On the change of transport parameters with dwell time during peritoneal dialysis.
Authors: Waniewski J, Stachowska-Pietka J, Lindholm B Abstract The transitory change of fluid and solute transport parameters occurring during the initial phase of a peritoneal dialysis dwell is a well-documented phenomenon; however, its physiological interpretation is rather hypothetical and has been disputed. Two different explanations were proposed: (1) the prevailing view-supported by several experimental and clinical studies-is that a vasodilatory effect of dialysis fluid affects the capillary surface area available for dialysis, and (2) a recently presented alternative explanation is that the molecular radius...
Source: Peritoneal Dialysis International - November 18, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Digital health - The new reality. What does this mean for peritoneal dialysis?
Authors: Wilkie M PMID: 33176610 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - November 14, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal dialysis for acute kidney injury: Equations for dosing in pandemics, disasters, and beyond.
CONCLUSIONS: The equations are intended as a practical tool to estimate solute clearances and guide prescription of continuous PD. The estimated dialysate volume required for any dose target can be calculated from cycle duration or dwell volume. However, the exact target dose of PD is uncertain and should be adjusted according to the clinical circumstances and response to treatment. The equations presented in this article facilitate the adjustment of PD prescription toward the targeted solute clearance. PMID: 33174468 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - November 12, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Patient and caregiver perspectives on burnout in peritoneal dialysis.
CONCLUSIONS: For patients on PD and their caregivers, burnout was intensified by perceiving PD as an unrelenting, isolating responsibility that they had no choice but to endure, even if it held them back from doing other activities in life. More emphasis on developing strategies to adapt and build resilience could prevent or minimize burnout. PMID: 33174471 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - November 12, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal dialysis access outcomes reported in randomized controlled trials: A systematic review.
CONCLUSION: Variability exists in the definitions, reporting methods, choice of outcomes, and analysis of the PD access outcomes across RCTs. Operative-related outcomes remain underreported across RCTs. Outcomes relating to PD access flow restriction were the most common complications reported in the included RCTs but were reported heterogeneously with variability in reporting of the three key components of its definition including description and severity of the flow restriction, the need for intervention and etiology of flow restriction. In the future, defining PD access flow restriction should include all of these compo...
Source: Peritoneal Dialysis International - October 29, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Streptococcus salivarius peritonitis in an infant receiving chronic peritoneal dialysis.
We describe a 4-month-old male who developed S. salivarius peritonitis while receiving automated peritoneal dialysis and who was successfully treated with a 14-day course of intraperitoneal vancomycin. Subtyping episodes of S. viridans-related infection is essential for the identification of S. salivarius. PMID: 33084495 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 22, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Patients' and caregivers' expectations and experiences of remote monitoring for peritoneal dialysis: A qualitative interview study.
CONCLUSIONS: Remote monitoring may increase patient knowledge about their kidney disease and its treatment, encourage accountability to the clinical team, enhance partnerships with clinicians, and improve access to treatment and timely care. It is also important to ensure that remote monitoring does not replace face-to-face clinical contact with clinicians. PMID: 33084514 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 22, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Forty years of peritoneal dialysis Listeria peritonitis: Case and review.
We report a continuous cycling peritoneal dialysis (CCPD) patient who presented initially disseminated listeriosis with peritonitis. He was successfully treated with intraperitoneal and intravenous ampicillin but died unfortunately from a cardiorespiratory arrest due to food inhalation. It is the 20th case of such peritonitis mentioned among PD patients and the first reported in Belgium. This case illustrates the importance of a systematic approach to get quick diagnosis and effective antibiotic readjustment. Empiric therapy is not effective on Listeria which is naturally resistant to cephalosporins and poorly sensitive to...
Source: Peritoneal Dialysis International - October 9, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Corrigendum to A Randomized Controlled Trial to Determine the Appropriate Time to Initiate Peritoneal Dialysis after Insertion of Catheter (Timely PD Study).
Authors: PMID: 33025865 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 9, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Computerized adaptive technology for the assessment of HRQOL of PD and CKD patients.
This study was designed as a pilot study to see whether electronic patient-reported outcome measures using computer adaptive technology (CAT) could be successfully implemented in clinics caring for chronic kidney disease (CKD) and peritoneal dialysis (PD) patients. The results demonstrate the feasibility of using CAT on an iPad to assess the symptom burden and health-related quality of life of both PD and CKD patients. PMID: 33016231 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 6, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Rebuilding stronger - lessons from COVID-19.
