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Specialty: Neurology
Source: Stroke
Education: Study

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Total 1821 results found since Jan 2013.

Association of Progression of Carotid Artery Wall Volume and Recurrent Transient Ischemic Attack or Stroke Clinical Sciences
Conclusions—The annual progression of carotid wall volume is independently associated with recurrent ischemic cerebrovascular events, and this measurement has added value for intraplaque hemorrhage and fibrous cap rupture in predicting future events.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Mingming Lu, Peng Peng, Yuanyuan Cui, Huiyu Qiao, Dongye Li, Jianming Cai, Xihai Zhao Tags: Clinical Studies, Magnetic Resonance Imaging (MRI), Atherosclerosis Original Contributions Source Type: research

Oxidative Stress Biomarkers of Brain Damage Clinical Sciences
Conclusions—Elevated hyperacute plasma F2-isoP concentrations independently predict the occurrence of IG and IG volume in patients with acute ischemic stroke. If validated in future studies, measuring plasma F2-isoP might be helpful in the acute setting to stratify patients with acute ischemic stroke for relative severity of ischemic injury and expected progression.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Svetlana Lorenzano, Natalia S. Rost, Muhib Khan, Hua Li, Fabricio O. Lima, Matthew B. Maas, Rebecca E. Green, Tijy K. Thankachan, Allison J. Dipietro, Ken Arai, Angel T. Som, Loc-Duyen D. Pham, Ona Wu, Gordon J. Harris, Eng H. Lo, Jeffrey B. Blumberg, Pau Tags: Ischemic Stroke Original Contributions Source Type: research

Predictors of Thrombolysis Administration in Mild Stroke Clinical Sciences
Conclusions—Mild acutely presenting stroke patients are more likely to receive thrombolysis if they are young, white, or Hispanic and arrive early to the hospital with more severe neurological presentation. Identification of predictors of thrombolysis is important in design of future studies to assess the use of thrombolysis for mild stroke.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Negar Asdaghi, Kefeng Wang, Maria A. Ciliberti-Vargas, Carolina Marinovic Gutierrez, Sebastian Koch, Hannah Gardener, Chuanhui Dong, David Z. Rose, Enid J. Garcia, W. Scott Burgin, Juan Carlos Zevallos, Tatjana Rundek, Ralph L. Sacco, Jose G. Romano Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Microvasospasms After Experimental Subarachnoid Hemorrhage Do Not Depend on Endothelin A Receptors Basic Sciences
Conclusions—Our results indicate that ETA receptors, which mediate large artery spasms after SAH, do not seem to play a role in the development of microarterial spasms, suggesting that posthemorrhagic spasms are mediated by distinct mechanisms in large and small cerebral vessels. Given that cerebral microvessel dysfunction is a key factor for outcome after SAH, further research into the mechanisms that underlie posthemorrhagic microvasospasms is urgently needed.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Hanhan Liu, Ari Dienel, Karsten Scholler, Susanne M. Schwarzmaier, Kathrin Nehrkorn, Nikolaus Plesnila, Nicole A. Terpolilli Tags: Basic Science Research, Mechanisms, Pathophysiology, Translational Studies, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Vagus Nerve Stimulation Enhances Stable Plasticity and Generalization of Stroke Recovery Basic Sciences
Conclusions—This study provides the first evidence that VNS paired with rehabilitative training after stroke (1) doubles long-lasting recovery on a complex task involving forelimb supination, (2) doubles recovery on a simple motor task that was not paired with VNS, and (3) enhances structural plasticity in motor networks.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Eric C. Meyers, Bleyda R. Solorzano, Justin James, Patrick D. Ganzer, Elaine S. Lai, Robert L. Rennaker II, Michael P. Kilgard, Seth A. Hays Tags: Animal Models of Human Disease, Rehabilitation, Ischemic Stroke Original Contributions Source Type: research

Reduced Intravoxel Incoherent Motion Microvascular Perfusion Predicts Delayed Cerebral Ischemia and Vasospasm After Aneurysm Rupture Brief Report
Conclusions—Decreased IVIM perfusion fraction f and blood flow–related parameter fD* correlate with DCI and proximal artery vasospasm development after cerebral aneurysm rupture.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Jeremy J. Heit, Max Wintermark, Blake W. Martin, Guangming Zhu, Michael P. Marks, Greg Zaharchuk, Robert L. Dodd, Huy M. Do, Gary K. Steinberg, Maarten G. Lansberg, Gregory W. Albers, Christian Federau Tags: Magnetic Resonance Imaging (MRI), Cerebral Aneurysm, Intracranial Hemorrhage, Aneurysm Brief Reports Source Type: research

Thrombus Neutrophil Extracellular Traps Content Impair tPA-Induced Thrombolysis in Acute Ischemic Stroke Brief Report
Conclusions—This study suggests that thrombus NETs content may be responsible for reperfusion resistance, including mechanical or pharmacological approaches with intravenous tPA, irrespectively of their etiology. The efficacy of a strategy involving an administration of DNAse 1 in addition to tPA should be explored in the setting of AIS.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT02907736.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Celina Ducroux, Lucas Di Meglio, Stephane Loyau, Sandrine Delbosc, William Boisseau, Catherine Deschildre, Malek Ben Maacha, Raphael Blanc, Hocine Redjem, Gabriele Ciccio, Stanislas Smajda, Robert Fahed, Jean-Baptiste Michel, Michel Piotin, Laurence Salom Tags: Inflammation, Pathophysiology, Vascular Biology, Ischemic Stroke Brief Reports Source Type: research

