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The Autumn Ghost: How the Battle Against a Polio Epidemic Revolutionized Modern Medical Care : Hannah Wunsch. Greystone Books, Canada, 2023. CAD 39.95, 360 pages. ISBN:  9781771649452
Can J Anaesth. 2023 Aug 8. doi: 10.1007/s12630-023-02553-9. Online ahead of print.NO ABSTRACTPMID:37552400 | DOI:10.1007/s12630-023-02553-9
Source: Canadian Journal of Anaesthesia - August 8, 2023 Category: Anesthesiology Authors: Peter G Brindley Source Type: research

Materials for Controlled Release of Local Anesthetics
ChemMedChem. 2023 Apr 18:e202300009. doi: 10.1002/cmdc.202300009. Online ahead of print.ABSTRACTControlled release systems for prolonged duration local anesthesia have long been an area of research interest, and now are entering clinical practice, in part driven by the opioid epidemic. We discuss the design considerations and material properties of systems for controlled release of local anesthetics, from relatively simple systems to covalent binding of drugs to materials and delivery triggered by external stimuli.PMID:37070644 | DOI:10.1002/cmdc.202300009
Source: ChemMedChem - April 18, 2023 Category: Chemistry Authors: Yang Li Gwen E Owens Daniel S Kohane Source Type: research

A Trauma E-Scooter Epidemic
Anesth Analg. 2023 May 1;136(5):957-959. doi: 10.1213/ANE.0000000000006338. Epub 2023 Apr 14.NO ABSTRACTPMID:37058733 | DOI:10.1213/ANE.0000000000006338
Source: Anesthesia and Analgesia - April 14, 2023 Category: Anesthesiology Authors: Jack Louro Alejandra Silva-De Las Salas Albert J Varon Source Type: research

Health and Well-Being of Intensive Care Unit Physicians: How to Ensure the Longevity of a Critical Specialty
This article reviews the history of burnout in health care workers, presents the signs and symptoms, discusses the specific impact of the COVID-19 pandemic on intensive care unit caregivers, and attempts to identify potential strategies to combat the Great Resignation disproportionately affecting health care workers. The article also focuses on how the specialty can amplify the voices and highlight the leadership potential of underrepresented minorities, physicians with disabilities, and the aging physician population.PMID:36872006 | DOI:10.1016/j.anclin.2022.10.009
Source: Pain Physician - March 5, 2023 Category: Anesthesiology Authors: John C Klick Madiha Syed Ron Leong Haley Miranda Elizabeth K Cotter Source Type: research

Intraoperative pharmacologic opioid minimisation strategies and patient-centred outcomes after surgery: a scoping review protocol
Introduction For close to a century opioid administration has been a standard of care to complement anaesthesia during surgery. Considering the worldwide opioid epidemic, this practice is now being challenged and there is a growing use of systemic pharmacological opioid minimising strategies. Our aim is to conduct a scoping review that will examine clinical trials that have evaluated the impact of intraoperative opioid minimisation strategies on patient-centred outcomes and identify promising strategies. Methods and analysis Our scoping review will follow the framework developed by Arksey and O’Malley. We will searc...
Source: BMJ Open - March 1, 2023 Category: General Medicine Authors: Verret, M., Lam, N. H., Fergusson, D. A., G Nicholls, S., Turgeon, A. F., McIsaac, D. I., Gilron, I., Hamtiaux, M., Srichandramohan, S., Al-Mazidi, A., A Fergusson, N., Hutton, B., Zivkovic, F., Graham, M., Geist, A., Le, M., Berube, M., Poulin, P., Shorr Tags: Open access, Anaesthesia Source Type: research

Burnout Among Chinese Anesthesiologists After the COVID-19 Pandemic Peak: A National Survey
CONCLUSIONS: The impact of the COVID-19 epidemic on the psychological well-being of anesthesiologists still exists more than 1 year after the outbreak. Building better institutional support and cultivating stronger resilience may be helpful future intervention measures.PMID:36729947 | DOI:10.1213/ANE.0000000000006298
Source: Anesthesia and Analgesia - February 2, 2023 Category: Anesthesiology Authors: Lu Che Shuang Ma Yue Lun Zhang Yuguang Huang Source Type: research

Lidocaine inhibits influenza a virus replication by up-regulating IFN α4 via TBK1-IRF7 and JNK-AP1 signaling pathways
In conclusion, our results indicate the potential auxiliary role of lidocaine for anti-influenza A virus therapy and even for anti-SARS-CoV-2 virus therapy, especially in the absence of a specific medicine.PMID:36638664 | DOI:10.1016/j.intimp.2023.109706
Source: International Immunopharmacology - January 13, 2023 Category: Allergy & Immunology Authors: Xueer Liu Fengqing Zheng Lu Tian Tian Li Zelin Zhang Zhihui Ren Xiaoxuan Chen Weiqiang Chen Kangsheng Li Jiangtao Sheng Source Type: research

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