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Clinical recovery from stroke lesions and related outcomes
This study investigated stroke lesions in terms of clinical recovery and related outcomes. Twenty-seven stroke patients were assessed via longitudinal observational study. Brain lesions were evaluated using MRI. The Fugl-Meyer Assessment and clinical evaluations were performed monthly between 1 and 6months after onset. The anterior limb (ICAL) and genu (ICG) of the internal capsule were associated with recovery of the upper limbs in chronic stroke patients. Involvement of the anterior half of the middle third of the corona radiata, the ICAL, the ICG, and the caudate nucleus were related to recovery of the lower limbs. Invo...
Source: Journal of Clinical Neuroscience - December 17, 2016 Category: Neuroscience Source Type: research

Evaluating the effect of hydrocephalus cause on the manner of changes in the effective parameters and clinical symptoms of the disease
Publication date: January 2017 Source:Journal of Clinical Neuroscience, Volume 35 Author(s): Seifollah Gholampour, Nasser Fatouraee, Amir Saeed Seddighi, Afsoun Seddighi In the present study, the heads of 11 normal subjects and 21 patients affected by hydrocephalus due to three different causes were simulated using fluid–structure interaction (FSI). To validate the results, the calculated diagram of CSF velocity in aqueduct of Sylvius (AS) was compared with the similar velocity diagram measured using Cine PC-MRI for the same subject. After ensuring the agreement of results, other outputs such as CSF pressure were calcul...
Source: Journal of Clinical Neuroscience - December 14, 2016 Category: Neuroscience Source Type: research

Intravascular lymphoma mimicking vasculitis
This report documents the presence of intravascular lymphoma diagnosed on a brain biopsy in a 60-year-old man. He initially presented 6months before brain biopsy with chest pain and hypotension, warranting coronary artery bypass graft surgery. Four months later, he presented with signs attributed to a stroke (diaphoresis, slumped over in a chair and left hand weakness). He subsequently developed a sudden onset wide-based gait, left leg numbness, word finding difficulties and worsening confusion. A MRI study showed multiple infarcts in the brain, including cerebellum. Invasive angiogram suggested vasculitis. He was started ...
Source: Journal of Clinical Neuroscience - November 10, 2016 Category: Neuroscience Source Type: research

High-sensitivity C-reactive protein in stroke patients – The importance in consideration of influence of multiple factors in the predictability for disease severity and death
Publication date: Available online 4 November 2016 Source:Journal of Clinical Neuroscience Author(s): Hong Yu, Yue Huang, XinYu Chen, WenBao Nie, YongJun Wang, Yan Jiao, Guy L. Reed, Weikuan Gu, Hong Chen High sensitivity C-reactive protein (hsCRP) has been evaluated as a biomarker in stroke and relevant pathological diseases. While its predictive values in several pathological phenotypes have been confirmed, controversy exists among different studies. This review summarizes reports of the predictive values of hsCRP for the diagnosis, etiology, prognosis and mortality of stroke diseases. The current literature suggests th...
Source: Journal of Clinical Neuroscience - November 3, 2016 Category: Neuroscience Source Type: research

Noninvasive assessment of the intracranial pressure in non-traumatic intracranial hemorrhage
This study provides further evidence that in patients with intracranial hemorrhage and SAH, the presence of ONSD greater than a threshold of 5.5mm is significantly predictive of invasively measured elevated ICP. The prediction of raised ICP can be further refined by measuring ONSD at the point where the optic nerve and the ophthalmic artery cross, and by determining the ratio between the ONSD and ETD.
Source: Journal of Clinical Neuroscience - September 5, 2016 Category: Neuroscience Source Type: research

Mechanical thrombectomy with the Solitaire AB stent for treatment of acute basilar artery occlusion: A single-center experience
Publication date: October 2016 Source:Journal of Clinical Neuroscience, Volume 32 Author(s): Shiwei Du, Gengsheng Mao, Dongmei Li, Ming Qiu, Qingbin Nie, Haibo Zhu, Yang Yang, Youping Zhang, Youxiang Li, Zhongxue Wu Basilar artery occlusion (BAO) remains one of the most devastating subtypes of ischemic stroke, and prognosis is poor if early recanalization is not achieved. The purpose of this study was to evaluate the safety and technical feasibility of mechanical thrombectomy with the Solitaire AB stent (Covidien, Irvine, CA, USA) for the treatment of acute BAO through a single-center experience. Twenty-one patients with ...
Source: Journal of Clinical Neuroscience - August 31, 2016 Category: Neuroscience Source Type: research

Methamphetamine-related brainstem haemorrhage
We report the case of an otherwise healthy 29-year-old woman who presented with a brainstem haemorrhage following intravenous methamphetamine use. Extensive investigation did not reveal an underlying pathology, and the development of symptoms was temporally related to methamphetamine injection. Although intracerebral haemorrhage secondary to methamphetamine use is well documented, this report describes a haemorrhage within the brainstem which is a rare location. While animal studies have demonstrated the potential of methamphetamines to produce brainstem haemorrhages, there has only been one previous report describing a ha...
Source: Journal of Clinical Neuroscience - August 31, 2016 Category: Neuroscience Source Type: research

Five-year experience of 101 adult patients with moyamoya disease at a single institution in Eastern China
Publication date: Available online 6 August 2016 Source:Journal of Clinical Neuroscience Author(s): Jian-Hua Cheng, Qiang Ye, Zu-sen Ye, Ze-qun Li, An-ding Xu This retrospective study included 101 adult moyamoya disease (MMD) patients of whom 58 were females and 43 were males in Wenzhou, China. Clinical and diagnostic features, surgical treatment, follow-up information and outcomes constitute this review. The modified Rankin Scale (mRS) was used to determine the neurological functional outcome. The Kaplan–Meier method was used to estimate recurrent stroke and mortality risk based on drug treatment alone or in combinatio...
Source: Journal of Clinical Neuroscience - August 7, 2016 Category: Neuroscience Source Type: research

