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Procedure: Perfusion

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Total 2334 results found since Jan 2013.

Worse stroke outcome in atrial fibrillation is explained by more severe hypoperfusion, infarct growth, and hemorrhagic transformation
ConclusionAtrial fibrillation is associated with greater volumes of more severe baseline hypoperfusion, leading to higher infarct growth, more frequent severe hemorrhagic transformation and worse stroke outcomes.
Source: International Journal of Stroke - March 12, 2013 Category: Neurology Authors: Hans T. H. Tu, Bruce C. V. Campbell, Soren Christensen, Patricia M. Desmond, Deidre A. De Silva, Mark W. Parsons, Leonid Churilov, Maarten G. Lansberg, Michael Mlynash, Jean‐Marc Olivot, Matus Straka, Roland Bammer, Gregory W. Albers, Geoffrey A. Donnan Tags: Research Source Type: research

Impaired perfusion modifies the relationship between blood pressure and stroke risk in major cerebral artery disease
Conclusions Impaired perfusion modified the relationship between blood pressure and stroke risk, although this study had limitations including the retrospective analysis, the potentially biased sample, the small number of critical events and the fact that BP was measured only as a snapshot in clinic.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Yamauchi, H., Higashi, T., Kagawa, S., Kishibe, Y., Takahashi, M. Tags: Open access, Stroke, Hypertension, Radiology, Radiology (diagnostics) Cerebrovascular disease Source Type: research

Stroke Lesion Volumes and Outcome Are Not Different in Hemispheric Stroke Side Treated With Intravenous Thrombolysis Based on Magnetic Resonance Imaging Criteria Clinical Sciences
Conclusions— We did not find differences between RHS and left HS with regards to stroke lesions volumes or outcome after thrombolysis. Previously reported hemisphere-related differences in stroke outcome may partly results from imbalances in stroke lesion volume between RHS and left HS.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Golsari, A., Cheng, B., Sobesky, J., Schellinger, P. D., Fiehler, J., Gerloff, C., Thomalla, G. Tags: Acute Cerebral Infarction, Thrombolysis Clinical Sciences Source Type: research

Eligibility for Endovascular Trial Enrollment in the 6- to 24-Hour Time Window Brief Report
Conclusions—Of all patients with acute ischemic stroke presenting to a single comprehensive stroke center, 1.7% of patients qualified for DAWN clinical trial enrollment with an additional 0.6% to 1% qualifying for the DEFUSE-3 trial. These data predict an increase in thrombectomy utilization with important implications for comprehensive stroke center resource optimization and stroke systems of care.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Ashutosh P. Jadhav, Shashvat M. Desai, Cynthia L. Kenmuir, Marcelo Rocha, Matthew T. Starr, Bradley J. Molyneaux, Bradley A. Gross, Brian T. Jankowitz, Tudor G. Jovin Tags: Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Brief Reports Source Type: research

Prognostic Evaluation Based on Cortical Vein Score Difference in Stroke Clinical Sciences
Conclusions— The Prognostic Evaluation based on Cortical vein score difference In Stroke score, a novel measure of venous enhancement on CT angiography, accurately predicts clinical outcomes. Venous features on computed tomography angiography provide additional characterization of collateral perfusion and prognostication in acute ischemic stroke.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Parthasarathy, R., Kate, M., Rempel, J. L., Liebeskind, D. S., Jeerakathil, T., Butcher, K. S., Shuaib, A. Tags: Acute Cerebral Infarction, Brain Circulation and Metabolism, Angiography, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Protocol for the perfusion and angiography imaging sub‐study of the Third International Stroke Trial (IST‐3) of alteplase treatment within six‐hours of acute ischemic stroke
RationaleIntravenous thrombolysis with recombinant tissue Plasminogen Activator improves outcomes in patients treated early after stroke but at the risk of causing intracranial hemorrhage. Restricting recombinant tissue Plasminogen Activator use to patients with evidence of still salvageable tissue, or with definite arterial occlusion, might help reduce risk, increase benefit and identify patients for treatment at late time windows. AimsTo determine if perfusion or angiographic imaging with computed tomography or magnetic resonance help identify patients who are more likely to benefit from recombinant tissue Plasminogen Ac...
Source: International Journal of Stroke - January 22, 2013 Category: Neurology Authors: Joanna M. Wardlaw, Rudiger Kummer, Trevor Carpenter, Mark Parsons, Richard I. Lindley, Geoff Cohen, Veronica Murray, Adam Kobayashi, Andre Peeters, Francesca Chappell, Peter A. G. Sandercock Tags: Protocols Source Type: research

