Ecological momentary assessment to explore fatigue, mood and physical activity levels in people receiving peritoneal dialysis: A study protocol.
This study will be the first to explore the real-time relationships between fatigue, mood and physical activity in people with ESKD receiving peritoneal dialysis. Understanding the fluctuations people experience and the relationships between mood and physical activity and fatigue will inform clinical management and well-being intervention development. PMID: 33567965 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - February 13, 2021 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

ISPD recommendations for the evaluation of peritoneal membrane dysfunction in adults: Classification, measurement, interpretation and rationale for intervention.
Authors: Morelle J, Stachowska-Pietka J, Öberg C, Gadola L, La Milia V, Yu Z, Lambie M, Mehrotra R, de Arteaga J, Davies S Abstract GUIDELINE 1: A pathophysiological taxonomy: A pathophysiological classification of membrane dysfunction, which provides mechanistic links to functional characteristics, should be used when prescribing individualized dialysis or when planning modality transfer (e.g. to automated peritoneal dialysis (PD) or haemodialysis) in the context of shared and informed decision-making with the person on PD, taking individual circumstances and treatment goals into account. (practice point). ...
Source: Peritoneal Dialysis International - February 12, 2021 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Pharmacokinetics of culture-directed antibiotics for the treatment of peritonitis in automated peritoneal dialysis: A systematic narrative review.
The objectives of this study were to provide a summary of the pharmacokinetic data of some intraperitoneal (IP) antibiotics that could be used for both empirical and culture-directed therapy, as per the ISPD recommendations, and examine factors to consider when using IP antibiotics for the management of automated peritoneal dialysis (APD)-associated peritonitis. A literature search of PubMed, EMBASE, Scopus, MEDLINE and Google Scholar for articles published between 1998 and 2020 was conducted. To be eligible, articles had to describe the use of antibiotics via the IP route in adult patients ≥18 years old on APD in the c...
Source: Peritoneal Dialysis International - February 10, 2021 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

An inhibitor of Kr ├╝ppel-like factor 5 suppresses peritoneal fibrosis in mice.
CONCLUSIONS: These results indicate the involvement of KLF5 in the progression of experimental peritoneal fibrosis and suggest that Am80 may be potentially useful for the prevention of peritoneal fibrosis through inhibition of KLF5 expression. PMID: 33522431 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - February 3, 2021 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

ISPD guidelines for peritoneal dialysis in acute kidney injury: 2020 Update (paediatrics).
Authors: Nourse P, Cullis B, Finkelstein F, Numanoglu A, Warady B, Antwi S, McCulloch M Abstract SUMMARY OF RECOMMENDATIONS: 1.1 Peritoneal dialysis is a suitable renal replacement therapy modality for treatment of acute kidney injury in children. (1C)2. Access and fluid delivery for acute PD in children.2.1 We recommend a Tenckhoff catheter inserted by a surgeon in the operating theatre as the optimal choice for PD access. (1B) (optimal)2.2 Insertion of a PD catheter with an insertion kit and using Seldinger technique is an acceptable alternative. (1C) (optimal)2.3 Interventional radiological p...
Source: Peritoneal Dialysis International - February 3, 2021 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Unexpected sequelae of the COVID-19 pandemic: A strange case of myoclonus in the Tasmanian winter.
We present a case report of the unusual neurological complication he developed. PMID: 33499779 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - January 28, 2021 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal dialysis and Peritoneal Dialysis International: What's old is new again.
Authors: Perl J PMID: 33499780 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - January 28, 2021 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Omental wrap: Radiographic diagnosis confirmed surgically - Report of two cases in Grenada.
We report two cases of peritoneal dialysis (PD) catheter outflow obstruction from our developing PD program in Grenada, in which contrast studies accurately diagnosed omental wrap, allowing for prompt surgical correction. In both cases, the contrast study indicated the presence of omental wrapping, confirmed at time of surgical correction. Radiographic features of omental wrap are distinctive, which allows for reliable differentiation from other causes of obstruction. Radiographic contrast study reliably diagnoses the cause of peritoneal catheter obstruction, permitting prompt diagnosis and treatment. This is vital for reg...
