Applying Improvement Science to Peritoneal Access-Why We Need to Understand What Works and What Does Not.
Authors: Wilkie M PMID: 31501289 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Laparoscopic Peritoneal Dialysis Catheter Placement with Chest Wall Exit Site for Neonate with Stoma.
This report describes the operative technique including omentectomy, placement of a percutaneous stitch between the catheter cuffs, and fibrin glue injection around the catheter. The patient had no catheter-related infections. Laparoscopic-assisted PD catheter placement with chest wall exit site is a safe alternative in patients with any type of abdominal stoma. PMID: 31501290 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

A Theory-Driven, Evidence-Based Approach to Implementing the ISPD Syllabus-Patients as Learners.
Authors: Maley MAL, Patel RS, Lafferty NT, Steiner GZ, Chow JSF, Johnson DW, Boudville NC PMID: 31501291 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Depression at Baseline Is an Independent Risk Factor for Cognitive Decline in Patients on Peritoneal Dialysis: A Multicenter Prospective Cohort Study.
Conclusion:Depression was a significant risk factor for worsening of CI in PD patients. PMID: 31501292 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal Ultrafiltration for Heart Failure: Lessons from a Randomized Controlled Trial.
We describe methods, trial activity, and lessons learned.The trial aimed to recruit 130 participants with severe diuretic-resistant HF (New York Heart Association [NYHA] 3/4) and chronic kidney disease (CKD) stage 3/4 on optimal medical treatment for ≥ 4 weeks from 6 UK centers. Participants were randomized to either continuation of conventional HF treatment or to additionally receiving PuF (1 overnight exchange using Icodextrin dialysate). Primary outcome was change in 6-minute walk test (6MWT) between baseline and 28 weeks (end of trial). Secondary outcomes were changes in patient reported quality of life as assessed ...
Source: Peritoneal Dialysis International - September 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Synchronous Laparoscopic Insertion of Peritoneal Dialysis Catheter and Cholecystectomy in Patients with End-Stage Renal Disease and Gallstones - Our Experience.
This article presents our experience with synchronous laparoscopic cholecystectomy and insertion of a PD catheter. PMID: 31501294 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Computer Simulations of Continuous Flow Peritoneal Dialysis Using the 3-Pore Model-a First Experience.
Authors: Öberg CM, Martuseviciene G PMID: 31501295 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Budget impact analysis of the change in peritoneal dialysis use rate in korea.
CONCLUSION: In all scenarios from the payer's perspective, sav-ings could be achieved through an increase in PD use. Selecting PD for ESRD patients without different expected clinical outcomes between HD and PD would be beneficial to the NHI budget. PMID: 31337696 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - July 26, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Randomized controlled trial on adjunctive lavage for severe peritonitis.
CONCLUSIONS: Adjunctive lavage did not improve the overall out-come, although it may be beneficial for the more severe peritonitis patients who have high CRP. PMID: 31337697 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - July 26, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Remote patient monitoring program in automated peritoneal dialysis: impact on hospitalizations.
CONCLUSIONS: The use of RPM in APD patients is associated with lower hospitalization rates and fewer hospitalization days; RPM could constitute a tool for improvement of APD therapy. PMID: 31337698 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - July 26, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Direct comparison of the thickness of the parietal peritoneum using peritoneal biopsy and ultrasonography of the abdominal wall in patients treated with peritoneal dialysis.
DIRECT COMPARISON OF THE THICKNESS OF THE PARIETAL PERITONEUM USING PERITONEAL BIOPSY AND ULTRASONOGRAPHY OF THE ABDOMINAL WALL IN PATIENTS TREATED WITH PERITONEAL DIALYSIS. Perit Dial Int. 2019 Jul 23;: Authors: Abrahams AC, Dendooven A, van der Veer JW, Wientjes R, Toorop RJ, Bleys RL, Hendrickx AP, van Leeuwen MS, de Lussanet QG, Verhaar MC, Stapper G, Nguyen TQ Abstract BACKGROUND: Long-term treatment with peritoneal dialysis (PD) results in peritoneal fibrosis. Peritoneal biopsies have been used to determine the severity of fibrosis. Ultrasonography (US) of the abdominal wall has been used to meas...
