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Assessment of Disease Burden and Immunization Rates for Vaccine-Preventable Diseases in People Living with HIV: The Korea HIV/AIDS Cohort Study
CONCLUSION: The burden of vaccine-preventable diseases was quite high in HIV-infected patients. Nadir CD4 T-cell counts, peak HIV viral loads, and the number of ART regimen change are significant factors related to vaccination. Considering the low vaccination rates for VPDs, there was a discordance between experts' opinions and real clinical practice in the medical field.PMID:37674339 | DOI:10.3947/ic.2023.0045
Source: Herpes - September 7, 2023 Category: Infectious Diseases Authors: Hye Seong Yunsu Choi Kyoung Hwan Ahn Jun Yong Choi Shin-Woo Kim Sang Il Kim Mee-Kyung Kee Bo Youl Choi Boyoung Park Hak Jun Hyun Jin Gu Yoon Ji Yun Noh Hee Jin Cheong Woo Joo Kim Joon Young Song Source Type: research

Chronic medical conditions associated with invasive pneumococcal diseases in inpatients in teaching hospitals in S ão Paulo city: Estimating antimicrobial susceptibility and serotype-coverage of pneumococcal vaccines
CONCLUSION: Vaccine with expanded valence of serotypes is necessary to offer broad prevention to IPD. The present data contribute to pneumococcal vaccination public health policies for vulnerable patients, mainly those with comorbidity and the elderly.PMID:36758625 | DOI:10.1016/j.bjid.2023.102746
Source: Braz J Infect Dis - February 9, 2023 Category: Infectious Diseases Authors: Renato A Kfouri Maria-Cristina C Brandileone Marco Aur élio P Sáfadi Rosana Richtmann Alfredo E Gilio Flavia Rossi Thais Guimar ães Ana Luiza Bierrenbach Jos é C Moraes S ão Paulo Study Group for IPD Source Type: research

Application of vaccine response in the evaluation of patients with suspected B-cell immunodeficiency: Assessment of responses and challenges with interpretation
J Immunol Methods. 2022 Sep 3:113350. doi: 10.1016/j.jim.2022.113350. Online ahead of print.ABSTRACTDiagnostic vaccination is an integral component in the evaluation of patients suspected to have a B cell or humoral deficiency. Evaluation of antibody production in response to both protein- and polysaccharide-based vaccines aids in distinguishing between specific categories of humoral deficiency. Although assessment of pneumococcal polysaccharide responses is widely available and included in diagnostic guidelines, significant variability still exists in the measurement and interpretation of these responses. Interpretation c...
Source: Journal of Immunological Methods - September 6, 2022 Category: Allergy & Immunology Authors: Lisa K Peterson Source Type: research

The Virus Hunters Trying to Prevent the Next Pandemic
Nobody saw SARS-CoV-2 coming. In the early days of the pandemic, researchers were scrambling to collect samples from people who had mysteriously developed fevers, coughs, and breathing problems. Pretty soon, they realized that the disease-causing culprit was a new virus humans hadn’t seen before. And the world, lacking a coordinated global response, was unprepared. Some countries acted quickly to develop tests for the novel coronavirus, while others with fewer resources were left behind. With a virus oblivious to national borders, and with travel between countries and continents more common than it had been in previo...
Source: TIME: Health - August 1, 2022 Category: Consumer Health News Authors: Alice Park and Video by Andrew D. Johnson Tags: Uncategorized Disease Frontiers of Medicine 2022 healthscienceclimate Source Type: news

Pneumococcal vaccination coverage among adults newly diagnosed with underlying medical conditions and regional variation in the U.S
CONCLUSION: Pneumococcal vaccination remains low and most adults with underlying conditions are unvaccinated. Insights into factors associated with vaccination, including regional variability, can help to increase pneumococcal vaccination.PMID:35803847 | DOI:10.1016/j.vaccine.2022.06.068
Source: Vaccine - July 8, 2022 Category: Allergy & Immunology Authors: Anna Ostropolets Linda Shoener Dunham Kelly D Johnson Junqing Liu Source Type: research

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