Source: Peritoneal Dialysis International - January 8, 2021 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Case series of acute peritoneal dialysis in the prone position for acute kidney injury during the Covid-19 pandemic: Prone to complications?
We describe our experience in delivering acute PD during the surge in Covid-19 acute kidney injury (AKI) in the subset of patients requiring prone positioning. All seven patients included in this report were admitted to the intensive care unit with SARS-CoV-2 infection leading to ARDS, AKI and multisystem organ failure. All required renal replacement therapy, and prone positioning to improve ventilation/perfusion mismatch. All seven were able to continue PD despite prone positioning without any detrimental effects on respiratory mechanics or the need to switch to a different modality. Fluid leakage was noted in 71% of pati...
Source: Peritoneal Dialysis International - January 8, 2021 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Technique failure in remote patient monitoring program in patients undergoing automated peritoneal dialysis: A retrospective cohort study.
CONCLUSIONS: The use of an RPM program in APD patients may be associated with a lower technique failure rate. More extensive and interventional studies are needed to confirm its potential benefits and to measure other patient-centered outcomes. PMID: 33380265 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - January 1, 2021 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

How do patients and their family members experience the transition from peritoneal dialysis to incentre haemodialysis? A multisite qualitative study in England and Australia.
CONCLUSION: Although each transition is unique to the individual and their circumstances, kidney care services could optimise the process by recognising these patient-led themes and developing strategies that engage with them. Kidney care services should consider ways to keep patients aware of potential future treatment options and present them objectively. There is potential value in integrating expert support before and during treatment transitions to identify and address patient and family concerns. PMID: 33331224 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - December 18, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

ISPD guidelines for peritoneal dialysis in acute kidney injury: 2020 update (adults).
Authors: Cullis B, Al-Hwiesh A, Kilonzo K, McCulloch M, Niang A, Nourse P, Parapiboon W, Ponce D, Finkelstein FO Abstract SUMMARY STATEMENTS: (1) Peritoneal dialysis (PD) should be considered a suitable modality for treatment of acute kidney injury (AKI) in all settings (1B). GUIDELINE 2: ACCESS AND FLUID DELIVERY FOR ACUTE PD IN ADULTS: (2.1) Flexible peritoneal catheters should be used where resources and expertise exist (1B) (optimal).(2.2) Rigid catheters and improvised catheters using nasogastric tubes and other cavity drainage catheters may be used in resource-poor environments where they m...
Source: Peritoneal Dialysis International - December 5, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal dialysis in critically ill children in resource-limited setting: A prospective cohort study.
Authors: Choudhary P, Kumar V, Saha A, Thakur A Abstract BACKGROUND: Peritoneal dialysis (PD) is easily available and simple lifesaving procedure in children with renal impairment. There is paucity of reports on efficacy of PD in critically ill children in presence of shock and those requiring mechanical ventilation. METHODS: In this prospective observational study, efficacy and outcome of PD were evaluated in 50 critically ill children aged 1 month to 14 years admitted in pediatric intensive care unit of a tertiary care teaching hospital in India. RESULTS: Indication of PD was acute kidney injury (AKI) in ...
Source: Peritoneal Dialysis International - December 5, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Four steps to standardize reporting of peritoneal dialysis technique failure: A proposed approach.
CONCLUSIONS: The approach to reporting technique failure has an important impact on the observed results. We present a robust and transparent methodology to track technique failure over time and to compare performance between programs. PMID: 33272118 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - December 5, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Clinical characteristics associated with the properties of gut microbiota in peritoneal dialysis patients.
Authors: Jiang N, Zhang C, Feng H, Yuan J, Ding L, Fang W, Gu A, Huang J, Li N, Gu L, Ni Z, Mou S Abstract BACKGROUND: Gut microbiota alters in patients with end-stage renal disease, which contributes to inflammation, atherosclerosis, and results in increased incidence of cardiovascular diseases. The present study investigated the potential clinical factors, which influence the gut microbial structure and function in patients undergoing peritoneal dialysis (PD). METHODS: This is a cross-sectional study performed in 81 prevalent PD patients. Gut microbiota was assessed by high throughput sequencing of 16S riboso...