Source: Peritoneal Dialysis International - July 26, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Patient perspectives on renal replacement therapy modality choice: a multicenter questionnaire study on bioethical dimensions.
CONCLUSIONS: Our study demonstrates that PD patients showed more scrutiny of their situation as patients, especially their co-patients. Their treatment empowered them toward feeling more autonomous than HD patients. These new insights into patient perspectives on RRT choice might facilitate modality choice for nephrologists. PMID: 31337700 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - July 26, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Can Lower Dialysate Sodium Concentrations Contribute to Blood Pressure Control in Peritoneal Dialysis?
Authors: Wilkie M, Davies S PMID: 31296774 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - July 13, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Review of Antibiotic Dosing with Peritonitis in APD.
Authors: Mancini A, Piraino B Abstract Peritonitis is the leading cause of transfer from peritoneal dialysis (PD) to hemodialysis (HD). It is also the leading cause of hospitalization of PD patients. The usual treatment of peritonitis for automated PD (APD) patients consists of antibiotics given once daily in the long dwell. However, the once-daily antibiotic dosing recommendations are based primarily on studies with continuous ambulatory PD (CAPD) regimens. Published studies on antibiotic dosing in APD are very limited. We will review the scant literature on this topic. It is possible that extrapolating once-daily...
Source: Peritoneal Dialysis International - July 13, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Comparison of Cardiovascular Outcomes by Dialysis Modality: A Systematic Review and Meta-Analysis.
Authors: Lozier MR, Sanchez AM, Lee JJ, Tamariz LJ, Valle GA Abstract Debates exist regarding the merit of starting one dialysis modality over the other for improved cardiovascular outcomes. Five previously published prospective and retrospective cohort studies have reported inconsistent conclusions on this topic. The aim of this systematic review and meta-analysis is to evaluate the influence initiation of hemodialysis (HD) vs peritoneal dialysis (PD) may have on the relative risk (RR) of subsequent development of adverse cardiovascular events (ACVE) in patients with end-stage renal disease (ESRD). Of the 518 reco...
Source: Peritoneal Dialysis International - July 13, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Strategies to Prevent Peritonitis after Procedures: Our Opinions.
Authors: Chaudhry RI, Chopra T, Fissell R, Golper TA Abstract Peritoneal Dialysis (PD) patients are at increased risk of peritonitis following elective colonoscopy and other potentially invasive dental or gynecological procedures. The increased risk of iatrogenic peritonitis is attributed to procedure-related factors such as instrumentation, biopsies, tissue injury, and peri-procedural bacterial contamination. Also contributory are patient-related factors such as the effect of the immunocompromised status of end-stage renal disease and the presence of intraperitoneal dialysate on the disruption of natural host defe...
Source: Peritoneal Dialysis International - July 13, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Chromium: Rise and Shine in Peritoneal Dialysis Patients?
Authors: Filler G, McIntyre C Abstract Some trace elements are altered with chronic kidney disease. Selenium, zinc, and manganese tend to be wasted, and there is growing evidence that selenium deficiency is associated with mortality on dialysis. Other trace elements accumulate, such as chromium, cobalt, lead, molybdenum, and vanadium. The highest chromium levels are found in dialysis patients. The dialysis modality may further affect these levels, especially in hemodialysis patients, where even small contaminations in the dialysis feed water may lead to a concentration gradient that increases the concentration of c...
Source: Peritoneal Dialysis International - July 13, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

The Norm Bourke Box: A Patient-Led Initiative to Improve Care for Rural Patients Requiring Peritoneal Dialysis.
This article describes a patient-led initiative-the "Norm Bourke Box" (NBB) for patients requiring PD in rural New South Wales, Australia. The NBB provides necessary equipment including bathroom scales and a blood pressure machine, that are not supplied by the health service. For patients, this has enabled a "good start" to PD and has helped to alleviate the financial burden and stress of needing to source the equipment required for PD. This also gave patients and staff reassurance because patients could undertake training with the equipment that they would be using at home to support efficient and safe...
