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Procedure: Perfusion

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Total 2334 results found since Jan 2013.

Collateral-Core Ratio as a Novel Predictor of Clinical Outcomes in Acute Ischemic Stroke
AbstractThe interaction effect between collateral circulation and ischemic core size on stroke outcomes has been highlighted in acute ischemic stroke (AIS). However, biomarkers that assess the magnitude of this interaction are still lacking. We aimed to present a new imaging marker, the collateral-core ratio (CCR), to quantify the interaction effect between these factors and evaluate its ability to predict functional outcomes using machine learning (ML) in AIS. Patients with AIS caused by anterior circulation large vessel occlusion (LVO) were recruited from a prospective multicenter study. CCR was calculated as collateral ...
Source: Translational Stroke Research - July 25, 2022 Category: Neurology Source Type: research

Prognostic Value of Venous Outflow Profiles on Multiphase CT Angiography for the Patients with Acute Ischemic Stroke After Endovascular Thrombectomy
This study supports that favorable peak venous VO profiles on mCTA might be a promising biomarker in predicting the good outcome in patients with AIS after EVT.
Source: Translational Stroke Research - September 5, 2023 Category: Neurology Source Type: research

Leukoaraiosis and Sex Predict the Hyperacute Ischemic Core Volume Original Contributions
Conclusions— Severe LA and male sex are associated with larger infarct cores, which adds to the notion that sex and LA alter the brain’s intrinsic susceptibility to acute cerebral ischemia. Future, larger studies are needed to confirm our observation that women have smaller core volumes and its significance.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Henninger, N., Lin, E., Haussen, D. C., Lehman, L. L., Takhtani, D., Selim, M., Moonis, M. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke Original Contributions Source Type: research

Early microvascular dysfunction in cerebral small vessel disease is not detectable on 3.0 Tesla magnetic resonance imaging: a longitudinal study in spontaneously hypertensive stroke-prone rats
Conclusion Serial MRI at a field strength of 3 T failed to detect the initial microvascular dysfunction and subsequent small perivascular bleeds in SHRSP; only terminal stages of cerebral microangiopathy were reliably detected. Further investigations at higher magnetic field strengths (7 T) using blood- and flow-sensitive sequences are currently underway.
Source: Experimental and Translational Stroke Medicine - June 25, 2013 Category: Neurology Source Type: research

Intra-arterial Administration of Papaverine during Mechanical Thrombectomy for Acute Ischemic Stroke
The use of stent retrievers for mechanical thrombectomy in acute ischemic stroke may induce significant vasospasm, which at the early phases of reperfusion may be crucial for rethrombosis of the recanalized vessel. We aimed to study whether the use of intra-arterial papaverine in selected cases of vasospasm was associated with improved cerebral perfusion, arterial reocclusion, or increased hemorrhagic complications.
Source: Journal of Stroke and Cerebrovascular Diseases - November 13, 2014 Category: Neurology Authors: Gerasimos Baltsavias, Susmitha Yella, Rahman Abdul Al Shameri, Andreas Luft, Anton Valavanis Source Type: research

Using Standard First-Pass Perfusion Computed Tomographic Data to Evaluate Collateral Flow in Acute Ischemic Stroke Clinical Sciences
Conclusions— Ktrans maps extracted from standard first-pass perfusion computed tomography are correlated with collateral circulation status after acute proximal arterial occlusion and predictive of outcome.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Chen, H., Wu, B., Liu, N., Wintermark, M., Su, Z., Li, Y., Hu, J., Zhang, Y., Zhang, W., Zhu, G. Tags: Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Why are most stroke patients deemed poor candidates for intraaterial therapy? A prospective study (P4.306)
Conclusion: The majority of patients presenting to a large tertiary referral center with AIS due to a large vessel occlusion were found to be poor IA candidates, with more than half excluded for a single reason. Such data addressing the volume and proportion of patients found ineligible for IA therapy in real-world practice can help target efforts to develop new interventional options and improve future clinical trial design.Disclosure: Dr. Damania has nothing to disclose. Dr. Noto has nothing to disclose. Dr. Kung has nothing to disclose. Dr. Liew has nothing to disclose. Dr. Finley has nothing to disclose. Dr. Mangla has...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Damania, D., Noto, A., Kung, N., Liew, J., Finley, H., Mangla, R., Miranpuri, A., Sahin, B., Jahromi, B. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Interventional Treatment for Ischemic Stroke Source Type: research

