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Infectious Disease: Endemics

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Total 16431 results found since Jan 2013.

The timing setting in kinetic dengue studies: a systematic review
Acta Trop. 2022 Jul 4:106584. doi: 10.1016/j.actatropica.2022.106584. Online ahead of print.ABSTRACTDengue is classified as an endemic infectious disease, which is transmitted by Aedes mosquitos. Kinetic studies, which monitor the viral load of the disease, have been the mainstay for several decades in humanity's quest to control this disease. Our study aims to systematically evaluate the usage of different timing systems in dengue kinetic studies. A search in nine electronic databases and manual search of reference and citation lists were conducted to find relevant studies. A quality assessment using the National Institut...
Source: Acta Tropica - July 7, 2022 Category: Infectious Diseases Authors: Linh Tran Nguyen Minh Tuan Dao Ngoc Hien Tam Abdulmueti Alshareef Essam Emad Ahmed Mohamed Khalifa Truong Hong Hieu Zeeshan Ali Khan Lee Wei Jun Kenji Hirayama Nguyen Tien Huy Source Type: research

The Omicron-transformer: Rise of the subvariants in the age of vaccines
CONCLUSION: Due to current high levels of vaccine- and infection-induced immunity, it is likely that rates of severe illness, hospitalisation, and death due to Omicron will continue to moderate. Nevertheless, the virus is ever-changing, and public health policies, especially those related to vaccinations, will also have to continually evolve and adapt as COVID-19 transitions to endemicity.PMID:36453218 | DOI:10.47102/annals-acadmedsg.2022294
Source: Ann Acad Med Singapo... - December 1, 2022 Category: General Medicine Authors: Travis Ren Teen Chia Barnaby Edward Young Po Ying Chia Source Type: research

Yellow fever vaccine for patients with HIV infection.
CONCLUSIONS: YF vaccination can produce protective levels of neutralising antibodies in HIV patients. Immunogenicity of YF vaccine is slightly less in HIV-infected patients compared to HIV-uninfected patients. No serious adverse events related to YF vaccine were observed in HIV-infected study participants. At time of immunisation, higher CD4 cell counts and lower HIV RNA levels in patients with HIV infection seem to be key determinants for development of protective titres of neutralising antibodies. The quality of the evidence for all outcomes was low to very low. YF vaccine may potentially be used safely in HIV-infected p...
Source: Cochrane Database of Systematic Reviews - January 23, 2014 Category: Journals (General) Authors: Barte H, Horvath TH, Rutherford GW Tags: Cochrane Database Syst Rev Source Type: research

Treatment of Kaposi sarcoma in children with HIV-1 infection.
CONCLUSIONS: Data describing the efficacy of different treatment options for pediatric KS, to include chemotherapy and ART, are sparse. However, the use of ART together with a chemotherapy regimen may be superior to the use of ART alone or of chemotherapy alone. PMID: 24464843 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - February 3, 2014 Category: Journals (General) Authors: Anglemyer A, Agrawal AK, Rutherford GW Tags: Cochrane Database Syst Rev Source Type: research

Primaquine or other 8-aminoquinoline for reducing P. falciparum transmission.
CONCLUSIONS: In individual patients, PQ added to malaria treatments reduces gametocyte prevalence when given in doses greater than 0.4 mg/kg. Whether this translates into preventing people transmitting malaria to mosquitoes has rarely been tested in controlled trials, but there appeared to be a strong reduction in infectiousness in the two small studies that evaluated this. No included trials evaluated whether this policy has an impact on community malaria transmission either in low-endemic settings approaching elimination, or in highly-endemic settings where many people are infected but have no symptoms and are unlikely t...
Source: Cochrane Database of Systematic Reviews - July 3, 2014 Category: Journals (General) Authors: Graves PM, Gelband H, Garner P Tags: Cochrane Database Syst Rev Source Type: research

Face washing promotion for preventing active trachoma.
CONCLUSIONS: There is evidence from one trial that face washing combined with topical tetracycline may be effective in reducing severe active trachoma and in increasing the prevalence of clean faces at one year follow-up. Current evidence is inconclusive as to the effectiveness of face washing alone or in combination with topical tetracycline in reducing active or severe trachoma. PMID: 25697765 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - February 20, 2015 Category: Journals (General) Authors: Ejere HO, Alhassan MB, Rabiu M Tags: Cochrane Database Syst Rev Source Type: research