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Total 641 results found since Jan 2013.

Neurosurgery Morbidity and Mortality: A Prospective Surgical and Medical Analysis
CONCLUSION: The mortality and morbidity analysis provided valuable neurosurgical information that may influence future treatment management and corrective recommendations. Indication and judgment errors were significantly associated with mortality. In our study, the patients' comorbidities were not significant for mortality or increased length of stay.PMID:36941096
Source: Puerto Rico Health Sciences Journal - March 20, 2023 Category: International Medicine & Public Health Authors: Orlando De Jesus Jos é I Sandoval-Consuegra Aixa De Jes ús-Espinosa Ricardo J Fern ández-de Thomas C ésar M Carballo-Cuello Source Type: research

Molecules, Vol. 28, Pages 2598: Gastrodin and Gastrodigenin Improve Energy Metabolism Disorders and Mitochondrial Dysfunction to Antagonize Vascular Dementia
This study explored the effects of Gas and HBA on cognitive dysfunction in VD and their possible molecular mechanisms. The VD model was established by bilateral common carotid artery ligation (2-vessel occlusion, 2-VO) combined with an intraperitoneal injection of sodium nitroprusside solution. One week after modeling, Gas (25 and 50 mg/kg, i.g.) and HBA (25 and 50 mg/kg, i.g.) were administered orally for four weeks, and the efficacy was evaluated. A Morris water maze test and passive avoidance test were used to observe their cognitive function, and H&E staining and Nissl staining were used to observe the neur...
Source: Molecules - March 13, 2023 Category: Chemistry Authors: Sha Wu Rong Huang Ruiqin Zhang Chuang Xiao Lueli Wang Min Luo Na Song Jie Zhang Fang Yang Xuan Liu Weimin Yang Tags: Article Source Type: research

Long ‐term outcomes in heart failure with preserved ejection fraction: Predictors of cardiac and non‐cardiac mortality
ConclusionsIn patients with acute decompensated HFpEF, over 5  years of follow-up, nearly of patients died, half from CV and the other half from non-CV causes. CAD and tricuspid regurgitation were associated with CV death. Stroke, kidney disease, lower BMI, and lower sodium were associated with non-CV death. Anaemia and higher age were associated with both ou tcomes.
Source: ESC Heart Failure - March 11, 2023 Category: Cardiology Authors: Angiza Shahim, Marion Hourqueig, Lars H. Lund, Gianluigi Savarese, Emmanuel Oger, Ashwin Venkateshvaran, Lina Benson, Jean ‐Claude Daubert, Cecilia Linde, Erwan Donal, Camilla Hage Tags: Original Article Source Type: research

Glucagon-Like Peptide 1 Receptor Agonists Versus Sodium-Glucose Cotransporter 2 Inhibitors for Atherosclerotic Cardiovascular Disease in Patients With Type 2 Diabetes
Cardiol Res. 2023 Feb;14(1):12-21. doi: 10.14740/cr1459. Epub 2023 Feb 25.ABSTRACTBeyond improving hemoglobin A1c (HbA1c) in adults with type 2 diabetes, glucagon-like peptide 1 receptor agonists (GLP-1RA) have been approved for reducing risk of major adverse cardiovascular events (MACE) with established cardiovascular disease (CVD) or multiple CV risk factors. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) also reduced the risk for the primary composite CV outcome in patients with type 2 diabetes at high risk for CV events. In the American Diabetes Association (ADA) and European Association of Study in Diabetes (EASD)...
Source: Atherosclerosis - March 10, 2023 Category: Cardiology Authors: Hidekatsu Yanai Hiroki Adachi Mariko Hakoshima Hisayuki Katsuyama Source Type: research