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More Research Is Needed on Lifestyle Behaviors That Influence Progression of Parkinson's Disease
This article highlights some of these challenges in the design of lifestyle studies in PD, and suggests a more coordinated international effort is required, including ongoing longitudinal observational studies. In combination with pharmaceutical treatments, healthy lifestyle behaviors may slow the progression of PD, empower patients, and reduce disease burden. For optimal care of people with PD, it is important to close this gap in current knowledge and discover whether such associations exist. Introduction Parkinson's disease (PD) is an age-related complex progressive neurodegenerative disorder, with key p...
Source: Frontiers in Neurology - April 29, 2019 Category: Neurology Source Type: research

Effect of intranasal administration of caffeine on mPFC ischemia ‑induced cognitive impairment in BALB/c mice
Acta Neurobiol Exp (Wars). 2022;82(3):295-303. doi: 10.55782/ane-2022-028.ABSTRACTCaffeine is a psychoactive compound used widely to enhance cognitive functions in human or animal studies. The present study examined the effects of caffeine on cognitive performance and inflammatory factors in mice with medial prefrontal cortex (mPFC) ischemia. Mice underwent a photothrombotic mPFC ischemic stroke and were treated with normal saline or caffeine at different doses intranasally for 7 days. The sham surgery animals received normal saline intranasally. The Morris water maze test and social interaction test were performed to asse...
Source: Acta Neurobiologiae Experimentalis - October 10, 2022 Category: Neurology Authors: Fatemeh Farokhi-Sisakht Mehdi Farhoudi Javad Mahmoudi Fereshteh Farajdokht Rana Kahfi-Ghaneh Saeed Sadigh-Eteghad Source Type: research

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