Source: Peritoneal Dialysis International - July 13, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Where There is No Peritoneal Dialysis Fluid: A Case Series from Malawi.
Authors: Khomba MM, Munthali CK, Mulenga C, Bjornstad EC PMID: 31296780 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - July 13, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Free water transport and its association with cardiovascular status in children on peritoneal dialysis.
The objective was to define a FWT value of clinical significance in children on PD, fixing its relationship to left ventricular mass index (LVMI) as a well-known outcome parameter. METHODS: MiniPET was performed with 3.86% glucose, 1-h long, to measure FWT in PD patients> 6 years old. An echocardiogram (ECG) was performed within 2 months of the MiniPET. Left ventricular hypertrophy was defined as LVMI ≥ 38.6 g/height2.7 (95th percentile). Receiver operating characteristic curve (ROC) analysis was used to determine the cut-off value of FWT searching the highest sensitivity and specificity to differentiate patients...
Source: Peritoneal Dialysis International - May 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Residual renal function and effect of low-sodium solution on blood pressure in peritoneal dialysis patients.
CONCLUSIONS: The reduction of BP with a sodium-reduced PDF seems to be more effective in patients with no or low RRF than in patients with residual capacity of renal sodium and fluid control. PMID: 31123069 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

A peritoneal dialysis access quality improvement initiative: a single-center experience.
CONCLUSION: Our PD catheter QI initiative involved tracking, outcome reporting, defining PD catheter dysfunction and PD access insertion pathway development, yielding important insights into opportunities for program improvement. Multicenter research initiatives are needed to further improve PD access dysfunction definitions and to establish the best benchmarks for these metrics. PMID: 31123070 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Changes in outcomes over time among incident peritoneal dialysis patients in southern china.
CHANGES IN OUTCOMES OVER TIME AMONG INCIDENT PERITONEAL DIALYSIS PATIENTS IN SOUTHERN CHINA. Perit Dial Int. 2019 May 23;: Authors: Peng Y, Ye H, Yi C, Wu M, Huang X, Xiao X, Yu XQ, Yang X Abstract BACKGROUND: The present study was to investigate the changes in outcomes of incident patients who started peritoneal dialysis (PD) between 2006 - 2010 and 2011 - 2015 in Southern China. METHODS: In this single-center cohort study, incident PD patients from January 1, 2006, to December 31, 2015, were enrolled. Collected data included baseline demographic, clinical, biochemical characteristics, and outcome...
Source: Peritoneal Dialysis International - May 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Repeat peritoneal dialysis exit-site infection: definition and outcomes.
CONCLUSION: We have developed the first definition for repeat ESI. Repeat ESI is clinically important and results in significant morbidity and mortality. Following repeat ESI, peritonitis rates are high and a significant number of patients switch dialysis modality. Studies are needed to determine whether interventions such as early catheter exchange would improve outcomes. PMID: 31123072 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Exit-site relocation: a novel, straightforward technique for exit-site infections.
CONCLUSION: The technique described herein is a safe, straightforward, and effective method for the treatment of chronic ESI while the patient remains on PD and avoids switching to hemodialysis. PMID: 31123073 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Pd assistance and relationship to co-existing geriatric syndromes in incident peritoneal dialysis therapy patients.
PD ASSISTANCE AND RELATIONSHIP TO CO-EXISTING GERIATRIC SYNDROMES IN INCIDENT PERITONEAL DIALYSIS THERAPY PATIENTS. Perit Dial Int. 2019 May 23;: Authors: Farragher J, Oliver M, Jain A, Flanagan S, Koyle K, Jassal SV Abstract BACKGROUND: Home dialysis therapies, including peritoneal dialysis (PD), are preferred treatment strategies, offering flexibility and improved wellbeing. However, patients with complex disease and comorbidity may require assistance with personal care and healthcare-related tasks. The study objective was to formally assess the type and frequency of PD assistance received by patient...
Source: Peritoneal Dialysis International - May 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Composite outcome improves feasibility of clinical trials in peritoneal dialysis.
