Filtered By:
Source: The Journal of Heart and Lung Transplantation
This page shows you your search results in order of relevance. This is page number 13.
Order by Relevance | Date
Total 231 results found since Jan 2013.
Left Ventricular Assist Systems and Strokes- Statins to the Rescue?
The development of durable left ventricular assist systems (LVAS) has been critical in providing an option for management of end-stage heart disease and addressing the increasing gap between demand and supply of donor cardiac allografts for management of end-stage heart disease. The technology also provides an alternative to heart transplantation in many patients. Unfortunately, the long-term use of LVAS has been associated with significant morbidities, the most devastating of which may relate to the thrombogenicity of the artificial devices, leading to ischemic stroke or pump thrombosis.
Source: The Journal of Heart and Lung Transplantation - March 16, 2020 Category: Transplant Surgery Authors: Jignesh Patel Tags: Editorial Source Type: research
Intracorporeal VAD Outcomes in the ACTION Quality Improvement Network
The initial project of ACTION (Advanced Cardiac Therapies Improving Outcomes Network) is focused on improving stroke rates in patients implanted with a ventricular assist devices (VAD) in participating centers. The initial interventions targeted improving communication, anticoagulation, and blood pressure management. We sought to describe the characteristics and outcomes of patients implanted with intracorporeal, continuous flow VADs (cfVAD).
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: D.L. Sutcliffe, A.P. Barnes, R.R. Davies, D.S. Machado, M.F. Shezad, B.M. Hawkins, C.S. Almond, J.M. Murray, C.R. Villa Tags: (184) Source Type: research
Pulmonary Vascular Resistances among Heart Transplant Candidates: Are We Looking to the Right Player?
Pulmonary vascular resistances (PVR) are among the key measurements derived from right heart catheterization (RHC) in the prognostic assessment of patients (pts) candidate to Heart Transplantation (HT). PVR however don't account for compliance and pulsatility of pulmonary circulation. Pulmonary arterial compliance (PAC) [stroke volume/pulmonary artery pulse pressure (SV/PAPP)], that is inversely related to PVR, and pulmonary effective arterial elastance (Ea) (sPAP/SV) incorporate compliance and pulsatility of right ventricular afterload.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: M. Masetti, A. Moretta, M. Sabatino, A. Russo, S. Martin Suarez, A. Loforte, N. Gali è, L. Potena Tags: (103) Source Type: research
Hypertension, Arterial Compliance and LVAD Pump Function
Hypertension (HTN) has been implicated as a risk factor for stroke in continuous-flow Left Ventricular Assist Device (LVAD) populations. Active treatment of HTN has been shown to decrease cerebrovascular accident rates in the recent trial. Current guidelines recommend a mean arterial pressure (MAP) of 80mmHg in LVAD patients; however, it is difficult to reliably measure Blood Pressure (BP) in this cohort. Increased BP will further affect pump output since LVAD flows are altered by both preload and afterload.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: A. Adji, S. Shehab, P. Jain, D. Robson, P. Jansz, C. Hayward Tags: (371) Source Type: research
Blood Conservation Strategy at Time of Left Ventricular Assist Device Placement Improves Survival
Bleeding is the most common complication of left ventricular assist device (LVAD) placement. However, excessive transfusion has been linked to heart failure, stroke, and alloimmunization. We compared 90-day outcomes in patients receiving a blood conservation (BCS) versus liberal transfusion strategy during surgery and the subsequent 24 hours.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: K. Stawiarski, O. Agboola, J. Park, A. Mangi, A. Geirsson, F. Lee, D. Jacoby, L. Bellumkonda, T. Ahmad, J. Chou, J.M. Testani, M. Chen, G. McCloskey, P. Bonde Tags: (356) Source Type: research
Pre-Operative Intracardiac Thrombus is Associated with Increased Risk of Stroke and Death in CF-LVAD Patients
Advanced heart failure predisposes patients to intracardiac thrombus (ICT) formation. There is a paucity of evidence examining the impact of pre-existing left atrial (LA) or left ventricular (LV) thrombi on post-operative outcomes in patients undergoing durable LVAD implantation.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: C.A. Bravo Carillo, J.A. Fried, G.M. Mondellini, A. Javaid, H.S. Lumish, J.Z. Willey, V.K. Topkara, L. Braghieri, Y. Kaku, L. Witer, H. Takayama, K. Takeda, Y. Naka, N. Uriel, M. Yuzefpolskaya, P.C. Colombo Tags: (349) Source Type: research
Effect of Donor Death by Drug Intoxication Combined with Chronic Drug Abuse on Lung Transplantation: A Single Center Study
In the field of lung transplantation, there is a high wait list mortality. Broader use of extended criteria donors would provide additional organs for transplantation. An increasing number of organ donors are dying from drug overdose. These donors are often considered “high risk” because of their exposure to infectious diseases such as HIV and Hepatitis B and C. However, these organ donors are often younger and healthier than those that die from stroke or cardiac arrest. Successful use of lung donors who have a history of drug abuse may serve to provide addit ional organs for those patients on the wait list.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: E.C. Klipsch, T. Hathaway, R.S. Mangus Tags: (330) Source Type: research
Inflow Cannula Position as Predictor for Neurological Dysfunction in Patients with HeartMate 3 Left Ventricular Assist Device
This study aimed to investigate pump position, derived from chest X-rays of HM3 patients, in correlation to any neurological dysfunction (ND) and specifically to ischemic stroke (IS) and intracranial hemorrhage (ICH).