Therapeutically Targeting Tumor Necrosis Factor-{alpha}/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage Basic Sciences
Conclusions— Vascular smooth muscle cell TNFα and sphingosine-1-phosphate signaling significantly enhance cerebral artery tone in SAH; anti-TNFα and anti–sphingosine-1-phosphate treatment may significantly improve clinical outcome.
Source: Stroke - July 27, 2015 Category: Neurology Authors: Yagi, K., Lidington, D., Wan, H., Fares, J. C., Meissner, A., Sumiyoshi, M., Ai, J., Foltz, W. D., Nedospasov, S. A., Offermanns, S., Nagahiro, S., Macdonald, R. L., Bolz, S.-S. Tags: Animal models of human disease, Acute Cerebral Hemorrhage, Brain Circulation and Metabolism, Other Stroke Treatment - Medical, Other Vascular biology Basic Sciences Source Type: research

Noninvasive cerebral oximetry during endovascular therapy for acute ischemic stroke: an observational study
Julian Bösel
Source: Journal of Cerebral Blood Flow - August 5, 2015 Category: Neurology Authors: Christian HametnerPredrag StanarcevicSibylle StampflStefan RohdeRoland VeltkampJulian Bösel Tags: acute ischemic stroke medial cerebral artery occlusion near-infrared spectroscopy perfusion regional oxygen saturation thrombectomy Source Type: research

Thrombus Length Estimation on Delayed Gadolinium-Enhanced T1 Clinical Sciences
Conclusions— The dGE-T1, obtained by simply adjusting scanning order in multimodal magnetic resonance imaging protocol, is a useful tool for thrombus length estimation and middle cerebral artery recanalization prediction after IVT.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Yan, S., Chen, Q., Xu, M., Sun, J., Liebeskind, D. S., Lou, M. Tags: Angiography, Ischemic Stroke Clinical Sciences Source Type: research

Stroke Presentation of Acute Type A Aortic Dissection with 100% Perfusion-Weighted Imaging–Diffusion-Weighted Imaging Mismatch: A Call for Urgent Action
Acute stroke in the setting of acute type A aortic dissection is not rare and may contraindicate immediate surgery. Evaluating irreversible brain damage is critical in this setting and magnetic resonance imaging is a key determinant in the decision of selecting surgical over medical treatment for these patients.
Source: Journal of Stroke and Cerebrovascular Diseases - March 7, 2016 Category: Neurology Authors: Gilles Amr, Gregoire Boulouis, Nicolas Bricout, Thomas Modine, Georges Fayad, Pierre Aguettaz, Mohamad Koussa Tags: Case Studies Source Type: research

Patient selection for stroke thrombectomy: Is CT head good enough?
Six randomized controlled trials have established the substantial benefit of mechanical thrombectomy for acute ischemic stroke patients presenting with large vessel occlusive disease.1–6 Enrolling patients with large clinical deficit in the setting of small completed infarct and rapid, complete, or near complete recanalization, and treatment with the most recent generation of thrombectomy devices, contributed to this success. Efforts to generalize the results of these trials beyond select, experienced centers have focused attention on workflow and developing consensus on patient selection. Optimizing outcomes require...
Source: Neurology - July 17, 2016 Category: Neurology Authors: Jadhav, A. P., Wechsler, L. R. Tags: CT, All Cerebrovascular disease/Stroke, Infarction EDITORIALS Source Type: research

Different Perfusion Patterns in a Patient with Acute Ischemic Stroke
A 29-year-old male patient with aphasia and mild weakness of the right arm arrived at the emergency room 4 hours after symptom onset. The computed tomography perfusion showed a typical delay in the time-based maps in the left occipital lobe and another hyperperfused area in the left frontal lobe. The follow-up magnetic resonance imaging confirmed cortical ischemic lesions in both areas. This case shows that besides hypoperfusion, hyperperfusion can also be found in the first stages of acute stroke, and it is highly suggestive of established ischemic lesions.
Source: Journal of Stroke and Cerebrovascular Diseases - March 9, 2017 Category: Neurology Authors: Salvatore Rudilosso, Carlos Laredo, Xabier Urra, Ángel Chamorro Tags: Case Studies Source Type: research

Absent Filling of Ipsilateral Superficial Middle Cerebral Vein Is Associated With Poor Outcome After Reperfusion Therapy Clinical Sciences
Conclusions—Lack of SMCV filling contributed to poor outcome after thrombolysis, especially when reperfusion was not achieved. The main deleterious effect of poor venous filling appears related to the development of brain edema.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Sheng Zhang, Yangxiao Lai, Xinfa Ding, Mark Parsons, John H. Zhang, Min Lou Tags: Cerebrovascular Disease/Stroke Original Contributions Source Type: research