CONCLUSION: Introduction of the composite outcome MAPE, covering relevant major adverse peritoneal events, may improve the feasibility of clinical trials to adequately test novel PD fluids. PMID: 31123075 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

The iron biology status of peritoneal dialysis patients may be a risk factor for development of infectious peritonitis.
CONCLUSIONS: Collectively, our study suggests transferrin and catecholamines within peritoneal dialysate may be indicators of the potential for bacterial growth in HPD and, as infection risk factors, represent possible future targets for therapeutic manipulation. PMID: 31123076 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Enabling Supported Self-Care.
Authors: Wilkie M PMID: 31088932 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 16, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal Protein Loss, Leakage or Clearance In Peritoneal Dialysis, Where Do We Stand?
Authors: Guedes AM Abstract Peritoneal protein loss (PPL) through peritoneal effluent has been a well-recognized detrimental result of peritoneal dialysis (PD) treatment since its inception. Investigation has focused mainly on PPL quantitative and qualitative determinations and evaluation of its prognostic value.A comprehensive review of the pathophysiology of PPL (3-pore model revisited), methods of quantification, dialysate protein composition, and impact on clinical outcomes is presented herein. The author summarizes a brief analysis of associated cardiovascular disease and nutritional consequences, exploring th...
Source: Peritoneal Dialysis International - May 16, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Spontaneous Fracture in Intramural and Intra-Abdominal Segments of Peritoneal Dialysis Catheters Presenting as Outflow Failure.
Authors: Wadhawan A, Saxena R Abstract We herewith report 2 unusual cases of spontaneous peritoneal dialysis (PD) catheter fracture in intramural and intra-abdominal segments, respectively, in PD patients with long vintage. There were no associated infections or mechanical trauma. The patients presented with PD catheter outflow failure. Both the patients had their catheter replaced and resumed PD without any further issues. Probable causes and comparison with the reported cases are discussed. PMID: 31088934 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 16, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Complete Resolution of Tumoral Calcinosis in a Patient on Peritoneal Dialysis with Cinacalcet.
Authors: Hayat A PMID: 31088935 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 16, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Effect of Peritoneal Dialysis Fluids on Activity of Teicoplanin Against Methicillin-Resistant Staphylococcus aureus Biofilm.
Authors: Tobudic S, Kern S, Kussmann M, Forstner C, Burgmann H PMID: 31088936 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 16, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Creating and maintaining optimal peritoneal dialysis access in the adult patient: 2019 update.
CREATING AND MAINTAINING OPTIMAL PERITONEAL DIALYSIS ACCESS IN THE ADULT PATIENT: 2019 UPDATE. Perit Dial Int. 2019 Apr 26;: Authors: Crabtree JH, Shrestha BM, Chow KM, Figueiredo AE, Povlsen JV, Wilkie M, Abdel-Aal AK, Cullis B, Goh BL, Briggs V, Brown EA, Dor FJ PMID: 31028108 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - April 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Prophylactic antibiotic reduces the risk of peritonitis after invasive gynecologic procedures.
CONCLUSION: The use of prophylactic antibiotic treatment considerably reduced the risk of peritonitis after invasive gynecologic procedures. PMID: 31028109 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - April 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Serum chromium levels are higher in peritoneal dialysis than in hemodialysis patients.
SERUM CHROMIUM LEVELS ARE HIGHER IN PERITONEAL DIALYSIS THAN IN HEMODIALYSIS PATIENTS. Perit Dial Int. 2019 Apr 26;: Authors: Feldman L, Beberashvili I, Abu Hamad R, Yakov-Hai I, Abramov E, Wasser W, Gorelik O, Rosenberg R, Efrati S Abstract BACKGROUND: An elevation in serum chromium levels in individuals treated with renal replacement therapy has been previously described, but chromium levels have not been systematically studied in patients treated with different dialysis modalities. The aim of this study was to compare serum chromium levels in patients treated with chronic peritoneal dialysis (PD) an...
Source: Peritoneal Dialysis International - April 29, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal Dialysis for People with Functional Impairment-What About Carer Support?
Authors: Wilkie M PMID: 30858283 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - March 14, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Exserohilum Peritonitis in Peritoneal Dialysis in Northern China: A Case Report.