Source: Peritoneal Dialysis International - December 5, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal dialysis with a lower dosage versus conventional intermittent hemodialysis in acute kidney injury: A propensity-matched study.
CONCLUSION: Clinical outcomes, including risk of mortality and 90-day dialysis dependence among patients with AKI, appear to be comparable between lower dosage PD and IHD. PMID: 33249992 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - December 2, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

The Peritoneal Dialysis Telemedicine-assisted Platform Cohort (PDTAP) Study: Design and methods.
CONCLUSIONS: The PDTAP study aims to explore potential predictors and their effects on patient survival, technique survival, and infectious and noninfectious complications using a newly developed PD telemedicine system to collect multicenter, structured data in real-world practice. Substantial and transformable findings in relation to PD practices were expected. This study also developed a national-level infrastructure for further collaboration and ancillary investigation. PMID: 33249994 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - December 2, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Favorable effects of peritoneal dialysis in patients with refractory heart failure and overhydration.
CONCLUSIONS: PD showed to be a viable option for the treatment of patients with refractory HF leading to a better cardiac functional status and diminishing the number of hospital admissions. PMID: 33250003 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - December 2, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Intraperitoneal pressure: Stability over time and validation of Durand's measurement method.
In conclusion, Durand's method is precise enough to measure IPP in peritoneal dialysis. This parameter is not stable over long timescales, so it is necessary to use recent measurements. PMID: 33250004 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - December 2, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Utilization of CMS pre-ESRD Kidney Disease Education services and its associations with the home dialysis therapies.
CONCLUSIONS: Utilization of pre-ESRD KDE services is associated with significantly greater home dialysis utilization in the incident ESRD Medicare beneficiaries. The very low rates of utilization of these services suggest the need for focused systemic evaluations to identify and address the barriers and facilitators of this important patient-centered endeavor. PMID: 33258420 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - December 2, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Persistent colonization of exit site is associated with modality failure in peritoneal dialysis.
We report on a 1-year observational study of 23 patients who developed an ESI with one of these serious pathogens. After completing initial antibiotic treatment, swabs were taken every month for 3 months. Primary treatment cure occurred in 19/23 (83%). Colonization of ES after primary cure occurred in 8/19 (42%) patients. In the eight colonized patients, five had subsequent PD technique failure due to infections. By contrast, during an average follow-up period of 7.2 months, none of the 11 patients who were proven noncolonized developed PD technique failure from infections; HR (colonized vs. noncolonized) = 10.89, 95% CI 2.6-45.43, p
Source: Peritoneal Dialysis International - November 25, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

On the change of transport parameters with dwell time during peritoneal dialysis.
Authors: Waniewski J, Stachowska-Pietka J, Lindholm B Abstract The transitory change of fluid and solute transport parameters occurring during the initial phase of a peritoneal dialysis dwell is a well-documented phenomenon; however, its physiological interpretation is rather hypothetical and has been disputed. Two different explanations were proposed: (1) the prevailing view-supported by several experimental and clinical studies-is that a vasodilatory effect of dialysis fluid affects the capillary surface area available for dialysis, and (2) a recently presented alternative explanation is that the molecular radius...
Source: Peritoneal Dialysis International - November 18, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Digital health - The new reality. What does this mean for peritoneal dialysis?
Authors: Wilkie M PMID: 33176610 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - November 14, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal dialysis for acute kidney injury: Equations for dosing in pandemics, disasters, and beyond.
CONCLUSIONS: The equations are intended as a practical tool to estimate solute clearances and guide prescription of continuous PD. The estimated dialysate volume required for any dose target can be calculated from cycle duration or dwell volume. However, the exact target dose of PD is uncertain and should be adjusted according to the clinical circumstances and response to treatment. The equations presented in this article facilitate the adjustment of PD prescription toward the targeted solute clearance. PMID: 33174468 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - November 12, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Patient and caregiver perspectives on burnout in peritoneal dialysis.
