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Total 1059 results found since Jan 2013.

What Are Underlying Risk Factors for Liver Abscesses?
This study specific excluded patients with ALA or candidemia. LA treatment is usually antibiotics and less invasive surgical techniques such as aspiration or percutaneous catheter drainage, but other treatment including resection is sometimes needed Overall mortality from LA has decreased from 15-40% to as low as 0.8% in the pediatric populations as noted above. Learning Point LA can occur solely because of exposure to infectious organisms but is also commonly associated with hepatobiliary pathology as well. In Northern India study, the “[m]ajority of …children had no predisposing factors for development of LA ...
Source: PediatricEducation.org - August 21, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Cases of Tick-Borne Illnesses Are on the Rise. Some Experts Believe Climate Change is the Cause
(NEW YORK) — In 2022, doctors recorded the first confirmed case of tick-borne encephalitis virus acquired in the United Kingdom. It began with a bike ride. [time-brightcove not-tgx=”true”] A 50-year-old man was mountain biking in the North Yorkshire Moors, a national park in England known for its vast expanses of woodland and purple heather. At some point on his ride, at least one black-legged tick burrowed into his skin. Five days later, the mountain biker developed symptoms commonly associated with a viral infection — fatigue, muscle pain, fever. At first, he seemed to be on the mend, bu...
Source: TIME: Health - July 28, 2023 Category: Consumer Health News Authors: ZOYA TEIRSTEIN / Grist/AP Tags: Uncategorized climate change healthscienceclimate wire Source Type: news

‘Win-win-win’ strategy reduces dangerous parasite infections in African villages
Tiny parasites can have huge consequences. Flatworms belonging to the genus Schistosoma infect hundreds of millions of people worldwide, causing pain and weakness, stunting the growth and cognitive development of children, and, in some people, leading to liver disease or cancer. Now, researchers have shown in a trial in Senegal that a simple intervention could reduce the risk of infection and break the resulting spiral of poverty and disease. When they removed from local rivers or lakes the aquatic plants that help the snails hosting the worms thrive, that slashed the rates of schistosomiasis, as the parasitic infect...
Source: Science of Aging Knowledge Environment - July 12, 2023 Category: Geriatrics Source Type: research

Blastocystis sp. reduces the efficacy of 5-fluorouracil as a colorectal cancer chemotherapeutic treatment
In this study, we explored the in vitro and in vivo effects of Blastocystis on the activity of a commonly used CRC chemotherapeutic agent, 5-FU. The cellular and molecular effects of solubilized antigen of Blastocystis in the presence of 5-FU were investigated using HCT116, human CRC cell line and CCD 18-Co, normal human colon fibroblast cells. For the in vivo study, 30 male Wistar rats were divided into six groups, as follows; Control Group: oral administration of 0.3ml Jones' medium, Group A: rats injected with azoxymethane (AOM), Group A-30FU: Rats injected with AOM and administered 30mg/kg 5-FU, Group B-A-30FU: rats in...
Source: Experimental Parasitology - June 12, 2023 Category: Parasitology Authors: Vinoth Kumarasamy Umah Rani Kuppusamy Pailoor Jayalakshmi Suresh Kumar Govind Source Type: research

Lupeol Acetate and α-Amyrin Terpenes Activity against < em > Trypanosoma cruzi < /em > : Insights into Toxicity and Potential Mechanisms of Action
CONCLUSIONS: The present study proposes a rational approach for exploring lupeol acetate and α-amyrin terpene compounds to design new drugs candidates for Chagas disease.PMID:37235311 | PMC:PMC10220761 | DOI:10.3390/tropicalmed8050263
Source: Molecular Medicine - May 26, 2023 Category: Molecular Biology Authors: Daniel Pardo-Rodriguez Andres Cifuentes-L ópez Juan Bravo-Espejo Ibeth Romero Jorge Robles Claudia Cuervo Sol M Mej ía Jair Tellez Source Type: research

Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae)
This study provides insights into the evolution and activity of venom toxins in Limacodidae, and provides a platform for future structure-function characterisation of A.stimulea peptide toxins.PMID:37201876 | DOI:10.1016/j.bcp.2023.115598
Source: Biochemical Pharmacology - May 18, 2023 Category: Drugs & Pharmacology Authors: Mohaddeseh H Goudarzi David A Eagles Junxian Lim Kimberley A Biggs Andrew C Kotze Angela P Ruffell David P Fairlie Glenn F King Andrew A Walker Source Type: research

Prevalence and Associated Risk Factors of Intestinal Parasites among Children under Five Years of Age Attended at Bachuma Primary Hospital, West Omo Zone, Southwest Ethiopia: A Cross-Sectional Study
CONCLUSION: In this study, the prevalence of intestinal parasites recorded was low. Rural residency, absence of child hand washing practice before meal, and not trimming fingernail were among factors significantly associated with intestinal parasite infection.PMID:37187704 | PMC:PMC10181902 | DOI:10.1155/2023/2268554
Source: Journal of Tropical Medicine - May 15, 2023 Category: Tropical Medicine Authors: Tadesse Duguma Teshale Worku Samuel Sahile Daniel Asmelash Source Type: research