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Total 181 results found since Jan 2013.

Her work paved the way for blockbuster obesity drugs. Now, she ’s fighting for recognition
When Svetlana Mojsov heard the spring 2021 announcement, she was startled. The Canada Gairdner International Award, a prestigious biomedical research prize, would be bestowed on three scientists for work underpinning the diabetes and obesity drugs that have exploded in popularity in recent years. “I was really upset,” recalls Mojsov, a chemist at Rockefeller University. The Gairdner award marked the third time in 4 years that the same trio of scientists—Joel Habener at Massachusetts General Hospital (MGH), Daniel Drucker at the University of Toronto, and Jens Juul Holst at the University of Copenhagen—were hon...
Source: Science of Aging Knowledge Environment - September 8, 2023 Category: Geriatrics Source Type: research

What is the role of 'theory' in training GP trainers?
Educ Prim Care. 2023 Sep 6:1-5. doi: 10.1080/14739879.2023.2253539. Online ahead of print.ABSTRACTA recent evaluation paper of the London General Practitioner Trainer Course by Knight et al questions the importance of educational theory in preparing GPs to become trainers and asks 'how much educational theory do GP trainers need to know in order to train effectively?' This paper places the authors' question under consideration, arguing that before the relationship between the theory and practice of education can be considered, the nature of 'educational practice' needs examination. There then follows a discussion of the wo...
Source: Primary Care - September 6, 2023 Category: Primary Care Authors: Samantha Scallan Source Type: research

Molecular design of environment-friendly chlorophenol (CP) derivatives based on 3D-QSAR assisted with a comprehensive evaluation method combining bioaccumulation and degradation
This study can provide theoretical support for the development of environment-friendly technology for emerging pollutants.PMID:37347327 | DOI:10.1007/s11356-023-28322-1
Source: Environmental Science and Pollution Research International - June 22, 2023 Category: Environmental Health Authors: Shuhai Sun Zeyang Liu Qing Li Yu Li Source Type: research

Fight Aging! Newsletter, May 22nd 2023
Conclusions to be Drawn A High Fat Diet Accelerates Atherosclerosis Less Directly than One Might Suspect How to Construct Measures of Biological Age A Long-Term Comparison of Metformin in Diabetics with Non-Diabetic Controls In Search of Distinctive Features of the Gut Microbiome in Long-Lived Individuals Greater Fitness in Humans Implies a Younger Epigenome and Transcriptome Intestinal Barrier Dysfunction as a Feature of Aging in Many Species NAFLD as an Age-Related Condition Towards Sensory Hair Cell Regeneration in the Inner Ear Raised Levels of PLG...
Source: Fight Aging! - May 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Viral nervous necrosis resistance in gilthead sea bream (Sparus aurata) at the larval stage: heritability and accuracy of genomic prediction with different training and testing settings
CONCLUSIONS: The estimate of the heritability for VNN symptomatology indicates that it is feasible to implement selective breeding programs for increased resistance to VNN of sea bream larvae/juveniles. Exploiting genomic information offers the opportunity of developing prediction tools for VNN resistance, and genomic models can be trained on EBV using all data or phenotypes, with minimal differences in classification performance of the trait phenotype. In a long-term view, the weakening of the genomic ties between animals in the training and test sets leads to decreased genomic prediction accuracies, thus periodical updat...
Source: Genet Sel Evol - April 4, 2023 Category: Genetics & Stem Cells Authors: Sara Faggion Paolo Carnier Rafaella Franch Massimiliano Babbucci Francesco Pascoli Giulia Dalla Rovere Massimo Caggiano Herv é Chavanne Anna Toffan Luca Bargelloni Source Type: research

Fight Aging! Newsletter, April 3rd 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 2, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Brain areas activated during visual learning in the cichlid fish Pseudotropheus zebra
Brain Struct Funct. 2023 Mar 15. doi: 10.1007/s00429-023-02627-w. Online ahead of print.ABSTRACTThe neural correlates of most cognitive functions in fish are unknown. This project aimed to identify brain regions involved in visual learning in the cichlid fish Pseudotropheus zebra. The expression of the protein pS6 was measured in 19 brain areas and compared between groups of individuals subjected to four different behavioral contexts (control, avoidance, trained, and novelty groups). Control group individuals were sacrificed with minimal interactions. Fish in the avoidance group were chased with a net for an hour, after wh...
Source: Brain Structure and Function - March 15, 2023 Category: Neuroscience Authors: R Calvo M H Hofmann V Schluessel Source Type: research