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Improvement of memory impairments in poststroke patients by hyperbaric oxygen therapy.
Objective: Several recent studies have shown that hyperbaric oxygen (HBO₂) therapy carry cognitive and motor therapeutic effects for patients with acquired brain injuries. The goal of this study was to address the specific effects of HBO₂ on memory impairments after stroke at late chronic stages. Method: A retrospective analysis was conducted on data of 91 stroke patients 18 years or older (mean age ∼60 years) who had either ischemic or hemorrhagic stroke 3–180 months before HBO₂ therapy (M = 30–35 months). The HBO₂ protocol included 40 to 60 daily sessions, 5 days per week, 90 min each, 100% oxygen at 2ATA, ...
Source: Neuropsychology - November 10, 2014 Category: Neurology Authors: Boussi-Gross, Rahav; Golan, Haim; Volkov, Olga; Bechor, Yair; Hoofien, Dan; Schnaider Beeri, Michal; Ben-Jacob, Eshel; Efrati, Shai Source Type: research

Neurobiological insight into hyperbaric hyperoxia
ConclusionsThe present study firstly confirmed the rCBF distribution increase during HBO in sensory‐motor and visual cortices and it showed for the first time a higher perfusion tracer distribution in areas encompassed in dorsal attention system and in default mode network. These findings unfold both the externally directed cognition performance improvement related to the HBO and the internally directed cognition states during resting state conditions, suggesting possible beneficial effects in TBI and stroke patients.This article is protected by copyright. All rights reserved.
Source: Acta Physiologica - May 21, 2013 Category: Physiology Authors: Alessandro Micarelli, Hans Jacobsson, Stig A Larsson, Cathrine Jonsson, Marco Pagani Tags: Regular Paper Source Type: research

Brain perfusion SPECT provides new insight on neurobiological effects of hyperbaric hyperoxia
This article is protected by copyright. All rights reserved.
Source: Acta Physiologica - June 25, 2013 Category: Physiology Authors: Silvia Morbelli, Dario Arnaldi Tags: Editorial Source Type: research

Combined Treatment of Methylprednisolone Pulse and Memantine Hydrochloride Prompts Recovery from Neurological Dysfunction and Cerebral Hypoperfusion in Carbon Monoxide Poisoning: A Case Report
A 49-year-old healthy man developed sudden unconsciousness under inadequate ventilation. Blood gas analysis showed carboxyhemoglobin of 7.3%. After normobaric oxygen therapy, he recovered completely 7 days later. At 3 weeks after carbon monoxide (CO) exposures, memory and gait disturbances appeared. Neurological examination revealed Mini-Mental State Examination (MMSE) score of 5 of 30 points, leg hyper-reflexia with Babinski signs, and Parkinsonism. Brain fluid-attenuated inversion recovery imaging disclosed symmetric hypointense lesions in the thalamus and the globus pallidus, and hyperintense lesions in the cerebral w...
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2013 Category: Neurology Authors: Konosuke Iwamoto, Ken Ikeda, Sunao Mizumura, Kazuhiro Tachiki, Masaru Yanagihashi, Yasuo Iwasaki Tags: Case Reports Source Type: research

Hyperbaric oxygen can induce neuroplasticity and improve cognitive functions of patients suffering from anoxic brain damage.
CONCLUSIONS: Although further research is needed, the results demonstrate the beneficial effects of HBO2 on CCI in patients after cardiac arrest, even months to years after the acute event. PMID: 26409406 [PubMed - in process]
Source: Restorative Neurology and Neuroscience - January 25, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research