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Total 838 results found since Jan 2013.
Risk and prognostic factors in perinatal hemorrhagic stroke
Conclusion: Our findings showed that PHS was much more common in preterm infants. Mucosal bleeding and multiple lobes involvement were more common in term infants. PHS has high morbidity and mortality rates. Small for gestational age and mucosal bleeding were more common in infants who are dead.
Source: Annals of Indian Academy of Neurology - April 28, 2021 Category: Neurology Authors: H ü seyin Ç aksen Fatma Tuba K ö seoglu Ahmet Sami G ü ven H ü seyin Altunhan Mehmet Sinan Iyisoy Saim A ç ikg ö zoglu Source Type: research
& #8216;More than just skin in the game & #8217;. DADA2 autoinflammatory syndrome and stroke in the young
Ashin Varghese, Joe Thomas, Boby Varkey MaramattomAnnals of Indian Academy of Neurology 2021 24(3):410-412
A 21-year-old man had a long-standing history of leg ulcers and hyperpigmention over the feet. Over a span of 8 months, he had an acute ischemic stroke followed by a basal ganglia hemorrhage. He was finally diagnosed with DADA2 syndrome after genetic sequencing. The implications of this new syndrome and its links to stroke in the young are presented in this article.
Source: Annals of Indian Academy of Neurology - July 17, 2021 Category: Neurology Authors: Ashin Varghese Joe Thomas Boby Varkey Maramattom Source Type: research
The Association Between Sleep and Health-Related Quality of Life in Stroke Survivors
The American Academy of Sleep Medicine recommends adults engage in a minimum of 7 hours of sleep per 24 hour interval to optimize health. Stroke recovery, with its foundations in neuroplasticity, is impacted by sleep. The purpose of this study was to examine stroke survivor data from the 2018 Behavioral Risk Factor Surveillance System (BRFSS), and to compare self-reported measures of physical health (PH) and mental health (MH) for those individuals who met sleep guidelines to those who did not.
Source: Archives of Physical Medicine and Rehabilitation - September 28, 2021 Category: Rehabilitation Authors: David Levine, Cindy Poole, Christine Hostetler, Kendall Jeter, Cara Kingrea, Kloe Kukta, Nancy Fell Tags: Research Poster 1709896 Source Type: research
Agonistic analog of growth hormone-releasing hormone promotes neurofunctional recovery and neural regeneration in ischemic stroke Neuroscience
Ischemic stroke can induce neurogenesis. However, most stroke-generated newborn neurons cannot survive. It has been shown that MR-409, a potent synthetic agonistic analog of growth hormone–releasing hormone (GHRH), can protect against some life-threatening pathological conditions by promoting cell proliferation and survival. The present study shows that long-term treatment with MR-409...
Source: Proceedings of the National Academy of Sciences - November 15, 2021 Category: Science Authors: Yueyang Liu, Jingyu Yang, Xiaohang Che, Jianhua Huang, Xianyang Zhang, Xiaoxiao Fu, Jialing Cai, Yang Yao, Haotian Zhang, Ruiping Cai, Xiaomin Su, Qian Xu, Fu Ren, Renzhi Cai, Andrew V. Schally, Ming-Sheng Zhou Tags: Neuroscience Biological Sciences Source Type: research
Acute ischemic stroke in children & #8211; should we thrombolyze ?
KP Vinayan, Vivek Nambiar, Vaishakh AnandAnnals of Indian Academy of Neurology 2022 25(1):21-25
Ischemic stroke is a major cause of acute neurological symptoms in children with significant long-term neurological sequelae. Unlike in the adult population, the clinical presentation of strokes in children may not be stereotyped. Hence, many other differential diagnostic possibilities might have to be considered in the emergency setting. Due to this heterogeneous presentation and the resultant clinical dilemma in the early detection, acute thrombolysis even now remains as a very rarely tried therapeutic option in children. Man...
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: KP Vinayan Vivek Nambiar Vaishakh Anand Source Type: research
A Review of the Current Literature and Updates on Embolic Stroke of Undetermined Source (ESUS)
AbstractPurpose of ReviewThe initial ESUS construct presumed that atrial fibrillation (AF) would be detected in a substantial percentage of patients, but subsequent studies have determined that the rate of AF detection is much lower than anticipated, thereby highlighting other potential causes of ESUS. To date, there is no clear consensus supporting PFO closure or anticoagulation in ESUS patients. In this review, we discuss the recent studies on potential causes of ESUS and related work-up as well as report the recent trials on the treatment of ESUS.Recent FindingsSome of the potential causes of ESUS are undetected AF, pat...
Source: Current Treatment Options in Neurology - August 6, 2022 Category: Neurology Source Type: research
Tenecteplase and alteplase for thrombolysis of acute ischemic stroke within 4.5 hours: An efficacy and safety study
Conclusions: This study showed a comparable efficacy and safety profile of alteplase and TNK in thrombolysis of AIS throughout the 4.5 hours window period. Moreover, the ease of administration and better pharmacodynamic properties favors tenecteplase.
