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Neuropsychological changes following deep brain stimulation surgery for Parkinson's disease: comparisons of treatment at pallidal and subthalamic targets versus best medical therapy
Conclusions In those with PD, the likelihood of significant decline in neuropsychological functioning increases with DBS, affecting a small minority of patients who also appear to respond less optimally to DBS by other indicators of QOL. Trial registration number NCT00056563 and NCT01076452.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 14, 2015 Category: Neurosurgery Authors: Rothlind, J. C., York, M. K., Carlson, K., Luo, P., Marks, W. J., Weaver, F. M., Stern, M., Follett, K., Reda, D., Ippolito, Stoner, Barnett, Bukowski, DeNicolo, Hur, Jimenez, Motyka, Simon, Thakkar, Woolson, Fye, Gagne, Harris, Heemskerk, Moy, Sheehy, O' Tags: Drugs: CNS (not psychiatric), Parkinson's disease, Stroke, Memory disorders (psychiatry) Multiple sclerosis Source Type: research

Linking Essential Tremor to the Cerebellum: Clinical Evidence
Abstract Essential tremor (ET) might be a family of diseases unified by the presence of kinetic tremor, but also showing etiological, pathological, and clinical heterogeneity. In this review, we will describe the most significant clinical evidence, which suggests that ET is linked to the cerebellum. Data for this review were identified by searching PUBMED (January 1966 to May 2015) crossing the terms “essential tremor” (ET) and “cerebellum,” which yielded 201 entries, 11 of which included the term “cerebellum” in the article title. This was supplemented by articles in the author’s files that pertaine...
Source: The Cerebellum - October 31, 2015 Category: Neurology Source Type: research

Linking Essential Tremor to the Cerebellum: Clinical Evidence.
Abstract Essential tremor (ET) might be a family of diseases unified by the presence of kinetic tremor, but also showing etiological, pathological, and clinical heterogeneity. In this review, we will describe the most significant clinical evidence, which suggests that ET is linked to the cerebellum. Data for this review were identified by searching PUBMED (January 1966 to May 2015) crossing the terms "essential tremor" (ET) and "cerebellum," which yielded 201 entries, 11 of which included the term "cerebellum" in the article title. This was supplemented by articles in the author's files that pertained to this topi...
Source: Cerebellum - October 31, 2015 Category: Neuroscience Authors: Benito-León J, Labiano-Fontcuberta A Tags: Cerebellum Source Type: research

Sensory Re-weighting for Postural Control in Parkinson ’s Disease
In this study, we focused primarily on the change of sensory weighting parameters when sensory conditions change. We also tested the additional hypothesis that levodopa medication would improve sensory weighting for postural control. Materials and Methods Subjects The Institutional Review Board at Oregon Health and Science University (OHSU) approved the protocol for this experiment, and all subjects gave informed consent prior to participating. Eight subjects with PD (three female) and eight healthy, age-matched controls (two female) were recruited from the Balance Disorders Laboratory database and the Parkinson’...
Source: Frontiers in Human Neuroscience - April 16, 2019 Category: Neuroscience Source Type: research

What Are Some Risk Factors for Cerebral Palsy?
Discussion The term, cerebral palsy, or CP has gone through many iterations with the first description in 1861 by W.J. Little who described it as “The condition of spastic rigidity of the limbs of newborn children.” The most recent definition is from Rosenbaun et al. in 2007 which states it is “a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cog...
Source: PediatricEducation.org - March 9, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news