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History of Pediatric Nephrology in T ürkiye
This article analyzes the foundation, institutiona-lization, and development of pediatric nephrology in Türkiye. Erich Frank is the pioneer and inspiration for Turkish nephrologists. He pioneered the training of a new generation of modern physicians, the first generation of Turkish nephrologists, and the establishment of the discipline of nephrology. Turkish pediatricians closely followed these developments and tried to improve their knowledge, making an effort to study abroad. These physicians established pediatric nephrology departments in their universities, trained young pediatric nephrologists, initiated pediatric he...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - July 27, 2023 Category: Transplant Surgery Authors: Ayfer G ür Güven Source Type: research

YouTube as a platform for knowledge and awareness of peritoneal dialysis: A content analysis
CONCLUSIONS: Universities and societies should upload videos to provide easy-to-understand information on PD. Also, the important benefits of PD, like the preservation of RKF, should be further highlighted in these videos. It may increase the PD penetrance by increasing patients' awareness.PMID:34369832 | DOI:10.1177/08968608211035947
Source: Peritoneal Dialysis International - August 9, 2021 Category: Urology & Nephrology Authors: Hasan Haci Yeter Omer Faruk Akcay Source Type: research

A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists
Conclusion and Future Directions G protein bias may either be affinity/potency-dominant or efficacy-dominant (Table 1). A potential concern is that, despite using the same cellular assays, variations in agonist potency were determined by different, or even the same labs, potentially due to differences in expression levels of the receptor and signaling proteins that occurred during cell passaging. For example the reported arrestin recruitment potency for U69,593 has been reported to be as low as 67.7 nM (Spetea et al., 2017) and as high as 410 nM (Dunn et al., 2018), similarly for U50,488 potency has ranged from 36 to 1000...
Source: Frontiers in Pharmacology - April 16, 2019 Category: Drugs & Pharmacology Source Type: research