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Specialty: Molecular Biology
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Total 1564 results found since Jan 2013.
Mechanisms of Action of a Herbal Formula Huangqi Guizhi Wuwu Tang for the Management of Post-Stroke Related Numbness and Weakness: A Computational Molecular Docking Study
In conclusion, HGWT may provide therapeutic benefits through strong interactions between herbal compounds and target proteins of PDE5A and ESR1. Further experimental studies are needed to unequivocally support this result which can be valuable to increase the quality of life of post-stroke patients. Keywords Herbal medicine, Complementary and alternative medicine, Natural product, Post-stroke, Computational analysis.PMID:35369720 | DOI:10.1177/2515690X221082989
Source: Molecular Medicine - April 4, 2022 Category: Molecular Biology Authors: Sanghyun Lee Andrew Hung Hong Li Angela Wei Hong Yang Source Type: research
Tug1 Acts on ERK12 Signaling Pathway to Aggravate Neuronal Damage after Acute Ischemic Stroke
This study mainly considers the role of lncRNA tug 1 on the ERK 12 signaling pathway to enhance neuronal damage after acute ischemic stroke. In the experiment, the middle cerebral artery occlusion (MCAO) model was constructed using the thread embolization method. The real-time quantitative RT-CR method was used to detect the relative transcriptional activity of TG1, GAS5 and SM22a genes in tissues. The relative expression level of SM22a protein in tissues was detected by the immune-histochemical method. Twenty-four hours after cerebral infarction, the nerve function, cerebral infarction area and ERK1/2 protein expression l...
Source: Cellular and Molecular Biology - July 9, 2022 Category: Molecular Biology Authors: Xiaojie Chen Yuduan Xie Chunling Liang Dawei Yang Xiaotao Li Jie Yu Source Type: research
The effect of nursing and rehabilitation measures on quality of life and expression of Bax/Bcl2 genes in patients with stroke
Cell Mol Biol (Noisy-le-grand). 2022 May 31;68(5):111-116. doi: 10.14715/cmb/2022.68.5.15.ABSTRACTStroke is the leading cause of neurological problems and the third leading cause of death globally, leading to various neurological defects. Due to the importance of applying nursing and rehabilitation measures to reduce complications in these patients, a study was conducted to determine the effect of nursing and rehabilitation measures on the quality of life of patients with stroke. This two-stage experimental study (before and after) was performed on 20 patients with stroke admitted to the internal medicine department. Patie...
Source: Mol Biol Cell - August 27, 2022 Category: Molecular Biology Authors: Beibei Zhang Jing Li Jianyong Chen Source Type: research
Bioinformatic Prediction of Depression-Related Signaling Pathways Regulated by miR-146a in Peripheral Blood of Patients with Post-Stroke Depression
In conclusion, the expression level of miR-146a-5p was abnormally increased in PSD patients, and it could be taken as a candidate marker for the diagnosis of PSD. miR-146a-5p could affect PSD through signaling pathways of TLRs, neurotrophic factors, and NF-κB.PMID:36227679 | DOI:10.14715/cmb/2022.68.6.7
Source: Mol Biol Cell - October 13, 2022 Category: Molecular Biology Authors: Zhimin Chen Na Wang Risu Na Haiyan Yu Dan Sui Bing Cui Lihua Wang Source Type: research