Authors: Liu Y, Gong W, Yu Y, Jiang L Abstract Fungal peritonitis is a catastrophic complication of peritoneal dialysis (PD) and often requires termination of PD. It is usually caused by Candida species. Here we report a rare case of Exserohilum peritonitis. The patient was successfully treated with catheter removal and anti-fungal therapy. PMID: 30858284 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - March 14, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Evaluating Burden and Quality of Life among Caregivers of Patients Receiving Peritoneal Dialysis.
Authors: Kang A, Yu Z, Foo M, Chan CM, Griva K Abstract Peritoneal dialysis (PD) is advocated as treatment of choice for most end-stage renal disease (ESRD) patients, including elderly and frail patients. It typically requires caregiver involvement to support care at home. The purpose of this study was to examine changes in burden and quality of life (QOL) in caregivers of prevalent PD patients over 12 months. Data were collected in 44 caregivers of PD patients (mean age 38.4 ± 6.3 years; 60% female) in Singapore at baseline and 12 months. Measures included demographics, the Lay Care-Giving for Adults Receiv...
Source: Peritoneal Dialysis International - March 14, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Predictors of Quality of Life among Peritoneal Dialysis Patients with End-Stage Renal Disease in Kuwait.
Authors: Ibrahimou B, Albatineh AN Abstract Quality of life (QOL) is an important indicator of quality of healthcare. Measuring QOL and its correlates for peritoneal dialysis (PD) patients is important for public health policy, intervention, and clinical decision-making. Data from 62 patients treated at 6 dialysis centers were collected using short form (SF)-36. Multiple linear regression was used to assess the relationship between QOL and several covariates. Results indicated most patients were ≥ 60 years old (51.6%), retired (40.3%), diagnosed with end-stage renal disease (ESRD)> 1 year (82.3%), with diabet...
Source: Peritoneal Dialysis International - March 14, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Vancomycin Removal During High-Volume Peritoneal Dialysis in Acute Kidney Injury Patients.
Authors: Ponce D, Zamoner W, Freitas FM, Balbi A, Awdishu L Abstract Studies on vancomycin pharmacokinetics in acute kidney injury (AKI) patients on high-volume peritoneal dialysis (HVPD) are lacking. We studied the pharmacokinetics of intravenous (IV) vancomycin in AKI patients treated by HVPD who received a prescribed single IV dose of vancomycin (15 - 20 mg/kg total body weight) to determine the extent of vancomycin removal and to establish vancomycin dosing guidelines for the empirical treatment of AKI patients receiving HVPD. The application of 18 mg/kg vancomycin every 48 - 72 hours in AKI patients undergoing...
Source: Peritoneal Dialysis International - March 14, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Extended Experience in the Use of Antibiotic Lock for Eradication of Biofilm Bacteria on Tenckhoff Catheter.
Authors: Wong SS, Lau WY, Chan PK, Wan CK, Cheng YL Abstract Whilst antibiotic lock is effective to eradicate biofilm bacteria on hemodialysis catheters, this adjunctive method has scarcely been tested in peritoneal dialysis (PD) patients. After our previous successful experience of its use to salvage two Tenckhoff catheters, we encountered another patient with problematic biofilm-associated PD peritonitis who strongly refused catheter removal. As a result, antibiotic lock was given once daily, initially, with continuation of the usual PD schedule. However, relapsing peritonitis could not be prevented until we admi...
Source: Peritoneal Dialysis International - March 14, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Performance of Gram Stains and 3 Culture Methods in the Analysis of Peritoneal Dialysis Fluid.
We examined a laboratory cohort (samples sent to the laboratory for any reason; n = 251) and a clinical cohort (samples sent from patients felt clinically to have peritonitis; n = 264). Culture positivity rates were higher in the clinical cohort (39.4%) than the laboratory cohort (21.5%), with no difference in the distribution of organisms between the cohorts; cell counts were significantly higher in culture-positive samples in both cohorts.Rates of positivity in the laboratory and clinical cohorts, respectively, were as follows: Gram stains 1.9% and 7.7%; direct plate culture 13% and 30.8% and "bedside" inoculat...
