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Specialty: Neurology
Education: Study
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Total 93 results found since Jan 2013.

Enhanced Detection of Edema in Malignant Anterior Circulation Stroke (EDEMA) Score Brief Report
Conclusions—The EDEMA score identifies patients at high risk for potentially lethal malignant edema. Although it requires external validation, this scale could help expedite triage decisions in this patient population.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Charlene Jennifer Ong, Jeffrey Gluckstein, Osvaldo Laurido-Soto, Yan Yan, Rajat Dhar, Jin-Moo Lee Tags: Clinical Studies, Cerebrovascular Disease/Stroke, Ischemic Stroke, Thrombosis Brief Reports Source Type: research

Safety and Effect of Metoclopramide to Prevent Pneumonia in Patients With Stroke Fed via Nasogastric Tubes Trial Clinical Sciences
Conclusions— This study suggests that metoclopramide may reduce the rate of pneumonia and may improve other clinical outcomes in patients with subacute stroke fed via nasogastric tube. These findings need to be confirmed in larger randomized and blinded trials. Clinical Trial Registration— URL: https://www.clinicaltrialsregister.eu. EudraCT no: 2006-002570-22, URL: http://www.controlled-trials.com/ISRCTN18034911/18034911.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Warusevitane, A., Karunatilake, D., Sim, J., Lally, F., Roffe, C. Tags: Nutrition, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Time From Imaging to Endovascular Reperfusion Predicts Outcome in Acute Stroke Clinical Sciences
Conclusions—Compared with target mismatch patients, those with the malignant profile experience faster infarct growth and a steeper decline in the odds of functional independence, with longer delays between baseline imaging and reperfusion. However, this does not exclude the possibility of treatment benefit in patients with a malignant profile.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Jenny P. Tsai, Michael Mlynash, Soren Christensen, Stephanie Kemp, Sun Kim, Nishant K. Mishra, Christian Federau, Raul G. Nogueira, Tudor G. Jovin, Thomas G. Devlin, Naveed Akhtar, Dileep R. Yavagal, Roland Bammer, Matus Straka, Gregory Zaharchuk, Michael Tags: Revascularization, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Prospective Study Of Acute Ischemic Stroke Sub-Types In A Teritiary Care Hospital In South India (P4.283)
Conclusion: The study contributes to understanding of demographic characteristics, risk factors and stroke-subtype in acute ischemic stroke. Like other studies LVA is the commonest subtype and intra-cranial vessels are commonly involved as in other Asian studies.Disclosure: Dr. Garuda has nothing to disclose. Dr. Uppaturi has nothing to disclose. Dr. T has nothing to disclose. Dr. S has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Garuda, B., Uppaturi, A. K., Sateesh Kumar, T., Gopi, S. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Ischemic Stroke Care Source Type: research

Remote poststroke headache in children: Characteristics and association with stroke recurrence
Conclusions Remote poststroke headache is a common morbidity among pediatric stroke survivors, particularly in older children. Headaches may increase health care utilization, including neuroimaging and hospital admissions. We identified a possible association between poststroke headache and stroke recurrence.
Source: Neurology Clinical Practice - June 9, 2019 Category: Neurology Authors: Chelse, A. B., Kurz, J. E., Gorman, K. M., Epstein, L. G., Balmert, L. C., Ciolino, J. D., Wainwright, M. S. Tags: Childhood stroke, Secondary headache disorders, Pediatric headache, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke, Risk factors in epidemiology Research Source Type: research

Prehospital thrombolysis in acute stroke: Results of the PHANTOM-S pilot study
Conclusions: The data suggest that prehospital stroke care in STEMO is feasible. No safety concerns have been raised so far. This new approach using prehospital tPA may be effective in reducing call-to-needle times, but this is currently being scrutinized in a prospective controlled study.
Source: Neurology - January 7, 2013 Category: Neurology Authors: Weber, J. E., Ebinger, M., Rozanski, M., Waldschmidt, C., Wendt, M., Winter, B., Kellner, P., Baumann, A., Fiebach, J. B., Villringer, K., Kaczmarek, S., Endres, M., Audebert, H. J., for the STEMO-Consortium Tags: CT, All Cerebrovascular disease/Stroke, Critical care, Patient safety ARTICLE Source Type: research

High values of baseline and 24-hour Mean Arterial Pressure are associated with lower chance of early neurological improvement in acute stroke patients treated with thrombolysis (P4.286)
Conclusions:High baseline and 24-hr MAP values are associated with lower chance of achieving ENI after IV thrombolysis. Further studies are needed to better understand whether acute BP dysregulation can influence different clinical courses in the early phase of IV thrombolysis.Disclosure: Dr. Lorenzano has nothing to disclose. Dr. Caselli has nothing to disclose. Dr. Zingaro has nothing to disclose. Dr. Orlando has nothing to disclose. Dr. Toni has received research support from Bayer, Medtronic, and Boehriger Ingelheim.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Lorenzano, S., Caselli, M. C., Zingaro, A., Orlando, F., Toni, D. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

A Blood-based Biomarker Panel to Detect Acute Stroke
Background: The aim of this study was to develop an adjunctive, peripheral biomarker test to differentiate ischemic strokes, intracranial hemorrhages (ICHs), and stroke mimics in the acute setting.Methods: Serum samples were collected from 167 patients who presented with an acute neurologic deficit within 24 hours of symptom onset. Patients were adjudicated to ischemic stroke, ICH, and mimic pathology groups based on clinical and radiographic findings. Samples were tested for levels of 262 potential markers. A multivariate Cox proportional hazards regression model of 5 biomarkers was built by stepwise selection and valida...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Richa Sharma, Stephanie Macy, Kara Richardson, Yuliya Lokhnygina, Daniel T. Laskowitz Tags: Original Articles Source Type: research