Ct perfusion in acute ischaemic stroke: do we cover the lesion and what does it mean?
Conclusions Even with limited z–directional coverage CTP is more sensitive than NCCT ASPECTS scoring to detect evidence of acute stroke. In this cohort CTP acquisition at the basal ganglia was more often too inferior than it was too superior to maximise lesion coverage. Patients without perfusion deficits have better functional outcomes than those with perfusion deficits.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Collins, P., Dani, K., Moreton, F., McVerry, F., MacDougall, N., Macleod, M. J., Wardlaw, J., Muir, K. Tags: Stroke Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Initial Experience with Upfront Arterial and Perfusion Imaging among Ischemic Stroke Patients Presenting within the 4.5-hour Time Window
Conclusions: An upfront CTA/CTP protocol aided stroke team decision-making in nearly half of cases. Implementation of a CTA/CTP protocol was associated with a learning curve of 6 months before door to needle time ≤60 minutes returned to similar rates as the pre-CTA/CTP protocol.
Source: Journal of Stroke and Cerebrovascular Diseases - January 24, 2013 Category: Neurology Authors: Ali Reza Noorian, Katja Bryant, Ashley Aiken, Andrew D. Nicholson, Adam B. Edwards, Mason P. Markowski, Seena Dehkharghani, Jemisha C. Bouloute, Jacquelyn Abney, Fadi Nahab Tags: Original Articles Source Type: research

Role of atherosclerosis, clot extent, and penumbra volume in headache during ischemic stroke
Conclusions: Headache in the early phase of ischemic stroke tends to occur less often in patients with atherosclerosis than in patients without atherosclerosis in the large cerebral arteries. This finding lends support to the hypothesis that vessel wall elasticity is a necessary contributing factor in the occurrence of headache during acute ischemic stroke.
Source: Neurology - September 11, 2016 Category: Neurology Authors: van Os, H. J. A., Mulder, I. A., van der Schaaf, I. C., Kappelle, L. J., Velthuis, B. K., Broersen, A., Vos, J. A., Terwindt, G. M., Schonewille, W., Ferrari, M. D., Algra, A., van Walderveen, M. A. A., Wermer, M. J. H. Tags: All Headache, CT, All Clinical Neurology, All Cerebrovascular disease/Stroke, Infarction ARTICLE Source Type: research

High values of baseline and 24-hour Mean Arterial Pressure are associated with lower chance of early neurological improvement in acute stroke patients treated with thrombolysis (P4.286)
Conclusions:High baseline and 24-hr MAP values are associated with lower chance of achieving ENI after IV thrombolysis. Further studies are needed to better understand whether acute BP dysregulation can influence different clinical courses in the early phase of IV thrombolysis.Disclosure: Dr. Lorenzano has nothing to disclose. Dr. Caselli has nothing to disclose. Dr. Zingaro has nothing to disclose. Dr. Orlando has nothing to disclose. Dr. Toni has received research support from Bayer, Medtronic, and Boehriger Ingelheim.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Lorenzano, S., Caselli, M. C., Zingaro, A., Orlando, F., Toni, D. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Endovascular treatment beyond 24 hours from the onset of acute ischemic stroke: the Italian Registry of Endovascular Thrombectomy in Acute Stroke (IRETAS)
Conclusions These findings suggest that, in a real world setting, very late endovascular therapy is feasible in appropriately selected patients.
Source: Journal of NeuroInterventional Surgery - November 14, 2022 Category: Neurosurgery Authors: Casetta, I., Fainardi, E., Pracucci, G., Saia, V., Vallone, S., Zini, A., Bergui, M., Cerrato, P., Nappini, S., Nencini, P., Gasparotti, R., Saletti, A., Causin, F., Romano, D., Burdi, N., Giorgianni, A., Mangiafico, S., Toni, D., The Italian Registry of Tags: Ischemic stroke Source Type: research

