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Specialty: Radiology
Therapy: Radiation Therapy

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Total 27 results found since Jan 2013.

Risk of First and Recurrent Stroke in Childhood Cancer Survivors Treated With Cranial and Cervical Radiation Therapy
Conclusion: Cranial irradiation puts childhood cancer survivors at high risk of both first and recurrent stroke. Stroke prevention strategies for these survivors are needed.
Source: International Journal of Radiation Oncology * Biology * Physics - April 24, 2013 Category: Radiology Authors: Sabine Mueller, Katherine Sear, Nancy K. Hills, Nassim Chettout, Shervin Afghani, Erica Gastelum, Daphne Haas-Kogan, Heather J. Fullerton Tags: Pediatric Cancers Source Type: research

Radiation, Atherosclerotic Risk Factors, and Stroke Risk in Survivors of Pediatric Cancer: A Report From the Childhood Cancer Survivor Study
Conclusion: Young adult pediatric cancer survivors have an increased stroke risk that is associated with CRT in a dose-dependent manner. Atherosclerotic risk factors enhanced this risk and should be treated aggressively.
Source: International Journal of Radiation Oncology * Biology * Physics - May 15, 2013 Category: Radiology Authors: Sabine Mueller, Heather J. Fullerton, Kayla Stratton, Wendy Leisenring, Rita E. Weathers, Marilyn Stovall, Gregory T. Armstrong, Robert E. Goldsby, Roger J. Packer, Charles A. Sklar, Daniel C. Bowers, Leslie L. Robison, Kevin R. Krull Tags: Pediatric Cancers Source Type: research

Doses to Carotid Arteries After Modern Radiation Therapy for Hodgkin Lymphoma: Is Stroke Still a Late Effect of Treatment?
Conclusions: INRT reduces the dose delivered to the carotid arteries and corresponding estimated risk of stroke for HL survivors. Even for the subset of patients with lymphoma close to the carotid arteries, the estimated risk is low.
Source: International Journal of Radiation Oncology * Biology * Physics - August 2, 2013 Category: Radiology Authors: Maja V. Maraldo, Patrick Brodin, Marianne C. Aznar, Ivan R. Vogelius, Per Munck af Rosenschöld, Peter M. Petersen, Lena Specht Tags: Lymphomas Source Type: research

Stroke-Like Migraine Attacks after Radiation Therapy (SMART) Syndrome Is Not Always Completely Reversible: A Case Series FELLOWS' JOURNAL CLUB
SUMMARY: We retrospectively reviewed clinical and imaging findings in 11 patients with stroke-like migraine attacks after radiation therapy (SMART) syndrome to better understand this disorder previously thought to be reversible. Six men and 5 women had complex bouts of neurologic impairment beginning, on average, 20 years after cerebral irradiation. All had characteristic, unilateral gyriform enhancement on MR imaging that developed within 2–7 days and typically resolved in 2–5 weeks. Unlike prior reports, 45% had incomplete neurologic recovery manifesting as dysphasia, cognitive impairment, or hemiparesis. The...
Source: American Journal of Neuroradiology - December 13, 2013 Category: Radiology Authors: Black, D. F., Morris, J. M., Lindell, E. P., Krecke, K. N., Worrell, G. A., Bartleson, J. D., Lachance, D. H. Tags: FELLOWS ' JOURNAL CLUB Source Type: research

Risk of Symptomatic Stroke After Radiation Therapy for Childhood Cancer: A Long-Term Follow-Up Cohort Analysis
Long-term childhood cancer survivors are at high risk of late adverse effects, including stroke. We aimed to determine the cumulative incidence of clinically validated symptomatic stroke (transient ischemic attack [TIA], cerebral infarction, and intracerebral hemorrhage [ICH]) and to quantify dose-effect relationships for cranial radiation therapy (CRT) and supradiaphragmatic radiation therapy (SDRT).
Source: International Journal of Radiation Oncology * Biology * Physics - April 6, 2016 Category: Radiology Authors: Irma W.E.M. van Dijk, Helena J.H. van der Pal, Rob M. van Os, Yvo B.W.E.M. Roos, Elske Sieswerda, Elvira C. van Dalen, Cécile M. Ronckers, Foppe Oldenburger, Flora E. van Leeuwen, Huib N. Caron, Caro C.E. Koning, Leontien C.M. Kremer Tags: Clinical Investigation Source Type: research

Susceptibility-weighted imaging in stroke-like migraine attacks after radiation therapy syndrome
Conclusion These preliminary findings suggest that SWI may help identify SMART syndrome or at least help discriminate it from other disorders, by the findings of numerous susceptibility hypointensities on SWI likely representing RICHs, gyriform enhancement on T1WI, and postsurgical findings or appropriate clinical history.
Source: Neuroradiology - August 5, 2015 Category: Radiology Source Type: research

