic Events in CF-LVAD Patients
It has been debated whether anti-thrombotic therapy should be adjusted in the setting of driveline infection (DLI) as infection may lead to a pro-inflammatory state associated with platelet activation and increased risk of thrombotic complications. The aim of this study was to examine the relationship of DLI and thrombotic complications, notably stroke and device thrombosis (DT), in patients with continuous-flow LVADs.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: J. Fried, B. Cagliostro, A. Levin, O. Wever-Pinzon, A.R. Garan, R. Te-Frey, K.O. Ronquillo, K. Takeda, H. Takayama, M. Yuzefpolskaya, D.M. Mancini, Y. Naka, P.C. Colombo, V. Topkara Source Type: research

“Framingham score, renal dysfunction and cardiovascular risk in liver transplant patients”
Conclusions: In our series, the FRS and eGFR at LT were able to predict the development of post‐LT CV events and poor outcome. This article is protected by copyright. All rights reserved.
Source: Liver Transplantation - March 30, 2015 Category: Transplant Surgery Authors: Tommaso Di Maira, Angel Rubin, Lorena Puchades, Victoria Aguilera, Carmen Vinaixa, Maria Garcia, Nicola De Maria, Erica Villa, Rafael Lopez‐Andujar, Fernando San Juan, Eva Montalva, Judith Perez, Martin Prieto, Marina Berenguer Tags: Original Articles Source Type: research

Biventricular failure with low pulmonary vascular resistance was managed by left ventricular assist device alone without right-sided mechanical support
Abstract How to manage preoperative right ventricular dysfunction (RVD) in heart failure patients without cardiogenic shock remains as a matter to be debated because implantable biventricular assist device treatment has not been established thus far. We here presented a patient with significant RVD indicated by low RV stroke work index (0.3 g/m) and RV dilatation as well as low pulmonary vascular resistance (PVR, 0.8 Wood Unit), who was managed by the introduction of pimobendan and sildenafil after the implantation of DuraHeart and tricuspid annuloplasty without right VAD, although his New York Heart Association ...
Source: Journal of Artificial Organs - March 13, 2015 Category: Transplant Surgery Source Type: research

First Implantation in Man of a New Magnetically Levitated Left Ventricular Assist Device (HeartMate III)
Outcomes of heart failure patients supported by a continuous flow left ventricular assist device (LVAD) have steadily improved over the past decade due in large part to better patient selection and management 1,2. Nevertheless, adverse events such as bleeding, infection, stroke and thrombus persist and limit the overall effectiveness of this therapy. Bleeding is the most common serious adverse event that results from the extensive surgery required for implantation and blood component damage due to shear forces in the small blood flow paths of current design axial-flow and centrifugal-flow pumps.
Source: The Journal of Heart and Lung Transplantation - March 7, 2015 Category: Transplant Surgery Authors: Jan D. Schmitto, Jasmin S. Hanke, Sebastian V. Rojas, Murat Avsar, Axel Haverich Source Type: research

Left Ventricular Assist Device Thrombosis In The Setting of Left Ventricular Recovery
Left ventricular assist device (LVAD) thrombosis has become increasingly recognized as a complication of mechanical circulatory support.1,2 Morbidity, including increased rate of stroke, and a marked increase in mortality are seen with LVAD thrombosis.1
Source: The Journal of Heart and Lung Transplantation - December 23, 2014 Category: Transplant Surgery Authors: Thomas E. Hurst, Nader Moazami, Randall C. Starling Source Type: research

Preexisting Atrial Fibrillation and Cardiac Complications After Liver Transplantation
Conclusion: Although patients with AF have a higher incidence of intraoperative cardiac events, a higher cardiovascular morbidity and a complicated postoperative course, this did not affect overall graft and patient survival. This article is protected by copyright. All rights reserved.
Source: Liver Transplantation - December 8, 2014 Category: Transplant Surgery Authors: Johannes Bargehr, Jorge F. Trejo‐Gutierrez, Tushar Patel, Barry Rosser, Jaime Aranda‐Michel, Maria L. Yataco, C. Burcin Taner Tags: Original Article Source Type: research

Blood pressure and stroke risk in left ventricular assist devices
Ischemic and hemorrhagic stroke are one of the most devastating outcomes arising from treatment of end-stage congestive heart failure with a left ventricular assist device (LVAD)1. Stroke after LVAD is associated with increased risk of mortality and is a leading cause of not qualifying for transplantation. The risk of stroke is one of many factors limiting more widespread adoption of this technology for end-stage heart failure. The risk factors for stroke in LVAD have been the subject of several studies, with recent infection2 and changes in anti-thrombotics being commonly found3.
Source: The Journal of Heart and Lung Transplantation - December 5, 2014 Category: Transplant Surgery Authors: Joshua Z. Willey Source Type: research

The use of a Berlin Heart EXCOR LVAD in a child receiving chemotherapy for Castleman's disease
We present the unique case of a pediatric patient who received chemotherapy for a diagnosis of CD, while mechanically supported with a Berlin EXCOR LVAD secondary to restrictive cardiomyopathy. A four‐yr‐old previously healthy male with restrictive cardiomyopathy required MCS after cardiac arrest but was diagnosed with multicentric CD, a non‐malignant lymphoproliferative disorder fueled by excessive IL‐6 production. Treatment with IL‐6 blockade (tocilizumab) every two wk and methylprednisolone had no effect on his lymph nodes or cardiac function while on temporary RotaFlow. A Berlin LVAD was placed for treatment...
Source: Pediatric Transplantation - December 1, 2014 Category: Transplant Surgery Authors: Tamara O. Thomas, Shanmuganathan Chandrakasan, Maureen O'Brien, John L. Jefferies, Thomas D. Ryan, Ivan Wilmot, Michael L. Baker, Peace C. Madueme, David Morales, Angela Lorts Tags: Case Report Source Type: research

High early cardiovascular mortality after liver transplantation
In conclusion, we provide the first multicenter prognostic model for the prediction of early post‐LT CVD death, the most common cause of early post‐LT mortality in the current transplant era. However, evaluations of additional CVD‐related variables not collected by the OPTN are needed in order to improve the model's accuracy and potential clinical utility. Liver Transpl, 2014. © 2014 AASLD.
Source: Liver Transplantation - October 24, 2014 Category: Transplant Surgery Authors: Lisa B. VanWagner, Brittany Lapin, Josh Levitsky, John T. Wilkins, Michael M. Abecassis, Anton I. Skaro, Donald M. Lloyd‐Jones Tags: Original Article Source Type: research

Systolic Blood Pressure on Discharge after Left Ventricular Assist Device Insertion is Associated with Subsequent Stroke
Stroke is a significant complication in patients supported with continuous-flow left ventricular assist devices (CF-LVAD) and hypertension (HTN) is a significant risk factor for stroke, but the association between blood pressure and stroke in LVAD patients is not well characterized.
Source: The Journal of Heart and Lung Transplantation - October 22, 2014 Category: Transplant Surgery Authors: Michael E. Nassif, Anjan Tibrewala, David S. Raymer, Adam Andruska, Eric Novak, Justin M. Vader, Akinobu Itoh, Scott C. Silvestry, Gregory A. Ewald, Shane J. LaRue Source Type: research