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Total 1942 results found since Jan 2013.

Predicting brain atrophy from resting-state functional connectivity and structural connectivity in ischemic stroke (P5.297)
Conclusions:Resting-state functional connectivity with the lesion location can predict atrophy of remote brain regions after ischemic stroke, independent of structural white-matter connectivity.Study Supported by: M.D.F. was supported by the National Institutes of Health (R21 MH099196, K23 NS083741), Dystonia Medical Research Foundation, National Parkinson’s Foundation, and NFL Players Association. A.J. was supported by a Postdoctoral Fellowship from the Natural Sciences and Engineering Research Council of Canada (NSERC PDF 454617). A.D.B. was supported by 4K12HD027748-24.Disclosure: Dr. Jannati has nothing to disclo...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Jannati, A., Boes, A. D., Horn, A., Pascual-Leone, A., Kuceyeski, A., Fox, M. D. Tags: Stroke Recovery and Rehabilitation Source Type: research

Thrombolysis for acute ischemic stroke in South Africa
ConclusionsOur findings indicate that the use of thrombolysis in routine clinical practice in a South African setting has similar safety and early efficacy outcomes to developed and other developing countries.
Source: International Journal of Stroke - May 22, 2013 Category: Neurology Authors: Alan Bryer, Sean Wasserman Tags: Short Report Source Type: research

Incidence of Venous Thromboembolism in the Wake of the Clots in Legs Or sTockings after Stroke (CLOTS) Study Brief Reports
Conclusions— Discontinuation of compressive stockings did not increase venous thromboembolism incidence. There was a trend toward more deep vein thrombosis and fewer PEs after CLOTS, which might be because of increased clinical vigilance in the diagnosis of deep vein thrombosis, but a chance variation cannot be excluded.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Jain, P., Ward, E., Nevatte, T., Roffe, C. Tags: Deep vein thrombosis Brief Reports Source Type: research

Alberta Stroke Program Early Computed Tomography Score to Select Patients for Endovascular Treatment: Interventional Management of Stroke (IMS)-III Trial Clinical Sciences
Conclusions— ASPECTS is a strong predictor of outcome and a predictor of reperfusion. ASPECTS did not identify a subpopulation of subjects that particularly benefitted from endovascular therapy immediately after routine intravenous tPA. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00359424.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Hill, M. D., Demchuk, A. M., Goyal, M., Jovin, T. G., Foster, L. D., Tomsick, T. A., von Kummer, R., Yeatts, S. D., Palesch, Y. Y., Broderick, J. P., for the IMS3 Investigators Tags: Angiography, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis, Angioplasty and Stenting Clinical Sciences Source Type: research

Evaluating Middle Cerebral Artery Atherosclerotic Lesions in Acute Ischemic Stroke Using Magnetic Resonance T1-weighted 3-Dimensional Vessel Wall Imaging
Background: Atherosclerotic lesions in intracranial arteries are a leading cause of ischemic stroke. Magnetic resonance angiography (MRA) is often used to assess atherosclerotic changes by detecting luminal narrowing, whereas it cannot directly visualize atherosclerotic lesions. Here, we used a 3-dimensional vessel wall imaging (3D-VWI) technique to evaluate intracranial arterial wall changes in acute stroke.Methods: Eighteen consecutive patients with acute noncardioembolic stroke in the middle cerebral artery (MCA) territory who were prospectively examined with a 1.5-T magnetic resonance scanner were studied. T1-weighted ...
Source: Journal of Stroke and Cerebrovascular Diseases - July 22, 2013 Category: Neurology Authors: Tatsunori Natori, Makoto Sasaki, Mitsuharu Miyoshi, Hideki Ohba, Noriyuki Katsura, Mao Yamaguchi, Shinsuke Narumi, Hiroyuki Kabasawa, Kohsuke Kudo, Kenji Ito, Yasuo Terayama Tags: Original Articles Source Type: research

Six-Minute Magnetic Resonance Imaging Protocol for Evaluation of Acute Ischemic Stroke: Pushing the Boundaries Clinical Sciences
Conclusions— A 6-minute multimodal MR protocol with good diagnostic quality is feasible for the evaluation of patients with acute ischemic stroke and can result in significant reduction in scan time rivaling that of the multimodal computed tomographic protocol.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Nael, K., Khan, R., Choudhary, G., Meshksar, A., Villablanca, P., Tay, J., Drake, K., Coull, B. M., Kidwell, C. S. Tags: CT and MRI, Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Atrial Fibrillation and Cognitive Decline-The Role of Subclinical Cerebral Infarcts: The Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— The association of incident AF with cognitive decline in stroke-free individuals can be explained by the presence or development of SCIs, raising the possibility of anticoagulation as a strategy to prevent cognitive decline in AF.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Chen, L. Y., Lopez, F. L., Gottesman, R. F., Huxley, R. R., Agarwal, S. K., Loehr, L., Mosley, T., Alonso, A. Tags: Cerebrovascular disease/stroke, Arrhythmias, clinical electrophysiology, drugs, Computerized tomography and Magnetic Resonance Imaging, Epidemiology Clinical Sciences Source Type: research

Determinants of White Matter Hyperintensity Burden Differ at the Extremes of Ages of Ischemic Stroke Onset
Age is a well-known risk factor for both stroke and increased burden of white matter hyperintensity (WMH), as detected on magnetic resonance imaging (MRI) scans. However, in patients diagnosed with ischemic stroke (IS), WMH volume (WMHv) varies significantly across age groups. We sought to examine the determinants of WMH burden across the ages of stroke onset with the goal to uncover potential age-specific stroke prevention targets.
Source: Journal of Stroke and Cerebrovascular Diseases - January 6, 2015 Category: Neurology Authors: Cathy R. Zhang, Lisa Cloonan, Kaitlin M. Fitzpatrick, Allison S. Kanakis, Alison M. Ayres, Karen L. Furie, Jonathan Rosand, Natalia S. Rost Source Type: research

