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Total 74 results found since Jan 2013.
The interplay of physical and cognitive function in rehabilitation of interstitial lung disease patients: a narrative review
CONCLUSIONS: Numerous underlying etiologies of ILD contribute to frailty, skeletal muscle and cognitive function, but their respective neurobiologic mechanisms require further investigation. Exercise training increases physical measures, but complementary approaches may improve their applicability to improve daily activities.PMID:37691666 | PMC:PMC10482628 | DOI:10.21037/jtd-23-209
Source: Journal of Thoracic Disease - September 11, 2023 Category: Respiratory Medicine Authors: Masatoshi Hanada Takako Tanaka Ryo Kozu Yuji Ishimatsu Noriho Sakamoto Ani Orchanian-Cheff Dmitry Rozenberg W Darlene Reid Source Type: research
Clinical phenotypes and quality of life to define post-COVID-19 syndrome: a cluster analysis of the multinational, prospective ORCHESTRA cohort
EClinicalMedicine. 2023 Jul 21;62:102107. doi: 10.1016/j.eclinm.2023.102107. eCollection 2023 Aug.ABSTRACTBACKGROUND: Lack of specific definitions of clinical characteristics, disease severity, and risk and preventive factors of post-COVID-19 syndrome (PCS) severely impacts research and discovery of new preventive and therapeutics drugs.METHODS: This prospective multicenter cohort study was conducted from February 2020 to June 2022 in 5 countries, enrolling SARS-CoV-2 out- and in-patients followed at 3-, 6-, and 12-month from diagnosis, with assessment of clinical and biochemical features, antibody (Ab) response, Variant o...
Source: Cell Research - September 1, 2023 Category: Cytology Authors: Elisa Gentilotti Anna G órska Adriana Tami Roy Gusinow Massimo Mirandola Jes ús Rodríguez Baño Zaira R Palacios Baena Elisa Rossi Jan Hasenauer Iris Lopes-Rafegas Elda Righi Natascia Caroccia Salvatore Cataudella Zeno Pasquini Thomas Osmo Lidia Del Pi Source Type: research
Baseline Body Surface Area and Itch Severity Define Response to Baricitinib in Patients with Moderate-to-Severe Atopic Dermatitis at Week 16
CONCLUSION: Using a machine learning approach, patients with moderate-to-severe AD and a BSA affecting 10-40% and Itch NRS ≥ 7 were characterized as likely to benefit most from BARI 4-mg TCS combination therapy. This was confirmed by subgroup analyses, which showed that these patients are most likely to show favorable response rates in improving AD signs and symptoms, specifically itch, after 16 weeks of treatment.PMID:37332021 | DOI:10.1007/s12325-023-02528-8
Source: Adv Data - June 18, 2023 Category: Epidemiology Authors: Jacob P Thyssen Marjolein de Bruin-Weller Antonio Costanzo Susanne Grond Christopher Schuster Chunyuan Liu Maria Jose Rueda Yun-Fei Chen Andreas Pinter Thomas Bieber Source Type: research
Investigational medications in 9,638 hospitalized patients with severe COVID-19: lessons from the "fail-and-learn" strategy during the first two waves of the pandemic in 2020
CONCLUSION: This retrospective multicenter observational cohort study on 9,638 hospitalized patients with severe COVID-19 during revealed that the necessity for invasive ventilation had the highest odds of mortality, beyond the variable effects observed by administration of the prevalent EUA-approved investigational drugs during the first two surges of the early 2020 pandemic in the United States.PMID:37041643 | DOI:10.1186/s13037-023-00358-9
Source: Patient Safety in Surgery - April 11, 2023 Category: Surgery Authors: Adam C Delgado Brendon Cornett Ye Ji Choi Christina Colosimo Vincent P Stahel Oliwier Dziadkowiec Philip F Stahel Source Type: research