Authors: Wilkie M PMID: 32998643 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 3, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Does SARS-CoV-2 reach peritoneal effluent?
Authors: Sadioglu RE, Aktar M, Gulten E, Eyupoglu S, Karahan ZC, Azap A, Sengul S, Ates K, Kutlay S PMID: 32998644 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - October 3, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Successfully treating three patients with acute kidney injury secondary to COVID-19 by peritoneal dialysis: Case report and literature review.
Authors: Al-Hwiesh AK, Mohammed AM, Elnokeety M, Al-Hwiesh A, Al-Audah N, Esam S, Abdul-Rahman IS Abstract Coronavirus Disease 2019 (COVID-19) is a pandemic disease that increased the burden on health-care system. In the Kingdom of Saudi Arabia, 74,795 cases have been reported until 26 May 2020 and the number of cases is rapidly increasing. The mortality rate of COVID-19 worldwide is 6.37%. Here we report three cases of acute kidney injury (AKI) secondary to pneumonia of severe COVID-19; they were treated with automated peritoneal dialysis (PD) with full recovery. To the best of our knowledge, few reports in the li...
Source: Peritoneal Dialysis International - October 3, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Wernicke encephalopathy: An unexpected cause of death in a peritoneal dialysis patient.
Authors: Duni A, Ikonomou M, Alekos J, Pappas C, Dounousi E PMID: 32990176 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 30, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

A simple novel device can provide independence for peritoneal dialysis patients.
Authors: Tanasiychuk T, Kushnir D, Vardi Y, Cohen-Hagai K, Zitman-Gal T, Frajewicki V, Benchetrit S, Einbinder Y PMID: 32964803 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 25, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Twenty-seven years of peritoneal dialysis with preserved peritoneal morphology: A case report with autopsy.
Authors: Oba R, Matsuo N, Honda Y, Furuya M, Maruyama Y, Tanno Y, Ohkido I, Yokoo T PMID: 32914693 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 13, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Different techniques for peritoneal dialysis catheter implantation: A systematic review and network meta-analysis.
The objective was to compare the efficacy and safety of PDC techniques by network meta-analysis (NMA). A systematic review of databases was conducted to identify eligible studies. NMA was used to estimate the ranking for endpoints. Our NMA included 41 studies (9 randomized controlled trials (RCTs) and 32 observational trials) and enrolled 3902 patients, comparing three techniques: the laparoscopic catheterization (LC), open surgery catheterization (OSC), and percutaneous catheterization (PC). NMA in RCTs showed OSC had the highest incidence of catheter mechanical dysfunction, PC and LC were very similar, but this result ha...
Source: Peritoneal Dialysis International - September 13, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Cerebral hemodynamics in peritoneal dialysis versus intermittent hemodialysis: A transcranial Doppler pilot study.
This study evaluated intradialytic cerebral hemodynamics measured by transcranial Doppler (TCD) in intermittent hemodialysis (iHD) versus nightly peritoneal dialysis (NIPD). Intradialytic TCD was serially performed in chronic dialysis patients receiving iHD (n = 10) and NIPD (n = 10). A linear mixed model was used to model mean flow velocity (MFV), pulsatility index (PI), and mean arterial pressure (MAP) as functions of time and treatment group. Intradialytic cerebral volatility (IDCV) was calculated using the coefficient of variation (CV) and mean absolute value of change (AVC) of each patient's MFV, PI, and MAP values ov...
Source: Peritoneal Dialysis International - September 12, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Exposition to glucose-based peritoneal dialysis fluids exacerbates adipocyte lipolysis and glycogen storage in rat adipose cells.
This study provides the first evidence that glucose-based dialysis solutions increase basal as well as stimulated lipolysis in adipocytes, an effect that is directly attributable to high concentrations of glucose per se. PMID: 32873148 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 5, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal dialysis for treatment of acute kidney injury in a case of paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2.
Authors: McCulloch M, Abugrain K, Mosalakatane T, Coetzee A, Webb K, Scott C Abstract This short report describes the case discussion of 9-year-old patient with acute kidney injury due to paediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 with successful peritoneal dialysis via a peritoneal dialysis catheter inserted at the bedside in an intensive care setting. PMID: 32875970 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 5, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Absence of SARS-CoV-2 in the effluent of peritoneal dialysis patients.
