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Total 433 results found since Jan 2013.

Clinical phenotypes and quality of life to define post-COVID-19 syndrome: a cluster analysis of the multinational, prospective ORCHESTRA cohort
EClinicalMedicine. 2023 Jul 21;62:102107. doi: 10.1016/j.eclinm.2023.102107. eCollection 2023 Aug.ABSTRACTBACKGROUND: Lack of specific definitions of clinical characteristics, disease severity, and risk and preventive factors of post-COVID-19 syndrome (PCS) severely impacts research and discovery of new preventive and therapeutics drugs.METHODS: This prospective multicenter cohort study was conducted from February 2020 to June 2022 in 5 countries, enrolling SARS-CoV-2 out- and in-patients followed at 3-, 6-, and 12-month from diagnosis, with assessment of clinical and biochemical features, antibody (Ab) response, Variant o...
Source: Cell Research - September 1, 2023 Category: Cytology Authors: Elisa Gentilotti Anna G órska Adriana Tami Roy Gusinow Massimo Mirandola Jes ús Rodríguez Baño Zaira R Palacios Baena Elisa Rossi Jan Hasenauer Iris Lopes-Rafegas Elda Righi Natascia Caroccia Salvatore Cataudella Zeno Pasquini Thomas Osmo Lidia Del Pi Source Type: research

"Hi, How Can I Help You?" Embracing Artificial Intelligence in Kidney Research
Am J Physiol Renal Physiol. 2023 Aug 17. doi: 10.1152/ajprenal.00177.2023. Online ahead of print.ABSTRACTIn recent years, biology and precision medicine have benefited from the major advancements in generating large-scale molecular and biomedical datasets and in analyzing those data using advanced machine learning algorithms. Machine learning applications in kidney physiology and pathophysiology include segmenting kidney structures from imaging data and predicting conditions like acute kidney injury or chronic kidney disease using electronic health records. Despite the potential of machine learning to revolutionize nephrol...
Source: Am J Physiol Renal P... - August 17, 2023 Category: Urology & Nephrology Authors: Anita T Layton Source Type: research

Greater executive dysfunction in patients post-COVID-19 compared to those not infected
Brain Behav Immun. 2023 Aug 14:S0889-1591(23)00237-4. doi: 10.1016/j.bbi.2023.08.014. Online ahead of print.ABSTRACTBACKGROUND: A number of patients post-coronavirus disease-19 (COVID-19) report cognitive impairment (CI), even months after acute infection. We aimed to assess if COVID-19 is associated with increased incidence of CI in comparison to controls.METHODS: We analyzed data from the Mount Sinai Health System Post-COVID-19 Registry in New York City, a prospective cohort of patients post-COVID-19 ≥18 years of age and non-infected controls. CI was defined by scores ≥1.0 standard deviation below population norms, a...
Source: Brain, Behavior, and Immunity - August 16, 2023 Category: Neurology Authors: Jacqueline H Becker Jenny J Lin Akosua Twumasi Ruchir Goswami Fernando Carnavali Kimberly Stone Monica Rivera-Mindt Minal S Kale Georges Naasan Joanne R Festa Juan P Wisnivesky Source Type: research