Acute stroke with major intracranial vessel occlusion: Characteristics of cardioembolism and atherosclerosis-related in situ stenosis/occlusion
Publication date: Available online 6 August 2016 Source:Journal of Clinical Neuroscience Author(s): Nobutaka Horie, Yohei Tateishi, Minoru Morikawa, Yoichi Morofuji, Kentaro Hayashi, Tsuyoshi Izumo, Akira Tsujino, Izumi Nagata, Takayuki Matsuo Acute ischemic stroke with major intracranial vessel occlusion is commonly due to cardioembolic or atherosclerosis-related in situ stenosis/occlusion, and immediate identification of these subtypes is important to establish the optimal treatment strategy. The aim of this study was to clarify the differences in clinical presentation, radiological findings, neurological temporal cours...
Source: Journal of Clinical Neuroscience - August 6, 2016 Category: Neuroscience Source Type: research

Increased risk for complications following diagnostic cerebral angiography in older patients: Trends from the Nationwide Inpatient Sample (1999–2009)
Publication date: Available online 16 July 2016 Source:Journal of Clinical Neuroscience Author(s): Omar Choudhri, Matthew Schoen, Aditya Mantha, Abdullah Feroze, Rohaid Ali, Michael T. Lawton, Huy M. Do The full utility of diagnostic cerebral angiography, an invasive cerebrovascular imaging technique, is currently debated. Our goal was to determine trends in diagnostic cerebral angiography utilization and associated complications from 1999 through 2009. The National Inpatient Sample (NIS) was used to identify patients who received primary cerebral angiography from 1999–2009 in the United States. We observed tren...
Source: Journal of Clinical Neuroscience - July 16, 2016 Category: Neuroscience Source Type: research

Transcranial magnetic stimulation (TMS) in stroke: Ready for clinical practice?
Publication date: Available online 6 July 2016 Source:Journal of Clinical Neuroscience Author(s): Marie-Claire Smith, Cathy M. Stinear The use of transcranial magnetic stimulation (TMS) in stroke research has increased dramatically over the last decade with two emerging and potentially useful functions identified. Firstly, the use of single pulse TMS as a tool for predicting recovery of motor function after stroke, and secondly, the use of repetitive TMS (rTMS) as a treatment adjunct aimed at modifying the excitability of the motor cortex in preparation for rehabilitation. This review discusses recent advances in the u...
Source: Journal of Clinical Neuroscience - July 6, 2016 Category: Neuroscience Source Type: research

Somatosensory evoked potentials in carotid artery stenting: Effectiveness in ascertaining cerebral ischemic events
Publication date: Available online 10 June 2016 Source:Journal of Clinical Neuroscience Author(s): Rupendra Bahadur Adhikari, Masaaki Takeda, Manish Kolakshyapati, Shigeyuki Sakamoto, Mizuki Morishige, Yoshihiro Kiura, Takahito Okazaki, Katsuhiro Shinagawa, Nobuhiko Ichinose, Satoshi Yamaguchi, Kaoru Kurisu Somatosensory evoked potentials (SSEP) have been used in various endovascular procedures and carotid endarterectomy, but to our knowledge no literature deals exclusively with the utility of SSEP in carotid artery stenting (CAS). The purpose of this study was to evaluate the efficacy of SSEP in detecting cer...
Source: Journal of Clinical Neuroscience - June 9, 2016 Category: Neuroscience Source Type: research

International benchmarking for acute thrombolytic therapy implementation in Australia and Japan
Publication date: July 2016 Source:Journal of Clinical Neuroscience, Volume 29 Author(s): Hiroyuki Kawano, Christopher Levi, Yuichiro Inatomi, Heather Pagram, Erin Kerr, Andrew Bivard, Neil Spratt, Ferdinand Miteff, Toshiro Yonehara, Yukio Ando, Mark Parsons Although a wide range of strategies have been established to improve intravenous tissue plasminogen activator (IV-tPA) treatment rates, international benchmarking has not been regularly used as a systems improvement tool. We compared acute stroke codes (ASC) between two hospitals in Australia and Japan to study the activation process and potentially improv...
Source: Journal of Clinical Neuroscience - May 29, 2016 Category: Neuroscience Source Type: research

Pituitary aspergillus infection
We report a case of Aspergillus infection involving the pituitary gland and sellar region discovered in a 74-year-old man. The patient had a history of hypertension, chronic renal disease, autoimmune hemolytic anemia and presented with right eye pain, headaches and worsening hemiparesis. Imaging studies revealed a right internal carotid artery occlusion and an acute right pontine stroke along with smaller infarcts in the right middle cerebral artery distribution. Clinically, the patient was thought to have vasculitis. An infectious etiology was not identified. He developed respiratory distress and died. At autopsy, necroti...
Source: Journal of Clinical Neuroscience - May 29, 2016 Category: Neuroscience Source Type: research

Malignant cerebral swelling following cranioplasty
Publication date: Available online 14 May 2016 Source:Journal of Clinical Neuroscience Author(s): S. Honeybul, O. Damodaran, C.R.P. Lind, G. Lee Over the past few years there have been a number of case reports and small cohort studies that have described so called “malignant” cerebral swelling following an uneventful cranioplasty procedure. The pathophysiology remains to be established however it has been suggested that it may be related to a combination of failure of autoregulation and the use of closed vacuum suction drainage. The current study presents three further patients who had had a decompressive hemicra...
Source: Journal of Clinical Neuroscience - May 13, 2016 Category: Neuroscience Source Type: research

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