Source: Peritoneal Dialysis International - March 14, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Safety of Intravenous Iron - Cosmofer and Monofer Therapy in Peritoneal Dialysis and Non-Dialysis-Dependent Chronic Kidney Disease Patients.
Authors: Sivakumar C, Jubb VM, Lamplugh A, Bhandari S Abstract Safety of parenteral iron therapy is critical and has been demonstrated in several studies, but concerns persist on safety. We performed a retrospective single-center study investigating the safety and efficacy of parenteral iron administration using 2 iron preparations-Monofer and Cosmofer (Pharmacosmos A/S, Holbaek, Denmark)-in patients with chronic kidney disease (CKD), on peritoneal dialysis (PD) and non-dialysis. A database of CKD patients receiving intravenous (IV) iron was analyzed. Side effects were recorded during infusion, post-infusion, and a...
Source: Peritoneal Dialysis International - March 14, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Constipation in peritoneal dialysis patients.
CONSTIPATION IN PERITONEAL DIALYSIS PATIENTS. Perit Dial Int. 2019 Mar 09;: Authors: Kosmadakis G, Albaret J, Da Costa Correia E, Somda F, Aguilera D Abstract Constipation in peritoneal dialysis (PD) is an infrequent but potentially serious condition affecting the mechanical properties of dialysis techniques and predisposing to bacterial intestinal translocation and eventual enteric peritonitis. Despite the importance of the problem, published literature is scarce, consisting mostly of uncontrolled single-center trials. This inconsistency may be attributed to the large number of clinical, radiological,...
Source: Peritoneal Dialysis International - March 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Icodextrin is associated with a lower mortality rate in peritoneal dialysis patients.
CONCLUSIONS: After adjustments for immortal time biases, ICO users were significantly associated with approximately 20% reduction in mortality, especially among early users. PMID: 30852520 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - March 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Simultaneous removal and reinsertion of the pd catheter in relapsing peritonitis.
CONCLUSION: Simultaneous catheter removal and replacement for peritonitis appears to be an effective procedure for maintaining patients on PD. PMID: 30852521 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - March 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

End-stage renal disease patients with low serum albumin: is peritoneal dialysis an option?
END-STAGE RENAL DISEASE PATIENTS WITH LOW SERUM ALBUMIN: IS PERITONEAL DIALYSIS AN OPTION? Perit Dial Int. 2019 Mar 09;: Authors: Singh T, Astor BC, Waheed S Abstract INTRODUCTION: Low serum albumin is associated with high mortality in patients with end-stage renal disease (ESRD) on chronic dialysis. Clinicians are reluctant to offer peritoneal dialysis (PD) as an option for dialysis for patients with low serum albumin due to concerns of loss of albumin with PD, but evidence supporting differences in outcomes is limited. We evaluated mortality based on dialysis modality in patients with very low serum albumin (
Source: Peritoneal Dialysis International - March 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

The association of cognitive impairment with peritoneal dialysis-related peritonitis.
THE ASSOCIATION OF COGNITIVE IMPAIRMENT WITH PERITONEAL DIALYSIS-RELATED PERITONITIS. Perit Dial Int. 2019 Mar 09;: Authors: Liao JL, Zhang YH, Xiong ZB, Hao L, Liu GL, Ren YP, Wang Q, Duan LP, Zheng ZX, Xiong Z, Dong J Abstract BACKGROUND: Research on the association between cognitive impairment (CI) and peritoneal dialysis (PD)-related peritonitis is limited. Therefore, we investigated whether CI contributed to the risk of PD-related peritonitis. METHODS: This prospective cohort study enrolled 458 patients from 5 PD centers between 1 March 2013, and 30 November 2013, and continued until 31 May 20...
Source: Peritoneal Dialysis International - March 11, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal dialysis cuff-shaving-a salvage therapy for refractory exit-site infections.
CONCLUSION: Cuff-shaving is a feasible rescue therapy to treat refractory exit-site infections. In our experience, it allowed resolution of infections in a significant proportion of cases, except for fungal agents, and therefore extended catheter survival time, besides being associated with a small rate of complications. PMID: 30846605 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - March 10, 2019 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research