CONCLUSIONS: For patients on PD and their caregivers, burnout was intensified by perceiving PD as an unrelenting, isolating responsibility that they had no choice but to endure, even if it held them back from doing other activities in life. More emphasis on developing strategies to adapt and build resilience could prevent or minimize burnout. PMID: 33174471 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - November 12, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal dialysis access outcomes reported in randomized controlled trials: A systematic review.
CONCLUSION: Variability exists in the definitions, reporting methods, choice of outcomes, and analysis of the PD access outcomes across RCTs. Operative-related outcomes remain underreported across RCTs. Outcomes relating to PD access flow restriction were the most common complications reported in the included RCTs but were reported heterogeneously with variability in reporting of the three key components of its definition including description and severity of the flow restriction, the need for intervention and etiology of flow restriction. In the future, defining PD access flow restriction should include all of these compo...
Source: Peritoneal Dialysis International - October 29, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Streptococcus salivarius peritonitis in an infant receiving chronic peritoneal dialysis.
We describe a 4-month-old male who developed S. salivarius peritonitis while receiving automated peritoneal dialysis and who was successfully treated with a 14-day course of intraperitoneal vancomycin. Subtyping episodes of S. viridans-related infection is essential for the identification of S. salivarius. PMID: 33084495 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 22, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Patients' and caregivers' expectations and experiences of remote monitoring for peritoneal dialysis: A qualitative interview study.
CONCLUSIONS: Remote monitoring may increase patient knowledge about their kidney disease and its treatment, encourage accountability to the clinical team, enhance partnerships with clinicians, and improve access to treatment and timely care. It is also important to ensure that remote monitoring does not replace face-to-face clinical contact with clinicians. PMID: 33084514 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 22, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Forty years of peritoneal dialysis Listeria peritonitis: Case and review.
We report a continuous cycling peritoneal dialysis (CCPD) patient who presented initially disseminated listeriosis with peritonitis. He was successfully treated with intraperitoneal and intravenous ampicillin but died unfortunately from a cardiorespiratory arrest due to food inhalation. It is the 20th case of such peritonitis mentioned among PD patients and the first reported in Belgium. This case illustrates the importance of a systematic approach to get quick diagnosis and effective antibiotic readjustment. Empiric therapy is not effective on Listeria which is naturally resistant to cephalosporins and poorly sensitive to...
Source: Peritoneal Dialysis International - October 9, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Corrigendum to A Randomized Controlled Trial to Determine the Appropriate Time to Initiate Peritoneal Dialysis after Insertion of Catheter (Timely PD Study).
Authors: PMID: 33025865 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 9, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Computerized adaptive technology for the assessment of HRQOL of PD and CKD patients.
This study was designed as a pilot study to see whether electronic patient-reported outcome measures using computer adaptive technology (CAT) could be successfully implemented in clinics caring for chronic kidney disease (CKD) and peritoneal dialysis (PD) patients. The results demonstrate the feasibility of using CAT on an iPad to assess the symptom burden and health-related quality of life of both PD and CKD patients. PMID: 33016231 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 6, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Rebuilding stronger - lessons from COVID-19.
Authors: Wilkie M PMID: 32998643 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 3, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Does SARS-CoV-2 reach peritoneal effluent?
Authors: Sadioglu RE, Aktar M, Gulten E, Eyupoglu S, Karahan ZC, Azap A, Sengul S, Ates K, Kutlay S PMID: 32998644 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 3, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Successfully treating three patients with acute kidney injury secondary to COVID-19 by peritoneal dialysis: Case report and literature review.
Authors: Al-Hwiesh AK, Mohammed AM, Elnokeety M, Al-Hwiesh A, Al-Audah N, Esam S, Abdul-Rahman IS Abstract Coronavirus Disease 2019 (COVID-19) is a pandemic disease that increased the burden on health-care system. In the Kingdom of Saudi Arabia, 74,795 cases have been reported until 26 May 2020 and the number of cases is rapidly increasing. The mortality rate of COVID-19 worldwide is 6.37%. Here we report three cases of acute kidney injury (AKI) secondary to pneumonia of severe COVID-19; they were treated with automated peritoneal dialysis (PD) with full recovery. To the best of our knowledge, few reports in the li...
