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Total 3622 results found since Jan 2013.

Cerebral microbleeds and the risk of intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: systematic review and meta-analysis
Conclusions The available evidence does not demonstrate a statistically significant increased risk of symptomatic ICH after thrombolysis for ischaemic stroke in patients with CMBs. However, in view of the methodological limitations of the studies included, the clinical relevance of any potential hazard associated with CMBs remains uncertain. Further studies are warranted to evaluate whether the risk of ICH might outweigh the benefit of thrombolysis, especially in patients with multiple lobar CMBs suggestive of cerebral amyloid angiopathy.
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 15, 2013 Category: Neurosurgery Authors: Charidimou, A., Kakar, P., Fox, Z., Werring, D. J. Tags: Genetics, Stroke, Radiology, Radiology (diagnostics) Cerebrovascular disease Source Type: research

Thrombolysis for acute ischemic stroke in South Africa
ConclusionsOur findings indicate that the use of thrombolysis in routine clinical practice in a South African setting has similar safety and early efficacy outcomes to developed and other developing countries.
Source: International Journal of Stroke - May 22, 2013 Category: Neurology Authors: Alan Bryer, Sean Wasserman Tags: Short Report Source Type: research

Incidence of Venous Thromboembolism in the Wake of the Clots in Legs Or sTockings after Stroke (CLOTS) Study Brief Reports
Conclusions— Discontinuation of compressive stockings did not increase venous thromboembolism incidence. There was a trend toward more deep vein thrombosis and fewer PEs after CLOTS, which might be because of increased clinical vigilance in the diagnosis of deep vein thrombosis, but a chance variation cannot be excluded.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Jain, P., Ward, E., Nevatte, T., Roffe, C. Tags: Deep vein thrombosis Brief Reports Source Type: research

Diffusion mr correlates of motor function recovery after stroke: a systematic review
Conclusions FA is the most commonly measured metric but there was considerable heterogeneity in study design and analysis. Most studies were cross–sectional, confined to sub–cortical, ischaemic strokes at late stages, and involved younger patients than typical of the stroke population. Further evaluation of the utility of DTI as a biomarker for use in stroke recovery trials is needed.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Kalladka, D., Muir, K. Tags: Stroke, Radiology, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

The halifax acute stroke imaging study (hasis): does ct perfusion scanning in acute ischemic stroke predict final infarct volume?
Conclusions Results from HASIS suggest information from admission CTP and SI in suspected AIS patients can predict final infarct volume, where final volume of infarcted brain will not be smaller than that predicted by CTP CBV or CTA SI.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Langlands, G., Shankar, J., Simpkin, W., Christian, C., Phillips, S. Tags: Stroke, Radiology, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Alberta Stroke Program Early Computed Tomography Score to Select Patients for Endovascular Treatment: Interventional Management of Stroke (IMS)-III Trial Clinical Sciences
Conclusions— ASPECTS is a strong predictor of outcome and a predictor of reperfusion. ASPECTS did not identify a subpopulation of subjects that particularly benefitted from endovascular therapy immediately after routine intravenous tPA. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00359424.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Hill, M. D., Demchuk, A. M., Goyal, M., Jovin, T. G., Foster, L. D., Tomsick, T. A., von Kummer, R., Yeatts, S. D., Palesch, Y. Y., Broderick, J. P., for the IMS3 Investigators Tags: Angiography, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis, Angioplasty and Stenting Clinical Sciences Source Type: research

Six-Minute Magnetic Resonance Imaging Protocol for Evaluation of Acute Ischemic Stroke: Pushing the Boundaries Clinical Sciences
Conclusions— A 6-minute multimodal MR protocol with good diagnostic quality is feasible for the evaluation of patients with acute ischemic stroke and can result in significant reduction in scan time rivaling that of the multimodal computed tomographic protocol.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Nael, K., Khan, R., Choudhary, G., Meshksar, A., Villablanca, P., Tay, J., Drake, K., Coull, B. M., Kidwell, C. S. Tags: CT and MRI, Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Atrial Fibrillation and Cognitive Decline-The Role of Subclinical Cerebral Infarcts: The Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— The association of incident AF with cognitive decline in stroke-free individuals can be explained by the presence or development of SCIs, raising the possibility of anticoagulation as a strategy to prevent cognitive decline in AF.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Chen, L. Y., Lopez, F. L., Gottesman, R. F., Huxley, R. R., Agarwal, S. K., Loehr, L., Mosley, T., Alonso, A. Tags: Cerebrovascular disease/stroke, Arrhythmias, clinical electrophysiology, drugs, Computerized tomography and Magnetic Resonance Imaging, Epidemiology Clinical Sciences Source Type: research

Intra-Arterial Therapy and Post-Treatment Infarct Volumes: Insights From the ESCAPE Randomized Controlled Trial Clinical Sciences
Conclusions— These results support the primary results of the ESCAPE trial and show that the biological underpinning of the success of endovascular therapy is a reduction in infarct volume. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01778335.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Al-Ajlan, F. S., Goyal, M., Demchuk, A. M., Minhas, P., Sabiq, F., Assis, Z., Willinsky, R., Montanera, W. J., Rempel, J. L., Shuaib, A., Thornton, J., Williams, D., Roy, D., Poppe, A. Y., Jovin, T. G., Sapkota, B. L., Baxter, B. W., Krings, T., Silver, F Tags: Imaging, Quality and Outcomes, Ischemic Stroke Clinical Sciences Source Type: research