Comparison of the 2 Most Popular Deconvolution Techniques for the Detection of Penumbral Flow in Acute Stroke Clinical Sciences
Conclusions— Block-circulant single value decomposition seems only significantly beneficial for mean transit time maps in (sub)acute stroke. Tmax is likely the most stable deconvolved parameter for the detection of tissue-at-risk using DSC-MRI.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Zaro-Weber, O., Livne, M., Martin, S. Z., von Samson-Himmelstjerna, F. C., Moeller-Hartmann, W., Schuster, A., Brunecker, P., Heiss, W.-D., Sobesky, J., Madai, V. I. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, PET and SPECT Clinical Sciences Source Type: research

Ultra-acute CT perfusion imaging: A stroke in the scanner
A stroke patient with a mild right hemiparesis (NIH Stroke Scale score 4) underwent dual-slab CT perfusion (CTP). In the midst of acquiring the lower CTP slab, she became aphasic and developed a dense right hemiparesis (NIH Stroke Scale score 17). Reconstruction of the CTP into a dynamic CT angiogram demonstrates fragmentation of an internal carotid artery thrombus at the time of clinical worsening (figure 1; video on the Neurology® Web site at Neurology.org). The upper CTP slab, acquired 2 minutes later, provides the earliest known view of the hemodynamics of ischemic stroke in humans. It demonstrates total absence of...
Source: Neurology - November 9, 2015 Category: Neurology Authors: Christensen, S., Obi, C., Albers, G., Lansberg, M. Tags: CT, All Cerebrovascular disease/Stroke, Embolism, Infarction VIDEO NEUROIMAGES Source Type: research

Intra-Arterial Therapy and Post-Treatment Infarct Volumes: Insights From the ESCAPE Randomized Controlled Trial Clinical Sciences
Conclusions— These results support the primary results of the ESCAPE trial and show that the biological underpinning of the success of endovascular therapy is a reduction in infarct volume. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01778335.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Al-Ajlan, F. S., Goyal, M., Demchuk, A. M., Minhas, P., Sabiq, F., Assis, Z., Willinsky, R., Montanera, W. J., Rempel, J. L., Shuaib, A., Thornton, J., Williams, D., Roy, D., Poppe, A. Y., Jovin, T. G., Sapkota, B. L., Baxter, B. W., Krings, T., Silver, F Tags: Imaging, Quality and Outcomes, Ischemic Stroke Clinical Sciences Source Type: research

Neuroimaging Markers of Cognitive Outcome in Children with Perinatal Stroke (I2.002)
Conclusions: As seen in other studies, prognosis of cognitive outcome is difficult and there was no correlation between site of lesion and areas of intellectual deficit. However, there was some indication that loss of more cortical volume, or involvement of the DLPF cortex may be risk factors for intellectual impairment in childhood.Disclosure: Dr. Murias has nothing to disclose. Dr. Kirton has nothing to disclose. Dr. Tariq has nothing to disclose. Dr. Moir has nothing to disclose. Dr. Iaria has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Murias, K., Kirton, A., Tariq, S., Moir, A., Iaria, G. Tags: Stroke in the Elderly and Young: Challenges for the Next Decade Data Blitz Presentations Source Type: research

Neuroimaging Markers of Cognitive Outcome in Children with Perinatal Stroke (P3.256)
Conclusions: As seen in other studies, prognosis of cognitive outcome is difficult and there was no correlation between site of lesion and areas of intellectual deficit. However, there was some indication that loss of more cortical volume, or involvement of the DLPF cortex may be risk factors for intellectual impairment in childhood.Disclosure: Dr. Murias has nothing to disclose. Dr. Kirton has nothing to disclose. Dr. Tariq has nothing to disclose. Dr. Moir has nothing to disclose. Dr. Iaria has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Murias, K., Kirton, A., Tariq, S., Moir, A., Iaria, G. Tags: Child Neurology and Developmental Neurology: Epilepsy, Hypoxia, and Stroke Source Type: research

Multidisciplinar Team Ability to Decrease Door-To-Needle Time in Acute Ischemic Stroke - A Single Center Saudi Experience (P6.053)
Conclusions: Implementation of modified stroke code process utilizing quality improvement paradigm of PDSA cycles have resulted in significant decrease in door-to-needle time for IV thrombolysis. Although, the target DTN of 60 minutes was not reached, the trend is favorable with improved outcomes. Disclosure: Partly presented at 5th Annual KAIMRC Forum, September, 2014, Jeddah, Saudi ArabiaDisclosure: Dr. Khatri has nothing to disclose. Dr. Khathaami has nothing to disclose. Dr. Alhamouieh has nothing to disclose. Dr. Abulaban has nothing to disclose. Dr. Scriven has nothing to disclose. Dr. Tarawneh has nothing to disclos...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Khatri, I., Khathaami, A., Alhamouieh, O., Abulaban, A., Scriven, S., Tarawneh, M., Alrasheed, D., AlSomali, S., Catangui, E., Manalili, C., Ghadalla, A., Alanizi, A., Kojan, S. Tags: Prehospital Stroke Care and Uses of NIHSS Source Type: research

Evolutional Characterization of Photochemically Induced Stroke in Rats: a Multimodality Imaging and Molecular Biological Study
In conclusion, these characterizations may be highly beneficial to the development of therapeutic strategies for ischemi c stroke.
Source: Translational Stroke Research - November 30, 2016 Category: Neurology Source Type: research