Authors: Candellier A, Scohy A, Gillet N, Muylkens B, Morelle J, Belkhir L, Coupeau D, Jadoul M, Goffin É Abstract The pandemic of respiratory disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is life-threatening in peritoneal dialysis (PD) patients. In PD patients with systemic viral infections, peritoneal effluent may be theoretically contaminated. We searched for the presence of SARS-CoV-2 genetic material by real-time reverse transcriptase-polymerase chain reaction assays in serial PD effluents of three PD infected patients. Nasopharyngeal swabs obtained at admissi...
Source: Peritoneal Dialysis International - September 3, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Chemokine receptors on peripheral blood T lymphocytes in children on peritoneal dialysis.
In conclusion, we could not confirm the phenomenon of earlier senescence of T-cells in children with CKD on PD treatment. This still requires further investigation. The higher percentage of T-cells with CCR7 surface receptor could be responsible for the increase of proliferation activity in this group of children. PMID: 32869708 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - September 3, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Intraperitoneal vancomycin for peritoneal dialysis-associated peritonitis in children: Evaluation of loading dose guidelines.
Authors: Hennessy K, Capparelli EV, Romanowski G, Alejandro L, Murray W, Benador N Abstract BACKGROUND: Current pediatric International Society for Peritoneal Dialysis guidelines for initial treatment of peritoneal dialysis (PD)-associated peritonitis suggest either monotherapy with cefepime or double therapy with first-generation cephalosporin or glycopeptide and ceftazidime or aminoglycoside. When using vancomycin, the intraperitoneal (IP) recommended pediatric loading dosage is 1000 mg/L of dialysate. This is based on adult pharmacokinetic (PK) studies and roughly translates to the adult recommendation where 30 ...
Source: Peritoneal Dialysis International - August 31, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Clinical utility of a traditional score system for the evaluation of the peritoneal dialysis exit-site infection in a national multicentric cohort study.
Authors: Rigo M, Pecoits-Filho R, Lambie M, Tuon FF, Barretti P, de Moraes TP Abstract INTRODUCTION: Exit-site infection (ESI) is an important risk factor for peritonitis in patients under chronic peritoneal dialysis (PD). The International Society for Peritoneal Dialysis (ISPD) recommend its diagnosis as the presence of purulent drainage in the exit site (ES) but time-consuming scores using others skin signs are routinely used. OBJECTIVE: To investigate the correlation between the diagnosis of ESI with a score based on five clinical signs obtained from ES inspection, and also if there are interaction with pati...
Source: Peritoneal Dialysis International - August 30, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Utility of serum beta-trace protein as a tool for estimating residual kidney function in peritoneal dialysis patients.
CONCLUSIONS: Serum BTP level was inversely related to RKF but neither BTP-estimated GFR equations were sufficiently accurate for routine use in PD patients. PMID: 32815791 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - August 21, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Tracking hydration status changes by bioimpedance spectroscopy in children on peritoneal dialysis.
Authors: Karava V, Stabouli S, Dotis J, Liakopoulos V, Papachristou F, Printza N Abstract BACKGROUND: This 6-month prospective longitudinal study investigates the association between hydration status changes using bioimpedance spectroscopy (BIS) and systolic blood pressure (SBP), pulse pressure (PP), and serum albumin (sAlb) changes in children on peritoneal dialysis (PD). METHODS: Thirteen patients (median age: 12.58 years) were enrolled. Normal hydration, moderate hydration, severe overhydration, and dehydration were defined as -7% ≤ relative overhydration (Re-OH)
Source: Peritoneal Dialysis International - August 14, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Tinea nigra palmaris-associated peritonitis, caused by Hortaea werneckii: The first case report in a peritoneal dialysis patient.
We report the first case of peritoneal dialysis (PD) patients with peritonitis from Hortaea werneckii, a halotolerant black yeast-like fungus. The pathogen was confirmed by nucleotide sequences of internal transcribed spacer regions of the ribosomal RNA gene. A potential cause of this infection was tinea nigra on the patient's palm. Therefore, gloving might be advised during PD bag exchange in patients or caregivers who have an obvious lesion of the palm. PMID: 32783526 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - August 14, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Burden in primary family caregivers caring for uremic patients on maintenance peritoneal dialysis.
CONCLUSION: Our study clearly showed that caring for patients with maintenance peritoneal dialysis caused physical, mental, and social burden in family caregivers, with the extent of the stress being influenced by patients' disease severity and other demographic factors in both patients and caregivers. PMID: 32735160 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - August 1, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Comparison of patient survival and technique survival between continuous ambulatory peritoneal dialysis and automated peritoneal dialysis.