Neuroimaging Markers of Cognitive Outcome in Children with Perinatal Stroke (I2.002)
Conclusions: As seen in other studies, prognosis of cognitive outcome is difficult and there was no correlation between site of lesion and areas of intellectual deficit. However, there was some indication that loss of more cortical volume, or involvement of the DLPF cortex may be risk factors for intellectual impairment in childhood.Disclosure: Dr. Murias has nothing to disclose. Dr. Kirton has nothing to disclose. Dr. Tariq has nothing to disclose. Dr. Moir has nothing to disclose. Dr. Iaria has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Murias, K., Kirton, A., Tariq, S., Moir, A., Iaria, G. Tags: Stroke in the Elderly and Young: Challenges for the Next Decade Data Blitz Presentations Source Type: research

Neuroimaging Markers of Cognitive Outcome in Children with Perinatal Stroke (P3.256)
Conclusions: As seen in other studies, prognosis of cognitive outcome is difficult and there was no correlation between site of lesion and areas of intellectual deficit. However, there was some indication that loss of more cortical volume, or involvement of the DLPF cortex may be risk factors for intellectual impairment in childhood.Disclosure: Dr. Murias has nothing to disclose. Dr. Kirton has nothing to disclose. Dr. Tariq has nothing to disclose. Dr. Moir has nothing to disclose. Dr. Iaria has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Murias, K., Kirton, A., Tariq, S., Moir, A., Iaria, G. Tags: Child Neurology and Developmental Neurology: Epilepsy, Hypoxia, and Stroke Source Type: research

Multidisciplinar Team Ability to Decrease Door-To-Needle Time in Acute Ischemic Stroke - A Single Center Saudi Experience (P6.053)
Conclusions: Implementation of modified stroke code process utilizing quality improvement paradigm of PDSA cycles have resulted in significant decrease in door-to-needle time for IV thrombolysis. Although, the target DTN of 60 minutes was not reached, the trend is favorable with improved outcomes. Disclosure: Partly presented at 5th Annual KAIMRC Forum, September, 2014, Jeddah, Saudi ArabiaDisclosure: Dr. Khatri has nothing to disclose. Dr. Khathaami has nothing to disclose. Dr. Alhamouieh has nothing to disclose. Dr. Abulaban has nothing to disclose. Dr. Scriven has nothing to disclose. Dr. Tarawneh has nothing to disclos...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Khatri, I., Khathaami, A., Alhamouieh, O., Abulaban, A., Scriven, S., Tarawneh, M., Alrasheed, D., AlSomali, S., Catangui, E., Manalili, C., Ghadalla, A., Alanizi, A., Kojan, S. Tags: Prehospital Stroke Care and Uses of NIHSS Source Type: research

Evolutional Characterization of Photochemically Induced Stroke in Rats: a Multimodality Imaging and Molecular Biological Study
In conclusion, these characterizations may be highly beneficial to the development of therapeutic strategies for ischemi c stroke.
Source: Translational Stroke Research - November 30, 2016 Category: Neurology Source Type: research

Prediction of Blood-Brain Barrier Disruption and Intracerebral Hemorrhagic Infarction Using Arterial Spin-Labeling Magnetic Resonance Imaging Clinical Sciences
Background and Purpose—Arterial spin-labeling magnetic resonance imaging is sensitive for detecting hyperemic lesions (HLs) in patients with acute ischemic stroke. We evaluated whether HLs could predict blood–brain barrier (BBB) disruption and hemorrhagic transformation (HT) in acute ischemic stroke patients.Methods—In a retrospective study, arterial spin-labeling was performed within 6 hours of symptom onset before revascularization treatment in 25 patients with anterior circulation large vessel occlusion on baseline magnetic resonance angiography. All patients underwent angiographic procedures intended for endovasc...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Takeya Niibo, Hajime Ohta, Shirou Miyata, Ichiro Ikushima, Kazuchika Yonenaga, Hideo Takeshima Tags: Imaging, Magnetic Resonance Imaging (MRI), Blood-Brain Barrier, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Streamlining door to recanalization processes in endovascular stroke therapy
Conclusions This pilot study demonstrates that D2P times can be significantly reduced with a standardized multidisciplinary approach. There was no significant difference in the rate of 3-month good outcome, which is most likely due to the small sample size and confounding baseline patient characteristics.
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Aghaebrahim, A., Streib, C., Rangaraju, S., Kenmuir, C. L., Giurgiutiu, D.-V., Horev, A., Saeed, Y., Callaway, C. W., Guyette, F. X., Martin-Gill, C., Pacella, C., Ducruet, A. F., Jankowitz, B. T., Jovin, T. G., Jadhav, A. P. Tags: Ischemic stroke Source Type: research