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Specialty: Neurology
Source: Journal of Stroke and Cerebrovascular Diseases
Education: Study
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Total 3074 results found since Jan 2013.
Decanoic acid mitigates ischemia reperfusion injury by modulating neuroprotective, inflammatory and oxidative pathways in middle cerebral artery occlusion model of stroke in rats
This study evaluated the effect of decanoic acid administered before and after ischemia reperfusion injury on neurological damage and post stroke recovery in rats.
Source: Journal of Stroke and Cerebrovascular Diseases - June 3, 2023 Category: Neurology Authors: Himanshu Sharma, KH Reeta, Uma Sharma, Vaishali Suri Source Type: research
Temporal patterns and distribution of pyroptosis-related molecules and effects of human mesenchymal stem cells on pyroptosis following cerebral ischemia/reperfusion in rats
Pyroptosis is a new type of programmed cell death that has a strong proinflammatory effect. The present study investigated the dynamic changes of pyroptosis-related molecules and the effect of mesenchymal stem cells (MSCs) on pyroptosis following cerebral ischemia/reperfusion (I/R).
Source: Journal of Stroke and Cerebrovascular Diseases - May 31, 2023 Category: Neurology Authors: Kuang Pan, Qingxia Peng, Zejia Huang, Zhaofei Dong, Weijye Lin, Yidong Wang Source Type: research
An elderly case with late carotid stent thrombosis: possible role of antiphospholipid antibodies
The case study speculates that the antiphospholipid antibodies acquired during the follow-up period of carotid artery stenting may cause late stent thrombosis that is resistant to direct oral anticoagulants. A 73-year-old man was hospitalized with complaints of weakness in the right lower extremity. The patient had undergone carotid artery stenting for symptomatic stenosis of the left internal carotid artery 6 years prior and had received antiplatelet therapy with clopidogrel 75 mg/day. As the patient had developed atrial fibrillation without stent stenosis at the age of 70 years, anticoagulation therapy with rivaroxaban...
Source: Journal of Stroke and Cerebrovascular Diseases - May 26, 2023 Category: Neurology Authors: Shinji Kitsuki, Kenji Fukuda, Tomonaga Matsushita, Yoshihisa Fukushima, Tetsuro Ago, Takanari Kitazono Tags: Case Report Source Type: research
Sex and age effects on risk of non-traumatic subarachnoid hemorrhage: Retrospective cohort study of 124,234 cases using electronic health records
This study describes the antecedent characteristics of SAH patients, compares the risk of SAH between women and men, and explores if this changes with age.
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2023 Category: Neurology Authors: Charlotte H Harrison, Maxime Taquet, Paul J Harrison, Peter J Watkinson, Matthew J Rowland Source Type: research
Effect of intra-arterial thrombolysis following successful endovascular thrombectomy on functional outcomes in patients with large vessel occlusion acute ischemic stroke: A post-CHOICE meta-analysis
Endovascular thrombectomy (EVT) is the standard treatment of acute ischemic stroke (AIS) due to large vessel occlusion (LVO). Although> 70% of patients in the trials assessing EVT for AIS-LVO had successful recanalization, only a third ultimately achieved favorable outcomes. A “no-reflow” phenomenon due to distal microcirculation disruption might contribute to such suboptimal outcomes. Combining intra-arterial (IA) tissue plasminogen activator (tPA) and EVT to reduce the distal microthrombi burden was investigated in a few studies.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2023 Category: Neurology Authors: Mohamed Elfil, Sherief Ghozy, Ahmed Elmashad, Hazem S Ghaith, Mohammad Aladawi, Alis J. Dicpinigaitis, Ossama Yassin Mansour, Priyank Khandelwal, Kaiz Asif, May Nour, Gabor Toth, Fawaz Al-Mufti Source Type: research
Clinical application of 3DSlicer and Sina in minimally invasive puncture drainage of elderly patients with spontaneous intracerebral hemorrhage under local anesthesia
This study aimed to compare the treatment efficacy of MIPD conducted under local anesthesia using either 3DSlicer + Sina application or computer tomography (CT)–guided stereotactic localization of hematomas in elderly patients diagnosed with ICH.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2023 Category: Neurology Authors: Xiaolin Hou, Dingjun Li, Yuan Yao, Lin Zeng, Chengxun Li Source Type: research
How little is enough? The feasibility of conducting a dose-escalation study for exercise training in people with stroke
Is it feasible and safe to conduct an exercise dose-finding study in people with stroke? Is it possible to determine a minimal dose of exercise required to see clinically meaningful improvements in cardiorespiratory fitness?
