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Hematocrit and Stroke: A Forgotten and Neglected Link?
Semin Thromb Hemost DOI: 10.1055/s-0037-1602663Stroke is considered among the most common causes of mortality and disability, leading to dramatic socioeconomic consequences. From a pathophysiologic perspective, enhanced blood viscosity due to increased hematocrit might be associated with stroke through impaired cerebral blood perfusion. This association has remained rather neglected during previous decades, but newly emerged as an epicenter of scientific interest due to the unexpected elevation of stroke rates with sodium-glucose cotransporter-2 inhibitors, a new class of hypoglycemic drugs with otherwise dramatic cardiova...
Source: Seminars in Thrombosis and Hemostasis - June 13, 2017 Category: Hematology Authors: Stavropoulos, Konstantinos Imprialos, Konstantinos P. Bouloukou, Sofia Boutari, Chrysoula Doumas, Michael Tags: Review Article Source Type: research

Dynamic perfusion analysis in acute ischemic stroke: A comparative study of two different softwares
CONCLUSIONS: Although the absolute values have a certain degree of variation, both software programs have good agreement with each other.PMID:34420946 | DOI:10.3233/CH-219106
Source: Clinical Hemorheology and Microcirculation - August 23, 2021 Category: Hematology Authors: Cornelius Krusche Carolina Rio Bartulos Mazen Abu-Mugheisib Michael Haimerl Philipp Wiggermann Source Type: research

Contrast-enhanced ultrasound perfusion patterns and serum lipid signatures of vulnerable carotid artery plaque in predicting stroke: A cohort study of carotid stenosis in Chinese patients.
CONCLUSION: A high level of CEUS perfusion and increased serum FFA levels are indicative of vulnerable carotid plaques, which may be useful for the prediction of stroke in patients with carotid artery disease. PMID: 32039838 [PubMed - as supplied by publisher]
Source: Clinical Hemorheology and Microcirculation - February 6, 2020 Category: Hematology Authors: Huang Y, Liu Q, Xu J, Zhu W, Jiang J, Tang L, Chen M Tags: Clin Hemorheol Microcirc Source Type: research

Utility of intestinal intravital microscopy for the study of CNS injury-induced immunodepression syndrome (CIDS)
CONCLUSIONS: Our results suggest that PTS with subsequent LPS challenge poses as a viable model to further study CIDS using intravital microscopy of the intestinal microcirculation.PMID:34487026 | DOI:10.3233/CH-219109
Source: Clinical Hemorheology and Microcirculation - September 6, 2021 Category: Hematology Authors: Bashir Bietar Juan Zhou Christian Lehmann Source Type: research

Efficacy and Safety of Direct Oral Factor Xa Inhibitors in 795 Morbidly Obese Patients
Conclusions: Our study is the largest study examining morbidly obese patients on DOACS and provides further evidence of comparable efficacy and safety of the direct oral anti-Xa inhibitors, compared to warfarin, in morbidly obese patients with AF and VTE.DisclosuresKushnir: Janssen: Research Funding. Billett: Bayer: Consultancy; Janssen: Research Funding.
Source: Blood - November 21, 2018 Category: Hematology Authors: Kushnir, M., Choi, Y., Eisenberg, R., Rao, D., Tolu, S., Gao, J., Mowrey, W., Billett, H. H. Tags: 332. Antithrombotic Therapy: Management of Challenging Patients and Scenarios Source Type: research

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