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Nikita Dhar Mritunjai Kumar Ashutosh Tiwari Ishita Desai Govind Madhaw Niraj Kumar Source Type: research
Dual antiplatelet therapy for minor ischemic stroke and transient ischemic attack
This article highlights newer trial data and recognizes a significant change in therapeutic management for patients suffering a minor ischemic stroke and/or transient ischemic attack.
Source: Journal of the American Academy of Physician Assistants - November 24, 2022 Category: Primary Care Tags: Pharmacology Consult Source Type: research
Evaluation of vascular cognitive impairment using the ICMR-Neuro cognitive tool box (ICMR-NCTB) in a stroke cohort from India
Conclusion: The ICMR-NCTB is a valid neuropsychological toolbox that can be used for comprehensive cognitive assessment and diagnosis of VCI in India. In addition, the Indian version of MoCA is more adept as a screening instrument to detect VCI due to its high sensitivity. The ICMR-NCTB will aid in early detection and management of many patients, thereby reducing the burden of vascular MCI and dementia in India.
Source: Annals of Indian Academy of Neurology - December 3, 2022 Category: Neurology Authors: Subhash Kaul Sheetal Goyal Avanthi Paplikar Feba Varghese Suvarna Alladi Ramshekhar Menon Meenakshi Sharma RS Dhaliwal Amitabha Ghosh Jwala Narayanan Ashima Nehra Manjari Tripathi Source Type: research
Biosimilar tenecteplase versus alteplase in acute ischemic stroke: A real world study
Conclusion: This present study observed no difference in the efficacy and safety between biosimilar TNK and rTPA. Our findings are in concordance with published trials showing equivalence between the two molecules.
Source: Annals of Indian Academy of Neurology - January 25, 2023 Category: Neurology Authors: Ayush Mohan Snigdha Komakula Suhas Murali Pooja Anand Dyuti Shah VY Vishnu Awadh Kishor Pandit Ayush Agarwal Deepti Vibha Mamta Bhushan Singh MV Padma Srivastava Rohit Bhatia Source Type: research
World Stroke Academy revamped
Source: International Journal of Stroke - January 21, 2013 Category: Neurology Authors: Michael Brainin Tags: Editorial Source Type: research
A rare cause of perioperative stroke
Sapna Erat Sreedharan, P Gayatri, PN SylajaAnnals of Indian Academy of Neurology 2013 16(1):103-105Perioperative stroke can occur following 0.2-0.3% of general surgical and orthopedic procedures. We are reporting a patient who developed multiple strokes in the immediate postoperative period following total knee replacement, where etiological workup revealed multiple pulmonary arteriovenous fistulae (PAVF). The significance of PAVF with paradoxical embolism in perioperative settings has rarely been reported in the literature.
Source: Annals of Indian Academy of Neurology - February 25, 2013 Category: Neurology Authors: Sapna Erat SreedharanP GayatriPN Sylaja Source Type: research
Structural kinetics of the myosin power stroke Biochemistry
We have used transient kinetics, nanosecond time-resolved fluorescence resonance energy transfer (FRET), and kinetics simulations to resolve a structural transition in the Dictyostelium myosin II relay helix during the actin-activated power stroke. The relay helix plays a critical role in force generation in myosin, coupling biochemical changes in the ATPase...
Source: Proceedings of the National Academy of Sciences - April 30, 2013 Category: Science Authors: Muretta, J. M., Petersen, K. J., Thomas, D. D. Tags: Biological Sciences Source Type: research
New Guidelines on tPA in Stroke: Putting Out Fires With Gasoline?
When a joint panel representing the American College of Emergency Physicians (ACEP) and the American Academy of Neurology (AAN) issued guidelines on the use of recombinant tissue-type plasminogen activator (rt-PA, alteplase, or tPA) in patients receiving a diagnosis of ischemic stroke, proponents of this treatment may have heaved a sigh of relief.
Source: Annals of Emergency Medicine - June 29, 2013 Category: Emergency Medicine Authors: William B. Millard Tags: News and Perspective Source Type: research
Outcomes of neuropsychological interventions of stroke
Xiao-Di Xu, Hong-Yan Ren, Ravi Prakash, Vijayadas , Rajesh KumarAnnals of Indian Academy of Neurology 2013 16(3):319-328The reported prevalence of cognitive deficits within the first month of stroke ranges widely from 10% to 82%, depending primarily on the criteria used to define cognitive impairment and on the selected patient population. These cognitive defects progress toward impairment over a course of time if left untreated. Among the most common cognitive deficits are the attentional, the visuoperceptual, the memory and executive function deficits. As these impairments are being increasingly recognized ...
Source: Annals of Indian Academy of Neurology - August 26, 2013 Category: Neurology Authors: Xiao-Di XuHong-Yan RenRavi PrakashVijayadasRajesh Kumar Source Type: research
