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Infectious Disease: Tuberculosis

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Prosthetic joint infection of the hip and knee due to < em > Mycobacterium species < /em > : A systematic review
CONCLUSION: At least 17 Mycobacterium sp can be responsible for hip/knee PJI. Although M. tuberculosis is the most common causal pathogen, NTM should be considered as an emerging cause of hip/knee PJI.PMID:35633748 | PMC:PMC9125004 | DOI:10.5312/wjo.v13.i5.503
Source: World Journal of Orthopaedics - May 31, 2022 Category: Orthopaedics Authors: Asep Santoso Krisna Yuarno Phatama Sholahuddin Rhatomy Nicolaas Cyrillus Budhiparama Source Type: research

TREMFYA ® (guselkumab) Real-World Data Analyses Show Greater Treatment Persistence Than IL-17s in Both Bio-naïve and Bio-experienced Patients Living With Moderate to Severe Plaque Psoriasis
SPRING HOUSE, PENNSYLVANIA, March 17, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data, showing that initiation of TREMFYA® (guselkumab) was associated with greater treatment persistencea compared to secukinumab or ixekizumab in bio-naïve and bio-experienced patientsb living with moderate to severe plaque psoriasis (PsO), based on pairwise analysesc of real-world data.[1],[2] Additionally, in a post-hoc analysis of Phase 3 VOYAGE 2 clinical trial results, TREMFYA demonstrated durable clinical efficacy, itch relief and quality-of-life improvements in patients living with scal...
Source: Johnson and Johnson - March 17, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Healthcare Update Satellite — 07-2-2014
Ve have vays of keeping you qviet. Halt den mund! Government-contracted security force who actually call themselves the “Brown Shirts” … threatens to arrest medical providers if they leak any information to media about all of the medical illnesses that are being seen at an illegal alien refugee camp in Lackland Air Force Base. By the way, this story is from FoxNews, so everyone should just ignore it until you or your family members sit next to one of them on a bus or in a movie theater. Combine these kids on playgrounds with anti-vax kids? What could go wrong? Nothing to worry about. Nothing at all. New Y...
Source: WhiteCoat's Call Room - July 2, 2014 Category: Emergency Medicine Authors: WhiteCoat Tags: Healthcare Update Source Type: blogs

Evaluation of tuberculosis detection indicators in a region with high risk of transmission in Peru.
Authors: Roque-Henríquez J, Catacora-López F, Hilasaca-Yungas G, Romaní-Romaní F Abstract An operational study was conducted to evaluate the tuberculosis detection indicators established in the Technical Standard for Comprehensive Care of Persons Affected by Tuberculosis. Three networks of first level of care facilities with very high risk of tuberculosis transmission from the Tacna region were selected. Using the registry of respiratory symptomatic patients, we analyzed 14,595 respiratory symptomatic subjects (RSS), of which we examined (ExRSS) 14,486 (99.3%). Of the total of ExRSS, 1.5% were BK (+).The averag...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - December 11, 2015 Category: Global & Universal Tags: Rev Peru Med Exp Salud Publica Source Type: research

Association of CD4 T cell count and optimal timing of antiretroviral therapy initiation with immune reconstitution inflammatory syndrome and all-cause mortality for HIV-infected adults with newly diagnosed pulmonary tuberculosis: a systematic review and meta-analysis
CONCLUSIONS: The present study demonstrates that low-baseline CD4 T cell count (< 50 cells/μL) in patients co-infected with TB-HIV increases the incidence of TB-associated IRIS and all-cause mortality. Early ART initiation (≤ 28 days) in patients co-infected with TB-HIV increases the incidence of TB-associated IRIS. However, evidence is insufficient to refute or support a survival benefit conferred by the comparison between early ART initiation (≤ 28 days) and delayed ART initiation.PMID:34239668 | PMC:PMC8255206
Source: International Journal of Clinical and Experimental Pathology - July 9, 2021 Category: Pathology Authors: Lifang Li Jianqiang Li Chunwei Chai Tanzhen Liu Pingping Li Mengrui Qu Hui Zhao Source Type: research