Stroke After Radiation Therapy for Head and Neck Cancer: What Is the Risk?
A retrospective population-based cohort study was conducted to determine the risk of ischemic stroke with respect to time, associated with curative radiation therapy in head and neck squamous cell carcinomas (HNSCC).
Source: International Journal of Radiation Oncology * Biology * Physics - July 15, 2016 Category: Radiology Authors: Erin Arthurs, Timothy P. Hanna, Khaled Zaza, Yingwei Peng, Stephen F. Hall Tags: Clinical Investigation Source Type: research

Atypical imaging findings of presumed stroke-like migraine attacks after radiation therapy syndrome in the brainstem
AbstractThe authors present an atypical case of presumed stroke-like migraine attacks after radiation therapy (SMART) syndrome in the brainstem. A 29-year-old male, who had been treated with resection and subsequent craniospinal radiation for posterior fossa medulloblastoma 21 years before, presented with subacute progressive left hemiparesis evolving over 4 days. Hematological findings, cerebrospinal fluid (CSF), and electroencephalogram (EEG) were unremarkable. Magnetic resonance imaging (MRI) showed a round area of hyperintense FLAIR signal centered within the pons associated with central restricted diffusion, periphera...
Source: Neuroradiology - March 11, 2021 Category: Radiology Source Type: research

Prognostic Factors of Stroke-Like Migraine Attacks after Radiation Therapy (SMART) Syndrome ADULT BRAIN
CONCLUSIONS: Age, use of steroid treatment at the diagnosis of SMART syndrome, and MR imaging findings of abnormal susceptibility signal, restricted diffusion, and subcortical WM change in the acute SMART region can be prognostic factors in SMART syndrome.
Source: American Journal of Neuroradiology - March 10, 2022 Category: Radiology Authors: Ota, Y., Leung, D., Lin, E., Liao, E., Kurokawa, R., Kurokawa, M., Baba, A., Yokota, H., Bathla, G., Moritani, T., Srinivasan, A., Capizzano, A. A. Tags: ADULT BRAIN Source Type: research

In Regard to Arthurs et  al
To the Editor: Arthurs et  al (1) present another large database analysis, this one focusing on the risk of stroke for head and neck cancer patients receiving radiation therapy. These analyses allow the use of relatively large numbers to obtain “significant” P values. Their finding of a 46% to 70% higher cause-specific hazard of stroke with radiation therapy compared with the “control” of surgery alone seems very compelling.
Source: International Journal of Radiation Oncology * Biology * Physics - January 4, 2017 Category: Radiology Authors: Pierre Blanchard, Adam S. Garden Tags: Comment Source Type: research

Comprehensive Update and Review of Clinical and Imaging Features of SMART Syndrome ADULT BRAIN
SUMMARY: Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a delayed complication of cranial irradiation, with subacute onset of stroke-like symptoms including seizures, visual disturbance, speech impairment, unilateral hemianopsia, facial droop, and aphasia, often associated with migraine-type headache. The diagnostic criteria were initially proposed in 2006. However, the diagnosis of SMART syndrome is challenging because clinical symptoms and imaging features of SMART syndrome are indeterminate and overlap with tumor recurrence and other neurologic diseases, which may result in inappropriate clinic...
Source: American Journal of Neuroradiology - June 8, 2023 Category: Radiology Authors: Ota, Y., Liao, E., Shah, G., Srinivasan, A., Capizzano, A. A. Tags: ADULT BRAIN Source Type: research

Risk of Cerebrovascular Events in Elderly Patients After Radiation Therapy Versus Surgery for Early-Stage Glottic Cancer
Purpose: Comprehensive neck radiation therapy (RT) has been shown to increase cerebrovascular disease (CVD) risk in advanced-stage head-and-neck cancer. We assessed whether more limited neck RT used for early-stage (T1-T2 N0) glottic cancer is associated with increased CVD risk, using the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database.Methods and Materials: We identified patients ≥66 years of age with early-stage glottic laryngeal cancer from SEER diagnosed from 1992 to 2007. Patients treated with combined surgery and RT were excluded. Medicare CPT codes for carotid interventions, Medicare IC...
Source: International Journal of Radiation Oncology * Biology * Physics - July 30, 2013 Category: Radiology Authors: Julian C. Hong, Tim J. Kruser, Vinai Gondi, Pranshu Mohindra, Donald M. Cannon, Paul M. Harari, Søren M. Bentzen Tags: Head and Neck Cancers Source Type: research