Source: Peritoneal Dialysis International - October 3, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Wernicke encephalopathy: An unexpected cause of death in a peritoneal dialysis patient.
Authors: Duni A, Ikonomou M, Alekos J, Pappas C, Dounousi E PMID: 32990176 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 30, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

A simple novel device can provide independence for peritoneal dialysis patients.
Authors: Tanasiychuk T, Kushnir D, Vardi Y, Cohen-Hagai K, Zitman-Gal T, Frajewicki V, Benchetrit S, Einbinder Y PMID: 32964803 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 25, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Twenty-seven years of peritoneal dialysis with preserved peritoneal morphology: A case report with autopsy.
Authors: Oba R, Matsuo N, Honda Y, Furuya M, Maruyama Y, Tanno Y, Ohkido I, Yokoo T PMID: 32914693 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 13, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Different techniques for peritoneal dialysis catheter implantation: A systematic review and network meta-analysis.
The objective was to compare the efficacy and safety of PDC techniques by network meta-analysis (NMA). A systematic review of databases was conducted to identify eligible studies. NMA was used to estimate the ranking for endpoints. Our NMA included 41 studies (9 randomized controlled trials (RCTs) and 32 observational trials) and enrolled 3902 patients, comparing three techniques: the laparoscopic catheterization (LC), open surgery catheterization (OSC), and percutaneous catheterization (PC). NMA in RCTs showed OSC had the highest incidence of catheter mechanical dysfunction, PC and LC were very similar, but this result ha...
Source: Peritoneal Dialysis International - September 13, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Cerebral hemodynamics in peritoneal dialysis versus intermittent hemodialysis: A transcranial Doppler pilot study.
This study evaluated intradialytic cerebral hemodynamics measured by transcranial Doppler (TCD) in intermittent hemodialysis (iHD) versus nightly peritoneal dialysis (NIPD). Intradialytic TCD was serially performed in chronic dialysis patients receiving iHD (n = 10) and NIPD (n = 10). A linear mixed model was used to model mean flow velocity (MFV), pulsatility index (PI), and mean arterial pressure (MAP) as functions of time and treatment group. Intradialytic cerebral volatility (IDCV) was calculated using the coefficient of variation (CV) and mean absolute value of change (AVC) of each patient's MFV, PI, and MAP values ov...
Source: Peritoneal Dialysis International - September 12, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Exposition to glucose-based peritoneal dialysis fluids exacerbates adipocyte lipolysis and glycogen storage in rat adipose cells.
This study provides the first evidence that glucose-based dialysis solutions increase basal as well as stimulated lipolysis in adipocytes, an effect that is directly attributable to high concentrations of glucose per se. PMID: 32873148 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 5, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal dialysis for treatment of acute kidney injury in a case of paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2.
Authors: McCulloch M, Abugrain K, Mosalakatane T, Coetzee A, Webb K, Scott C Abstract This short report describes the case discussion of 9-year-old patient with acute kidney injury due to paediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 with successful peritoneal dialysis via a peritoneal dialysis catheter inserted at the bedside in an intensive care setting. PMID: 32875970 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 5, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Absence of SARS-CoV-2 in the effluent of peritoneal dialysis patients.
Authors: Candellier A, Scohy A, Gillet N, Muylkens B, Morelle J, Belkhir L, Coupeau D, Jadoul M, Goffin É Abstract The pandemic of respiratory disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is life-threatening in peritoneal dialysis (PD) patients. In PD patients with systemic viral infections, peritoneal effluent may be theoretically contaminated. We searched for the presence of SARS-CoV-2 genetic material by real-time reverse transcriptase-polymerase chain reaction assays in serial PD effluents of three PD infected patients. Nasopharyngeal swabs obtained at admissi...
Source: Peritoneal Dialysis International - September 3, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Chemokine receptors on peripheral blood T lymphocytes in children on peritoneal dialysis.
