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Vaccination-Associated Myocarditis and Myocardial Injury
Circ Res. 2023 May 12;132(10):1338-1357. doi: 10.1161/CIRCRESAHA.122.321881. Epub 2023 May 11.ABSTRACTSARS-CoV-2 vaccine-associated myocarditis/myocardial injury should be evaluated in the contexts of COVID-19 infection, other types of viral myocarditis, and other vaccine-associated cardiac disorders. COVID-19 vaccine-associated myocardial injury can be caused by an inflammatory immune cell infiltrate, but other etiologies such as microvascular thrombosis are also possible. The clinical diagnosis is typically based on symptoms and cardiac magnetic resonance imaging. Endomyocardial biopsy is confirmatory for myocarditis, bu...
Source: Circulation Research - May 11, 2023 Category: Cardiology Authors: Natasha L Altman Amber A Berning Sarah C Mann Robert A Quaife Edward A Gill Scott R Auerbach Thomas B Campbell Michael R Bristow Source Type: research

Multiple encephalopathy syndrome: a case of a novel radiological subtype of acute encephalopathy in childhood
CONCLUSIONS: To the best of our knowledge, these significant MRI findings associated with acute encephalopathy have never been reported. Thus, herein, we propose the new term radiological "multiple encephalopathy syndrome (MES)" based on our case of acute encephalopathy in childhood.PMID:36066146 | DOI:10.26355/eurrev_202208_29509
Source: Pharmacological Reviews - September 6, 2022 Category: Drugs & Pharmacology Authors: Y Fujita G Imataka H Sakuma J-I Takanashi S Yoshihara Source Type: research

Acute necrotizing encephalopathy
We present the case of a 29-year-old previously healthy man with an imaging and clinical diagnosis of influenza B virus infection and sudden decline in mental status. Magnetic resonance imaging showed multifocal areas of abnormal T2 FLAIR signal and restricted diffusion without significant enhancement, with negative mircobiological studies of cerebrospinal fluid. The patient died despite multiple treatments including an antiviral, steroids, and intravenous immunoglobulin. Due to ANE's more common presentation during childhood, this case report represents one of the few available publications in the adult population.PMID:35...
Source: Baylor University Medical Center Proceedings - August 22, 2022 Category: Universities & Medical Training Authors: Roberto Hernandez Richi Ota Yasier Medina Yaimara Hernandez Parunyou Julayanont Henrik Wilms Source Type: research

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