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: T. Schl öglhofer, P. Aigner, M. Migas, D. Beitzke, F. Wittmann, J. Riebandt, D. Wiedemann, G. Laufer, F. Moscato, H. Schima, D. Zimpfer Tags: (216) Source Type: research
Left Atrial Volume after Heart Transplantation - A Predictor of Outcomes?
The left atrium (LA) in heart transplant (HT) recipients is a surgically created chamber from variable portions of donor and recipient. In the non-HT patients there is strong evidence that left atrial volume (LAV) is a robust predictor of cardiovascular outcomes such as atrial fibrillation, stroke, heart failure and cardiovascular death. Thus, we thought to 1) characterize LA size in HT recipients and 2) investigate the implications of “new” LA volume on HT outcomes.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: Y. Peled, J. Lavee, E. Ram, Y. Kassif, L. Sternik, E. Schwammenthal, R. Klempfner, B. Tzur Tags: (614) Source Type: research
Ischemic Stroke and Intracranial Hemorrhages during Percutaneous Left Ventricular Assist Device Cardiac Support
Mechanical circulatory support systems for cardiogenic shock and heart failure are associated with ischemic strokes and intracranial hemorrhages. Impella is a percutaneously placed, ventricular assist device for short-term cardiac support. We aimed to study the prevalence of acute neurologic complications during short-term support with Impella.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: C. Hassett, S. Cho, S. Hasan, R.C. Starling, E. Soltesz, K. Uchino, I. Migdady Tags: (994) Source Type: research
Outpatient Cardiac Palliative Care Reduces Healthcare Utilization
The American Heart Association and American Stroke Association have put forth statement recommending early and continuous access to palliative care for patients with heart disease. There is a national shortage of palliative care providers, and often outpatient palliative care clinics are not profitable to institutions with billing alone. However, early integration of palliative care has been proven to improve the quality of life of patients with advanced heart failure. Other studies have suggested that general palliative care has cost savings to hospital systems.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: T.A. Barrett Tags: (907) Source Type: research
Feasibility and Accuracy of Blood Pressure Measurement by Patients with Left Ventricular Assist Devices (LVAD)
Blood pressure (BP) control reduces stroke in LVAD patients. Home monitoring is key for optimal control. Measurement by Doppler is the most reliable non-invasive method. No study assessed the feasibility of Doppler BP obtained by LVAD patients and caregivers.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: V. Ton, L. Dees, J. Casida, S. Ledroux, E.N. Sorensen, R. Madathil, D. Kaczorowski Tags: (849) Source Type: research
Two-Year Outcomes in HeartMate 3 versus HeartWare HVAD Patients Implanted as Destination Therapy
The ENDURANCE trial demonstrated noninferiority of the intrapericardial centrifugal-flow HeartWare HVAD compared to the axial-flow HeartMate II left ventricular assist device (LVAD) regarding survival in patients with advanced heart failure ineligible for heart transplantation, but stroke was more common. Most recently, the MOMENTUM 3 trial demonstrated superiority of the intrathoracic, fully magnetically levitated centrifugal-flow HeartMate 3 (HM3) LVAD compared to the HeartMate II. A clinical trial evaluating the HM3 and HVAD has not been performed, therefore the purpose of this study was to compare outcomes between these two devices.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: L. Coyle, C. Gallagher, L. Kukla, R. Paliga, R. Siemeck, G. Yost, M. Dia, A. Tatooles Tags: (1039) Source Type: research
Physiologically Significant Pulsatility Key to Reducing Adverse Events in CF LVADS
Hypertension is common in continuous flow LVAD (CFLVAD) patients and is linked to major adverse events like stroke and aortic incompetence.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: K. Balakrishnan, R. Krishnakumar Tags: (1037) Source Type: research
Pulmonary Artery Pulsatility Index (PAPi) is a Predictor of Right Ventricular Assist Device (RVAD) Use Following HeartMate 3 LVAD Implantation
Pulmonary artery pulsatility index (PAPi) recently emerged as a predictor of right ventricular failure after Heartmate II LVAD Implantation. Clinical utility of this marker in Heartmate 3 patients is unknown. We hypothesized that PAPi is a stronger predictor of RV failure compared to central venous pressure to pulmonary artery capillary wedge pressure ratio (CVP/PCWP) or RV stroke work index (RVSWI) in Heartmate 3 population.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: D. Marshall, A. Malick, L. Truby, C. Butler, J. Griffin, K. Clerkin, J. Fried, J. Raikhelkar, M. Yuzefpolskaya, P. Colombo, G. Sayer, H. Takayama, K. Takeda, Y. Naka, M. Farr, N. Uriel, V.K. Topkara Tags: (1031) Source Type: research