In conclusion, we could not confirm the phenomenon of earlier senescence of T-cells in children with CKD on PD treatment. This still requires further investigation. The higher percentage of T-cells with CCR7 surface receptor could be responsible for the increase of proliferation activity in this group of children. PMID: 32869708 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 3, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Intraperitoneal vancomycin for peritoneal dialysis-associated peritonitis in children: Evaluation of loading dose guidelines.
Authors: Hennessy K, Capparelli EV, Romanowski G, Alejandro L, Murray W, Benador N Abstract BACKGROUND: Current pediatric International Society for Peritoneal Dialysis guidelines for initial treatment of peritoneal dialysis (PD)-associated peritonitis suggest either monotherapy with cefepime or double therapy with first-generation cephalosporin or glycopeptide and ceftazidime or aminoglycoside. When using vancomycin, the intraperitoneal (IP) recommended pediatric loading dosage is 1000 mg/L of dialysate. This is based on adult pharmacokinetic (PK) studies and roughly translates to the adult recommendation where 30 ...
Source: Peritoneal Dialysis International - August 31, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Clinical utility of a traditional score system for the evaluation of the peritoneal dialysis exit-site infection in a national multicentric cohort study.
Authors: Rigo M, Pecoits-Filho R, Lambie M, Tuon FF, Barretti P, de Moraes TP Abstract INTRODUCTION: Exit-site infection (ESI) is an important risk factor for peritonitis in patients under chronic peritoneal dialysis (PD). The International Society for Peritoneal Dialysis (ISPD) recommend its diagnosis as the presence of purulent drainage in the exit site (ES) but time-consuming scores using others skin signs are routinely used. OBJECTIVE: To investigate the correlation between the diagnosis of ESI with a score based on five clinical signs obtained from ES inspection, and also if there are interaction with pati...
Source: Peritoneal Dialysis International - August 30, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Utility of serum beta-trace protein as a tool for estimating residual kidney function in peritoneal dialysis patients.
CONCLUSIONS: Serum BTP level was inversely related to RKF but neither BTP-estimated GFR equations were sufficiently accurate for routine use in PD patients. PMID: 32815791 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - August 21, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Tracking hydration status changes by bioimpedance spectroscopy in children on peritoneal dialysis.
Authors: Karava V, Stabouli S, Dotis J, Liakopoulos V, Papachristou F, Printza N Abstract BACKGROUND: This 6-month prospective longitudinal study investigates the association between hydration status changes using bioimpedance spectroscopy (BIS) and systolic blood pressure (SBP), pulse pressure (PP), and serum albumin (sAlb) changes in children on peritoneal dialysis (PD). METHODS: Thirteen patients (median age: 12.58 years) were enrolled. Normal hydration, moderate hydration, severe overhydration, and dehydration were defined as -7% ≤ relative overhydration (Re-OH)
Source: Peritoneal Dialysis International - August 14, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Tinea nigra palmaris-associated peritonitis, caused by Hortaea werneckii: The first case report in a peritoneal dialysis patient.
We report the first case of peritoneal dialysis (PD) patients with peritonitis from Hortaea werneckii, a halotolerant black yeast-like fungus. The pathogen was confirmed by nucleotide sequences of internal transcribed spacer regions of the ribosomal RNA gene. A potential cause of this infection was tinea nigra on the patient's palm. Therefore, gloving might be advised during PD bag exchange in patients or caregivers who have an obvious lesion of the palm. PMID: 32783526 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - August 14, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Burden in primary family caregivers caring for uremic patients on maintenance peritoneal dialysis.
CONCLUSION: Our study clearly showed that caring for patients with maintenance peritoneal dialysis caused physical, mental, and social burden in family caregivers, with the extent of the stress being influenced by patients' disease severity and other demographic factors in both patients and caregivers. PMID: 32735160 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - August 1, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Comparison of patient survival and technique survival between continuous ambulatory peritoneal dialysis and automated peritoneal dialysis.
CONCLUSIONS: The mortality risk was not significant between CAPD and APD patients. APD is associated with a lower risk of technique failure than CAPD, particularly for male patients, and patients aged 50-65 years, with diabetes, without CVD, with high or high average peritoneal permeability, or initiating PD in an earlier era. PMID: 32735162 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - August 1, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research