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Total 2417 results found since Jan 2013.

How John Fetterman Came Out of the Darkness
When he looks back on the past year—a year in which he nearly died, became a U.S. Senator, and nearly died again—it is the debate that John Fetterman identifies as the ­breaking point. “The debate lit the mitch,” he says, then shakes his head in frustration and tries again. The right word is there in his brain, but he struggles to get it out. “Excuse me, that should be lit the mitch—” He stops and tries again. “Lit the match,” he says finally. Oct. 25, 2022: the date is lodged in his mind. “I knew I had to do it,” he tells me. “I knew that the vote...
Source: TIME: Health - July 20, 2023 Category: Consumer Health News Authors: Molly Ball Tags: Uncategorized Congress Cover Story Exclusive feature uspoliticspolicy Source Type: news

PerIoperative iNflammatory reSponse assessment In hiGH-risk patienTs undergoing non-cardiac surgery (INSIGHT): study protocol of a prospective non-interventional observational study
This study was approved by the ethics committees at the Medical University of Vienna (2458/2020) and at the Medical University of Graz (33-274 ex 20/21). Trial registration number NCT04753307.
Source: BMJ Open - July 19, 2023 Category: General Medicine Authors: Pichler, A., Kurz, A., Eichlseder, M., Graf, A., Eichinger, M., Taschner, A., Kabon, B., Fleischmann, E., Reiterer, C., for the INSIGHT study group, Pichler, Reiterer, Eichlseder, Graf, Eichinger, Kabon, Hantakova, Schallmeiner, Kuhrn, Kurz, Taschner, Fre Tags: Open access, Anaesthesia Source Type: research

Genes, Vol. 14, Pages 1448: Isoflurane Anesthesia & rsquo;s Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model
Conclusions: We were able to determine the effects of the duration of anesthesia using isoflurane on the transcriptomes in the brains of rats at 24 h after tMCAO. Thus, specific genome responses may be useful in developing potential approaches to reduce damaged areas after cerebral ischemia and neuroprotection.
Source: Genes - July 14, 2023 Category: Genetics & Stem Cells Authors: Yana Y. Shpetko Ivan B. Filippenkov Alina E. Denisova Vasily V. Stavchansky Leonid V. Gubsky Svetlana A. Limborska Lyudmila V. Dergunova Tags: Article Source Type: research

The association between intraoperative fluid management and perioperative allogenic blood transfusion during adolescent idiopathic scoliosis surgery
CONCLUSION: These results indicate a statistical association between the increase in crystalloid intake and the risk of allogenic blood transfusion during surgical correction of adolescent idiopathic scoliosis. Controlled studies are needed to address the causative relation between intraoperative fluid intake and the risk of allogenic transfusion.PMID:37386846 | DOI:10.1111/pan.14722
Source: Paediatric Anaesthesia - June 30, 2023 Category: Anesthesiology Authors: Pierre Pardessus Maud Loiselle Vilnis Silins Anne-Laure Horlin Kelly Brouns Lucile Marsac Charlotte Fait Brice Ilharreborde Florence Julien-Marsollier Souhayl Dahmani Source Type: research

Association of cervical atherosclerosis on Doppler ultrasonography and postoperative delirium in patients undergoing spinal surgery: a single-center, retrospective, observational study
CONCLUSIONS: There was a significant association between POD and the prevalence of cervical atherosclerosis using the univariate logistic regression analysis. Furthermore, multivariate logistic regression analyses showed that older age and antiplatelet agent use were independently associated with POD.PMID:37326838 | DOI:10.1007/s00586-023-07823-0
Source: Atherosclerosis - June 16, 2023 Category: Cardiology Authors: Gentaro Kumagai Kanichiro Wada Toru Asari Yohshiro Nitobe Hirotaka Kinoshita Tetsuya Kushikata Kazuyoshi Hirota Yasuyuki Ishibashi Source Type: research

The Effect of Intraoperative Hypotension on Postoperative Renal Function
AbstractPurpose of ReviewThis review summarizes the most recent literature on the association between intraoperative hypotension (IOH) and the occurrence of postoperative acute kidney injury (AKI). It provides recommendations for the management of intraoperative blood pressure to reduce the incidence of postoperative AKI. Fluid management strategies, administration of vasopressor medications, and other methods for reducing the incidence of AKI are also briefly discussed.Recent FindingsRecent retrospective studies have demonstrated a solid association of IOH with postoperative AKI. IOH is associated not only with AKI but al...
Source: Current Anesthesiology Reports - June 14, 2023 Category: Anesthesiology Source Type: research

General anesthesia or conscious sedation for thrombectomy in stroke patients: an updated systematic review and meta-analysis
CONCLUSIONS: In this updated systematic review and meta-analysis, the choice of anesthetic strategy for endovascular treatment of stroke patients did not significantly impact functional outcome as measured with the mRS at three months. Patients managed with general anesthesia may have more frequent successful reperfusion.TRIAL REGISTRATION: PROSPERO (CRD42022319368); registered 19 April 2022.PMID:37268801 | DOI:10.1007/s12630-023-02481-8
Source: Canadian Journal of Anaesthesia - June 2, 2023 Category: Anesthesiology Authors: Federico Geraldini Paolo Diana Davide Fregolent Alessandro De Cassai Annalisa Boscolo Tommaso Pettenuzzo Nicol ò Sella Irene Lupelli Paolo Navalesi Marina Munari Source Type: research