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Chronic blood transfusion for primary and secondary stroke prevention in Nigerian children with sickle cell disease: A 5‐year appraisal
ConclusionHigh economic costs, unavailability of blood, need to regularly seek for blood donors, cultural beliefs, and high frequency of transfusion reactions are major challenges to a successful CBT program in Nigeria. There is a need for government subsidy on blood transfusions and improved efforts towards provision of safe and affordable blood. Pediatr Blood Cancer. © 2013 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - August 19, 2013 Category: Cancer & Oncology Authors: I.A. Lagunju, B.J. Brown, O.O. Sodeinde Tags: Research Article Source Type: research

Primary stroke prevention in Nigerian children with sickle cell disease (SPIN): Challenges of conducting a feasibility trial
ConclusionA hydroxyurea trial (NCT01801423) for children with SCD is feasible in sub‐Saharan Africa; however, extensive training and resources are needed to build a global patient oriented multi‐disciplinary research team with a common purpose. Pediatr Blood Cancer. © 2014 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - November 14, 2014 Category: Cancer & Oncology Authors: Najibah A. Galadanci, Shehu U. Abdullahi, Musa A. Tabari, Shehi Abubakar, Raymond Belonwu, Auwal Salihu, Kathleen Neville, Fenella Kirkham, Baba Inusa, Yu Shyr, Sharon Phillips, Adetola A. Kassim, Lori C. Jordan, Muktar H. Aliyu, Brittany V. Covert, Micha Tags: Research Article Source Type: research

Neurovascular Manifestations of Iron-Deficient Anemia: Narrative Review and Practical Reflections through a Teaching Case
Conclusions: IDA is a common but treatable condition that, independently or synergically, may increase the risk of thrombotic events. The diagnostic and therapeutic approach has not yet been defined, and each case should be individually addressed in a pragmatic clinical road map.PMID:36294407 | DOI:10.3390/jcm11206088
Source: Clinical Lung Cancer - October 27, 2022 Category: Cancer & Oncology Authors: Marialuisa Zedde Giacomo Portaro Laura Ferri Francesco Cavallieri Manuela Napoli Claudio Moratti Fabrizio Piazza Franco Valzania Rosario Pascarella Source Type: research

Hydroxyurea lowers transcranial Doppler flow velocities in children with sickle cell anaemia in a Nigerian cohort
ConclusionHU appears to significantly reduce TCD velocities in Nigerian children with SCA and elevated velocities ≥170 cm/sec with beneficial effect on the haematological profile. HU may provide an effective approach to primary stroke prevention, particularly in Africa. Pediatr Blood Cancer © 2015 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - April 2, 2015 Category: Cancer & Oncology Authors: IkeOluwa Lagunju, Biobele J. Brown, Olugbemiro Sodeinde Tags: Research Article Source Type: research

Risk Factors and In-Hospital Outcomes of Perioperative Atrial Fibrillation for Patients with Cancer: A Meta-Analysis
CONCLUSIONS: For patients with cancer, POAF is associated with an increased burden of comorbidities and worse outcomes.PMID:36273057 | DOI:10.1245/s10434-022-12690-y
Source: Ann Oncol - October 22, 2022 Category: Cancer & Oncology Authors: Keiko Inoue Kazuko Tajiri DongZhu Xu Nobuyuki Murakoshi Masaki Ieda Source Type: research

Age‐related treatment patterns in sickle cell disease patients and the associated sickle cell complications and healthcare costs
ConclusionsPatients transitioning to adult care received less transfusions and hydroxyurea, less ICT when eligible for chelation therapy, had higher healthcare costs and suffered from more frequent SCD related complications than pediatric patients. These findings highlight the changes in treatment patterns corresponding to transition to adult care. Pediatr Blood Cancer © 2013 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - January 17, 2013 Category: Cancer & Oncology Authors: Morey A. Blinder, Francis Vekeman, Medha Sasane, Alex Trahey, Carole Paley, Mei Sheng Duh Tags: Research Article Source Type: research

Reduction in Overt and Silent Stroke Recurrence Rate Following Cerebral Revascularization Surgery in Children with Sickle Cell Disease and Severe Cerebral Vasculopathy
ConclusionsThe rate of overt and silent infarct recurrence was significantly lower following indirect cerebral revascularization. A prospective study of cerebral revascularization in children with SCD is needed.
Source: Pediatric Blood and Cancer - April 21, 2016 Category: Cancer & Oncology Authors: Erin M. Hall, Jeffrey Leonard, Jodi L. Smith, Kristin P. Guilliams, Michael Binkley, Robert J. Fallon, Monica L. Hulbert Tags: Research Article Source Type: research

The effects of neoadjuvant therapy on morbidity and mortality of esophagectomy for esophageal cancer: American college of surgeons national surgical quality improvement program (ACS –NSQIP) 2005–2012
ConclusionsWe conclude that neoadjuvant therapy followed by esophagectomy for esophageal cancer does not have a negative impact on 30‐day mortality. Neoadjuvant therapy is associated with increased odds of PE. J. Surg. Oncol. © 2016 Wiley Periodicals, Inc.
Source: Journal of Surgical Oncology - November 3, 2016 Category: Cancer & Oncology Authors: Michel J. Sabra, Carmen Smotherman, Dale F. Kraemer, Michael S. Nussbaum, Joseph J. Tepas, Ziad T. Awad Tags: Research Article Source Type: research