Safety and Effectiveness of Endovascular Treatment after 6 Hours of Symptom Onset in Patients with Anterior Circulation Ischemic Stroke: A Matched Case Control Study
Conclusions: We did not observe any evidence of benefit in halting neurologic worsening or improving outcomes among patients undergoing endovascular treatment for treatment of an anterior circulation ischemic stroke after 6 hours of symptom onset. Strong evidence of both the safety and efficacy of emergent endovascular treatment when administered to patients with stroke in the anterior circulation is needed.
Source: Journal of Stroke and Cerebrovascular Diseases - October 24, 2012 Category: Neurology Authors: Adnan I. Qureshi, Jefferson T. Miley, Saqib A. Chaudhry, Edouard Semaan, Gustavo J. Rodriguez, M.Fareed K. Suri, Harold P. Adams Tags: Original Articles Source Type: research

Optical Bedside Monitoring of Cerebral Blood Flow in Acute Ischemic Stroke Patients during Head of Bed Manipulation (P4.216)
CONCLUSIONS: A lower HOB angle results in an increase in cortical CBF without a significant change in arterial flow velocity in the setting of acute stroke, but there is variability across patients in this response. Bedside CBF monitoring with DCS provides a potential means to individualize interventions designed to optimize CBF in acute ischemic stroke.Disclosure: Dr. Favilla has nothing to disclose. Dr. Mesquita has nothing to disclose. Dr. Mullen has nothing to disclose. Dr. Durduran has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Minkoff has nothing to disclose. Dr. Kasner has received personal compensati...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Favilla, C., Mesquita, R., Mullen, M., Durduran, T., Kim, M., Minkoff, D., Kasner, S., Joel, G., Yodh, A., Detre, J. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Endovascular Source Type: research

Solitaire™ with the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke (SWIFT PRIME) trial: protocol for a randomized, controlled, multicenter study comparing the Solitaire revascularization device with IV tPA with IV tPA alone in acute ischemic stroke
RationaleEarly reperfusion in patients experiencing acute ischemic stroke is critical, especially for patients with large vessel occlusion who have poor prognosis without revascularization. Solitaire™ stent retriever devices have been shown to immediately restore vascular perfusion safely, rapidly, and effectively in acute ischemic stroke patients with large vessel occlusions. AimThe aim of the study was to demonstrate that, among patients with large vessel, anterior circulation occlusion who have received intravenous tissue plasminogen activator, treatment with Solitaire revascularization devices reduces degree of disab...
Source: International Journal of Stroke - March 16, 2015 Category: Neurology Authors: Jeffrey L. Saver, Mayank Goyal, Alain Bonafe, Hans‐Christoph Diener, Elad I. Levy, Vitor M. Pereira, Gregory W. Albers, Christophe Cognard, David J. Cohen, Werner Hacke, Olav Jansen, Tudor G. Jovin, Heinrich P. Mattle, Raul G. Nogueira, Adnan H. Siddiqu Tags: Protocols Source Type: research

Additional Diagnostic Value of Computed Tomography Perfusion for Detection of Acute Ischemic Stroke in the Posterior Circulation Brief Reports
Conclusions— CT perfusion has significant additional diagnostic values to noncontrast CT and CT angiography source images for detecting ischemic changes in patients suspected of acute posterior circulation stroke.
Source: Stroke - March 23, 2015 Category: Neurology Authors: van der Hoeven, E. J. R. J., Dankbaar, J. W., Algra, A., Vos, J. A., Niesten, J. M., van Seeters, T., van der Schaaf, I. C., Schonewille, W. J., Kappelle, L. J., Velthuis, B. K., on behalf of the DUST Investigators Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging Brief Reports Source Type: research