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2023 Category: Neurology Authors: Margaret Galloway, Dianne L Marsden, Robin Callister, Kirk I Erickson, Michael Nilsson, Coralie English Source Type: research
Area-level and individual-level socio-economic differences in health-related quality of life trajectories: Results from a 10-year longitudinal stroke study
We examined area-level (aSES) and individual-level (iSES) socio-economic status on trajectories of HRQoL to 10 years following stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2023 Category: Neurology Authors: Yichao A Sun, Hoang Phan, Marie-Jeanne Buscot, Amanda G Thrift, Seana Gall Source Type: research
Association between dietary antioxidant capacity and atherosclerotic carotid stenosis in patients with ischemic stroke
The aim of this study was to evaluate the relationship between dietary total antioxidant capacity (DTAC) and atherosclerotic carotid stenosis in patients with ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2023 Category: Neurology Authors: Jizi Ma, Xuerong Jia, Yaqian Xia, Min Peng, Yantong Chen, Jingjing Cai, Xinfeng Liu, Gelin Xu Source Type: research
Stroke as a cause of death in patients with cancer: a SEER-based study
Death from stroke is linked to cancer due to its pathogenesis and side effects of treatment. Despite this, guidelines regarding identifying cancer patients at the highest risk of mortality from stroke are unclear.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2023 Category: Neurology Authors: Yousef Tarek Sonbol, Anas Elgenidy, Ahmed K. Awad, Ahmed O. Elmehrath, Hassan Kobeissi, Ahmed M. Afifi, Sherief Ghozy Source Type: research
Social and health determinants related to adverse short-term outcomes after a first-ever stroke in adults younger than 65 years
Stroke-related mortality and disability-adjusted life years in adults younger than 65 have increased over the last decade. However, geographical differences in distributing these outcomes could reflect dissimilarity in determinants. Therefore, this cross-sectional study of secondary data from Chilean hospitals aims to analyze the association of sociodemographic and clinical factors with in-hospital case-fatality risk or acquired neurologic deficits (adverse outcomes) in inpatients aged 18 to 64 who experienced their first-ever stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2023 Category: Neurology Authors: Mauricio Lopez-Espejo, Rodrigo Poblete, Gabriel Bastias Source Type: research
Thrombectomy in ischemic stroke patients with alberta stroke program early computed tomography score 4-5 and 0-3: Factors associated with favorable outcome
Recently published results of the ANGEL-ASPECT and SELECT2 trials suggest that stroke patients presenting with low Alberta Stroke Program Early Computed Tomography Score (ASPECTS) benefit from mechanical thrombectomy. Purpose of this retrospective study was to identify factors that are associated with a favorable outcome in patients with low ASPECTS of 4-5 and 0-3 undergoing mechanical thrombectomy.
Source: Journal of Stroke and Cerebrovascular Diseases - May 6, 2023 Category: Neurology Authors: Ludger Feyen, Helge Kniep, Christian Blockhaus, Martin Weinzierl, Marcus Katoh, Patrick Haage, Stefan Rohde, Nico M ünnich Source Type: research
Intra-arterial thrombolysis as adjunct to mechanical thrombectomy in acute ischemic stroke patients in the United States: A case control analysis
Although observational studies have reported favorable clinical outcomes associated with intra-arterial thrombolysis as adjunct to mechanical thrombectomy, the cost and length of hospitalization associated with this intervention has not been studied.
Source: Journal of Stroke and Cerebrovascular Diseases - May 5, 2023 Category: Neurology Authors: Chun Shing Kwok, Navpreet K. Bains, Daniel E. Ford, Camilo R. Gomez, Daniel F. Hanley, Ameer E. Hassan, Thanh N. Nguyen, Farhan Siddiq, Alejandro M. Spiotta, Syed F. Zaidi, Adnan I. Qureshi Source Type: research
Mortality Following Mechanical Thrombectomy for Ischemic Stroke in Patients with COVID-19
Multiple prior studies have shown a relationship between COVID-19 and strokes; further, COVID-19 has been shown to influence both time-to-thrombectomy and overall thrombectomy rates. Using large-scale, recently released national data, we assessed the association between COVID-19 diagnosis and patient outcomes following mechanical thrombectomy.
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2023 Category: Neurology Authors: Jonathan Dallas, Talia A. Wenger, Kristie Q. Liu, Li Ding, Benjamin S. Hopkins, Frank J. Attenello, William J. Mack Source Type: research
Impact of socioeconomics and race on clinical follow-up and trial enrollment and adherence in cerebral cavernous malformation
Cerebral cavernous malformation (CCM) affects more than a million Americans but advanced care for symptomatic lesions and access to research studies is largely limited to referral academic centers
Source: Journal of Stroke and Cerebrovascular Diseases - May 3, 2023 Category: Neurology Authors: Stephanie Hage, Matthew Hagan, Dehua Bi, Agnieszka Stadnik, Justine Lee, Sharbel Romanos, Abhinav Srinath, Robert Shenkar, Cornelia Lee, Peleg M. Horowitz, Romuald Girard, Issam A. Awad Source Type: research
