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Off-pump coronary artery bypass grafting in left main stem stenosis: outcomes, concerns and controversies.
Authors: Athanasopoulos LV, Athanasiou T Abstract Left main stem (LMS) disease is known to be a poor prognostic factor in terms of morbidity or mortality. Traditionally, it has been treated with constitution of bypass to provide required haemodynamic stability. We searched the literature for evidence on off-pump (OFP) surgery for treating this high-risk group of patients focusing in our review on postoperative outcomes, concerns and controversies. The majority of the studies identified showed favourable or equal outcomes of OFP when compared to conventional approach. All of the studies, apart from two, which showed...
Source: Journal of Thoracic Disease - December 14, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Outcome of extracorporeal membrane oxygenation support for complex high-risk elective percutaneous coronary interventions: A single-center experience
Conclusions Elective high-risk PCI supported by ECMO is a viable alternative for patients who are at very high risk for CABG.
Source: Heart and Lung: The Journal of Acute and Critical Care - June 15, 2015 Category: Respiratory Medicine Source Type: research

Current outcomes of off-pump versus on-pump coronary artery bypass grafting: evidence from randomized controlled trials.
Authors: Fudulu D, Benedetto U, Pecchinenda GG, Chivasso P, Bruno VD, Rapetto F, Bryan A, Angelini GD Abstract Coronary artery bypass grafting remains the standard treatment for patients with extensive coronary artery disease. Coronary surgery without use of cardiopulmonary bypass avoids the deleterious systemic inflammatory effects of the extracorporeal circuit. However there is an ongoing debate surrounding the clinical outcomes after on-pump versus off-pump coronary artery bypass (ONCAB versus OPCAB) surgery. The current review is based on evidence from randomized controlled trials (RCTs) and meta-analyses of ra...
Source: Journal of Thoracic Disease - December 14, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Impact of sleep disordered breathing on short-term post-operative outcome after elective coronary artery bypass graft surgery: a prospective observational study
Sleep disordered breathing (SDB) is common in patients with coronary disease, but its impact on post-operative recovery after coronary artery bypass graft surgery (CABG) is unclear. We therefore determined the effects of SDB on post-operative outcome after elective CABG. In this prospective two-centre study, 219 patients due to receive elective CABG underwent cardiorespiratory polygraphy for SDB prior to surgery and were monitored for post-operative complications. The primary end-point was a composite of 30-day mortality or major post-operative complications (cardiac, respiratory, surgical, infectious, acute renal failure ...
Source: European Respiratory Journal - April 5, 2017 Category: Respiratory Medicine Authors: Rupprecht, S., Schultze, T., Nachtmann, A., Rastan, A. J., Doenst, T., Schwab, M., Witte, O. W., Rohe, S., Zwacka, I., Hoyer, H. Tags: Original Articles: Sleep Source Type: research

On-pump beating heart versus conventional coronary artery bypass grafting: comparative study on early and long-term clinical outcomes.
Conclusions: The OPB strategy may be as safe and effective as the conventional strategy during CABG among patients with similar risk profiles. A prospective randomized trial is warranted to better ascertain the beneficial impact of OPB-CABG as both a viable and a durable alternative strategy to C-CABG. PMID: 29997927 [PubMed]
Source: Journal of Thoracic Disease - July 14, 2018 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Triglyceride glucose index for predicting cardiovascular outcomes in patients with coronary artery disease.
Conclusions: The present study, firstly, showed that TyG index was positively associated with future CVEs, suggesting that TyG may be a useful marker for predicting clinical outcomes in patients with CAD. PMID: 30622785 [PubMed]
Source: Journal of Thoracic Disease - January 11, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Secondary prevention advices after cardiovascular index event: From drug prescription to risk factors control in real world practice.
Authors: Faggiano P, Fattirolli F, Frisinghelli A, Piccioli L, Dasseni N, Silverii MV, Albricci L, D'Ambrosio G, Garrì R, Esposito L, Giallauria F Abstract The present study aims at evaluating the achievement of blood pressure, lipid and blood glucose targets, healthy lifestyle changes and appropriate drug prescription/adherence in patients attending secondary prevention/CR ambulatory visit after index cardiovascular event in a time period ranging 1 to 5 year. At ambulatory visit, a predetermined set of data collection was used, including demographic data, cardiovascular risk factors and lifestyle habits, type and...
Source: Monaldi Archives for Chest Disease - May 22, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Pulmonary complications after elective coronary artery bypass grafting surgery in patients with and without sleep-disordered breathing - a prospective observational study
Conclusion: Amongst established risk factors for PPCs, central sleep apnoea was independently associated with MPCs.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Tafelmeier, M., Luft, L., Floerchinger, B., Camboni, D., Creutzenberg, M., Wittmann, S., Zeman, F., Schmid, C., Maier, L. S., Wagner, S., Arzt, M. Tags: Acute critical care Source Type: research

Early surgical myocardial revascularization in non-ST-segment elevation acute coronary syndrome.
Conclusions: Early revascularized patients showed a higher level of illness. However, results of early CABG were comparable to those following delayed revascularization. Moreover, EuroSCORE II was determined as independent risk factors for mortality. PMID: 31903232 [PubMed]
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Association of early elevated cardiac troponin I concentration and longitudinal change after off-pump coronary artery bypass grafting and adverse events: a prospective cohort study.
Conclusions: Longitudinal change in cTnI levels within 24 hours and early cTnI concentrations, even less than 1 hour after CABG, are associated with adverse events. These data will be useful in identifying patients at an increased risk of complications. PMID: 33282356 [PubMed]
Source: Journal of Thoracic Disease - December 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Beating-heart on-pump coronary artery bypass grafting < em > vs. < /em > off-pump coronary artery bypass grafting: a systematic review and meta-analysis
CONCLUSIONS: BH-ONCAB is a safe and comparable alternative to OPCAB in terms of early mortality and late survival. BH-ONCAB may confer particular advantages in preventing incomplete revascularization and allowing more distal anastomoses compared to OPCAB. However, BH-ONCAB was associated with more postoperative complications due to the use of CPB. Future work should focus on larger matched studies and multicenter randomized controlled trials to optimize our surgical revascularization strategies.PMID:34422347 | PMC:PMC8339796 | DOI:10.21037/jtd-21-268
Source: Journal of Thoracic Disease - August 23, 2021 Category: Respiratory Medicine Authors: Yefan Jiang Li Xu Yuqi Liu Bowen Deng Nianguo Dong Si Chen Source Type: research

Ninety-seven cases of experiences with the left thoracotomy approach for off-pump conventional revascularization: a retrospective cohort study
CONCLUSIONS: Left thoracotomy for conventional revascularization is a safe procedure for appropriately selected patients, with few early complications and good early and mid-term results. More cases are ongoing and long-term results are in observation.PMID:36389332 | PMC:PMC9641355 | DOI:10.21037/jtd-22-1162
Source: Journal of Thoracic Disease - November 17, 2022 Category: Respiratory Medicine Authors: Dongyan Yang Kai Zhang Junshan Li Dong Wei Jing Ma Yulong Wang Yin Yang Jinghui Li Yunpeng Bai Yuhui Zhang Jing Gao Lianqun Wang Source Type: research

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