Quality of Life Is Poorer for Patients With Stroke Who Require an Interpreter Brief Report
Background and Purpose—In multicultural Australia, some patients with stroke cannot fully understand, or speak, English. Language barriers may reduce quality of care and consequent outcomes after stroke, yet little has been reported empirically.Methods—An observational study of patients with stroke or transient ischemic attack (2010–2015) captured from 45 hospitals participating in the Australian Stroke Clinical Registry. The use of interpreters in hospitals, which is routinely documented, was used as a proxy for severe language barriers. Health-Related Quality of Life was assessed using the EuroQoL-5 dimension-3 lev...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Monique F. Kilkenny, Natasha A. Lannin, Craig S. Anderson, Helen M. Dewey, Joosup Kim, Karen Barclay-Moss, Chris Levi, Steven Faux, Kelvin Hill, Brenda Grabsch, Sandy Middleton, Amanda G. Thrift, Rohan Grimley, Geoffrey Donnan, Dominique A. Cadilhac Tags: Race and Ethnicity, Mortality/Survival, Quality and Outcomes, Ischemic Stroke, Transient Ischemic Attack (TIA) Brief Reports Source Type: research

Implications of Recent Clinical Trials and Hypertension Guidelines on Stroke and Future Cerebrovascular Research Special Reports
Source: Stroke - February 26, 2018 Category: Neurology Authors: Daniel T. Lackland, Robert M. Carey, Adriana B. Conforto, Clive Rosendorff, Paul K. Whelton, Philip B. Gorelick Tags: Clinical Studies, Translational Studies, Epidemiology, Hypertension, Cerebrovascular Disease/Stroke Special Report Source Type: research

Stroke Prevention in the Very Elderly Topical Review
Source: Stroke - February 26, 2018 Category: Neurology Authors: Richard I. Lindley Tags: Clinical Studies, Aging, High Blood Pressure, Meta Analysis, Cerebrovascular Disease/Stroke Topical Reviews Source Type: research

Burden of Dilated Perivascular Spaces, an Emerging Marker of Cerebral Small Vessel Disease, Is Highly Heritable Clinical Sciences
Conclusions—We provide evidence for important genetic contribution to dPVS burden in older community-dwelling people, some of which may be shared with WMHV. Differential heritability patterns for dPVS in white matter and basal ganglia suggest at least partly distinct underlying biological processes.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Marie–Gabrielle Duperron, Christophe Tzourio, Muralidharan Sargurupremraȷ, Bernard Mazoyer, Aicha Soumare, Sabrina Schilling, Philippe Amouyel, Ganesh Chauhan, Yi–Cheng Zhu, Stephanie Debette Tags: Aging, Epidemiology, Genetics, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Stroke Incidence and Outcomes in Northeastern Greece Clinical Sciences
Conclusions—This is the largest to date population-based study in Greece documenting one of the highest stroke incidences ever reported in South Europe, highlighting the need for efficient stroke prevention and treatment strategies in Northeastern Greece.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Georgios Tsivgoulis, Athanasia Patousi, Maria Pikilidou, Theodosis Birbilis, Aristeidis H. Katsanos, Michalis Mantatzis, Aristeidis Asimis, Nikolaos Papanas, Panagiotis Skendros, Aikaterini Terzoudi, Aikaterini Karamanli, Ioannis Kouroumichakis, Pantelis Tags: Epidemiology, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Carotid Intima-Media Thickness Is Associated With White Matter Hyperintensities Clinical Sciences
Conclusions—Larger cIMT was associated with greater burden of cerebral WM lesions independently of demographics and traditional vascular risk factors, particularly among elderly and Hispanic participants, who are at high risk for stroke and cognitive decline.
Source: Stroke - January 22, 2018 Category: Neurology Authors: David Della-Morte, Chuanhui Dong, Matthew S. Markert, Mitchell S.V. Elkind, Ralph L. Sacco, Clinton B. Wright, Tatjana Rundek Tags: Epidemiology, Race and Ethnicity, Ultrasound Original Contributions Source Type: research

Cerebrovascular Outcomes With Proton Pump Inhibitors and Thienopyridines Clinical Sciences
Background and Purpose—Pharmacokinetic and prior studies on thienopyridine and proton pump inhibitors (PPI) coadministration provide conflicting data for cardiovascular outcomes, whereas there is no established evidence on the association of concomitant use of PPI and thienopyridines with adverse cerebrovascular outcomes.Methods—We conducted a systematic review and meta-analysis of randomized controlled trials and cohort studies from inception to July 2017, reporting following outcomes among patients treated with thienopyridine and PPI versus thienopyridine alone (1) ischemic stroke, (2) combined ischemic or hemorrhagi...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Konark Malhotra, Aristeidis H. Katsanos, Mohammad Bilal, Muhammad Fawad Ishfaq, Nitin Goyal, Georgios Tsivgoulis Tags: Meta Analysis, Ischemic Stroke Original Contributions Source Type: research

Association Between Heart Rate and Subclinical Cerebrovascular Disease in the Elderly Clinical Sciences
Conclusions—In a predominantly elderly cohort, elevated nighttime HR was associated with WMHV, suggesting an independent role of HR in subclinical cerebrovascular disease.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Koki Nakanishi, Zhezhen Jin, Shunichi Homma, Mitchell S.V. Elkind, Tatjana Rundek, Seitetz C. Lee, Aylin Tugcu, Mitsuhiro Yoshita, Charles DeCarli, Clinton B. Wright, Ralph L. Sacco, Marco R. Di Tullio Tags: Risk Factors, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research