Timing of symptomatic intracerebral hemorrhage after rt-PA treatment in ischemic stroke
Conclusions Our findings suggest that rt-PA patients have the highest risk of post rt-PA sICH within the first 24 hours after treatment. This supports monitoring of rt-PA-treated patients in specialized settings such as neuro-intensive care units or stroke units. Our findings suggest that the probability of sICH is low 36 hours post rt-PA. Future larger studies are warranted to identify the patterns of bleeding after rt-PA administration.
Source: Neurology Clinical Practice - August 11, 2019 Category: Neurology Authors: Chen, P. M., Lehmann, B., Meyer, B. C., Rapp, K., Hemmen, T., Modir, R., Agrawal, K., Hailey, L., Mortin, M., Meyer, D. M. Tags: All Cerebrovascular disease/Stroke, Intracerebral hemorrhage Research Source Type: research

Pathogenesis and Risk Factors for Cerebral Infarct After Surgical Aortic Valve Replacement Brief Reports
Conclusions— The principal mechanism of acute cerebral infarction after aortic valve replacement is embolism. There are distinct factors associated with watershed and embolic infarct, some of which may be modifiable.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Massaro, A., Messe, S. R., Acker, M. A., Kasner, S. E., Torres, J., Fanning, M., Giovannetti, T., Ratcliffe, S. J., Bilello, M., Szeto, W. Y., Bavaria, J. E., Mohler, E. R., Floyd, T. F., for the Determining Neurologic Outcomes From Valve Operations (DeNO Tags: Valvular Heart Disease, Magnetic Resonance Imaging (MRI), Cardiovascular Surgery, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Rapidly improving neurological deficit of stroke; case series in Academic institute, KAUH, Jeddah (P4.283)
Conclusions:Rapidly improving patient represent a challenge to whether tPA should be given. However, the good outcome with thrombolytic therapy observed in our study, will hopfuly support the decision to treat.Study Supported by: nonDisclosure: Dr. khoja has nothing to disclose. Dr. Alshaer has nothing to disclose. Dr. al-Turkistani has nothing to disclose. Dr. Al-Mekhalfi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: khoja, a., Al-Shaer, D., al-Turkistani, a., Al-Mekhalfi, M. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Intravenous Versus Intra-arterial Thrombolysis for Anterior Circulation Stroke Secondary to Large Vessel Occlusion
This study compared the radiographic and clinical outcomes of 51 patients who underwent intravenous thrombolysis (IVT) with recombinant tissue plasminogen activator (rtPA) with 46 patients who underwent intra-arterial thrombolysis (IAT) with Penumbra System clot aspiration device (Penumbra, Alameda, CA) with or without the Solitaire stentriever device (ev3, Irvine, CA).
Source: Journal of Stroke and Cerebrovascular Diseases - January 16, 2015 Category: Neurology Authors: Dale Ding Tags: Letter to the Editor Source Type: research

Symptomatic Carotid Occlusion Is Frequently Associated With Microembolization Clinical Sciences
Conclusions—Cerebral embolization plays an important role in the pathophysiology of ischemia in both carotid occlusion and stenosis, even among patients with watershed infarcts. The role of aggressive antithrombotic and antiplatelet therapy for symptomatic carotid occlusions may warrant further investigation given our findings.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Ava L. Liberman, Ali Zandieh, Caitlin Loomis, Jonathan M. Raser–Schramm, Christina A. Wilson, Jose Torres, Koto Ishida, Swaroop Pawar, Rebecca Davis, Michael T. Mullen, Steven R. Messe, Scott E. Kasner, Brett L. Cucchiara Tags: Clinical Studies, Pathophysiology, Cerebrovascular Disease/Stroke, Stenosis Original Contributions Source Type: research

Direct Aspiration versus Stent Retriever Thrombectomy for Acute Stroke: A Systematic Review and Meta-Analysis in 9127 Patients
Background: The two most common approaches to thrombectomy of emergent large vessel occlusion (direct aspiration and primary stent retriever thrombectomy) have been extensively studied; however, the detailed benefit and risk comparison is largely unknown. Objective: To conduct a systematic review and meta-analysis to compare radiographic and clinical outcomes between the use of primary stent retrievers and direct aspiration in management of acute ischemic stroke. Methods: PubMed database was searched for studies between September 1, 2012 and December 31, 2017 with acute ischemic stroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - February 13, 2019 Category: Neurology Authors: Christopher T. Primiani, Angel Chinea Vicente, Michael T. Brannick, Aquilla S. Turk, J Mocco, Elad I. Levy, Adnan H. Siddiqui, Maxim Mokin Source Type: research

Ischemic Stroke and Asymptomatic Pulmonary Opacities
Pulmonary opacities are described in many chest radiograph reports in stroke patients and are often asymptomatic. The aim of this study is to investigate the clinical features associated with asymptomatic pulmonary opacities (APO) and evaluate APO prognostic value in ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - December 3, 2021 Category: Neurology Authors: Carmelo Tiberio Curr ò, Masina Cotroneo, Antonio Ciacciarelli, Cristina Dell'Aera, Francesco Grillo, Paolino La Spina, Maria Carolina Fazio, Angelina Laganà, Jolanda De Caro, Giuseppe Trimarchi, Antonio Toscano, Rosa Fortunata Musolino, Carmela Casella Source Type: research