CONCLUSIONS: The mortality risk was not significant between CAPD and APD patients. APD is associated with a lower risk of technique failure than CAPD, particularly for male patients, and patients aged 50-65 years, with diabetes, without CVD, with high or high average peritoneal permeability, or initiating PD in an earlier era. PMID: 32735162 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - August 1, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Impact of time-varying center volume on technique failure and mortality in peritoneal dialysis.
CONCLUSIONS: Receiving PD in high-volume facilities was associated with a lower risk in technique failure. No association was found between facility volume and mortality risk. PMID: 32729780 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - July 31, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Management of peritoneal dialysis under COVID-19: The experience in Sichuan Province People's Hospital, China.
Authors: Chen J, Yin L, Chen X, Gao H, Zhou Q, Li P, Liu W, Ding H, Hong D, Li G, Wang L Abstract The outbreak of coronavirus disease 2019 (COVID-19) is becoming a severe challenge to China and the whole world. By now, there is no report about medical support to peritoneal dialysis (PD) patient during COVID-19 pandemic. In this essay, we summed up our safety measures on how to protect PD patients and our staffs, and our experience on how to ensure the dialysis treatment of PD patients during the pandemic period. Using of telehealth has potential to improve patient care quality. As a result, by applying all the acti...
Source: Peritoneal Dialysis International - July 28, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Aortic stenosis in patients with kidney failure: Is there an advantage for a PD-first policy?
Authors: Candellier A, Hénaut L, Morelle J, Choukroun G, Jadoul M, Brazier M, Goffin É Abstract Aortic stenosis (AS) is the most common valvular disease. It is twice as prevalent in patients with kidney failure as compared to the general population. In addition, AS progresses at a faster rate and is associated with a higher risk of death and poorer quality of life in patients on dialysis. Chronic kidney disease-mineral and bone disorder (CKD-MBD), inflammation, and hemodynamic disturbances contribute to the pathophysiology and progression of AS. Whether the type of dialysis modality, that is, hemodial...
Source: Peritoneal Dialysis International - July 21, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Peritoneal fibrosis and epigenetic modulation.
Authors: Wang Y, Shi Y, Tao M, Zhuang S, Liu N Abstract Peritoneal dialysis (PD) is an effective treatment for patients with end-stage renal disease. However, peritoneal fibrosis (PF) is a common complication that ultimately leads to ultrafiltration failure and discontinuation of PD after long-term PD therapy. There is currently no effective therapy to prevent or delay this pathologic process. Recent studies have reported epigenetic modifications involved in PF, and accumulating evidence suggests that epigenetic therapies may have the potential to prevent and treat PF clinically. The major epigenetic modifications ...
Source: Peritoneal Dialysis International - July 15, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Remote patient management of peritoneal dialysis during COVID-19 pandemic.
Authors: Ronco C, Manani SM, Giuliani A, Tantillo I, Reis T, Brown EA PMID: 32597314 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - July 1, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Nomenclature for Kidney Function and Disease: Executive Summary and Glossary From a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference.
This article is being published in Kidney International Reports and reprinted concurrently in several journals. The articles cover identical concepts and wording but vary in minor stylistic and spelling changes, detail, and length of manuscript, in keeping with each journal's style. Any of these versions may be used in citing this article. Excerpts are adapted with permission of KDIGO and the International Society of Nephrology. PMID: 32597692 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - July 1, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Saving more young lives in Africa.
Authors: Cullis B, Lalya F, Smoyer WE PMID: 32552403 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - June 21, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Acute peritoneal dialysis in COVID-19.
Authors: Parapiboon W, Ponce D, Cullis B PMID: 32552550 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - June 21, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Contrast-enhanced ultrasound: A novel diagnostic approach for the detection of peritoneal dialysis catheter leakages.
Authors: Ksiazek SH, Schuster H, Säemann MD, Vychytil A, Göndör G PMID: 32546055 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - June 18, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Treatments and outcomes of encapsulating peritoneal sclerosis in patients undergoing peritoneal dialysis: 295 cases from a nationwide inpatient database in Japan.
Authors: Konishi T, Fujiogi M, Michihata N, Morita K, Matsui H, Fushimi K, Tanabe M, Seto Y, Yasunaga H Abstract BACKGROUND: The number of patients undergoing renal replacement therapy is increasing. We evaluated the practice patterns and outcomes of encapsulating peritoneal sclerosis (EPS) in patients undergoing peritoneal dialysis. METHODS: Using a Japanese national inpatient database, we identified 295 patients with EPS who were hospitalized from July 2010 to March 2017. We categorized them into four groups: those who underwent surgery only (n = 39), those who received corticosteroid treatment only (n = 70),...
Source: Peritoneal Dialysis International - June 11, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Effect of uric acid levels on mortality in Japanese peritoneal dialysis patients.
Authors: Sugano N, Maruyama Y, Ohno I, Wada A, Shigematsu T, Masakane I, Yokoo T, Nitta K Abstract BACKGROUND: Unlike the situation in the general population, most studies of patients receiving hemodialysis have reported lower uric acid (UA) as associated with higher mortality. However, the relationship between UA level and mortality remains unclear among patients receiving peritoneal dialysis (PD). METHODS: We collected baseline data for 4742 prevalent PD patients (age, 63 ± 14 years; male, 61.5%; diabetes, 29.1%; median dialysis duration, 28 months) from a nationwide dialysis registry in Japan at the e...
Source: Peritoneal Dialysis International - June 7, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Ten-year survival of patients treated with peritoneal dialysis: A prospective observational cohort study.
CONCLUSIONS: The 10-year's survival and technique survival rates of incident PD patients were 36% and 62%. Long-term PD can be continued successfully with improved outcomes and low risk for EPS. PMID: 32489134 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - June 4, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Surgical correction of hydrothorax complicating pediatric peritoneal dialysis.
We present 2 pediatric cases who underwent successful direct surgical repair of diaphragmatic defects using VATS with return to CCPD. Initial approach with VATS should be strongly considered in patients in whom a lifetime change in modality has significant repercussions. PMID: 32431210 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 22, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Mycobacterium septicum associated peritonitis: A case report.
We report the first case of PD-associated peritonitis secondary to Mycobacterium septicum. The patient is a 53-year-old Caucasian man who developed end-stage kidney disease due to systemic sclerosis. He was initially started on intermittent hemodialysis and was then switched to PD 10 months later. He presented with generalized abdominal pain and an increase in the number of nucleated cells and neutrophils in the dialysate effluent sample (854 total nucleated cells/µL and 512 neutrophils/µL). Ten days later, the fluid grew M. septicum, a rapidly growing nontuberculous mycobacterium (NTM). Once the organism was i...
Source: Peritoneal Dialysis International - May 21, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Single-dwell treatment with a low-sodium solution in hypertensive peritoneal dialysis patients.
CONCLUSIONS: Superiority of low-Na PD solution over standard-Na solution for control of BP could not be shown. The once daily use of a low-Na PD solution was associated with more hypotensive episodes, suggesting the need to reassess the overall concept of how Na-reduced solutions might be incorporated within the treatment schedule. PMID: 32425111 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 21, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Salvation of peritoneal dialysis catheter potency by using an angiographic guidewire.
In this report, we present two cases of catheter obstruction caused by intraluminal clots of PD catheter. The clots, which could not be removed by the conservative management, were removed by a new technique using an angiographic guidewire. The technique could be an option to resolve PD catheter obstruction. PMID: 32425132 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 21, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Nontuberculous mycobacteria infections of peritoneal dialysis patients: A multicenter study.
CONCLUSIONS: Culture negative peritonitis, isolation of diphtheroids or Corynebacterium spp., previous exposure to antibiotics, and/or a refractory infection should all prompt consideration of PD-related NTM infection and timely workup. Catheter removal is recommended aside prolonged antimicrobial therapy. In select patients with ESI, continuation of PD may be feasible. PMID: 32400280 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 15, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Salvage of the peritoneal dialysis catheter in Candida peritonitis using amphotericin B catheter lock.
This study confirms our previous findings that an amphotericin B lock-based protocol has potential to cure Candida peritonitis without PD catheter removal. However, further research is needed given the limitations of this study. Until that time, the lock-based Candida protocol could be used in patients who are not severely ill and in whom PD catheter removal is not desirable. PMID: 32400305 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 15, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

High alkaline phosphatase and low intact parathyroid hormone associate with worse clinical outcome in peritoneal dialysis patients.
CONCLUSIONS: The combination of high ALP and low iPTH was independently associated with increased all-cause and cardiovascular mortality in PD patients, suggesting that ALP and iPTH have the potential to predict clinical outcomes and might be useful risk assessment tools in PD patients. Further studies exploring the observed association between combination of ALP with iPTH and mortality are warranted. PMID: 32363998 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 5, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Prescribing peritoneal dialysis - a new guideline from the International Society of Peritoneal Dialysis.
Authors: Wilkie M PMID: 32352356 [PubMed - in process] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - May 2, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

Use of locally prepared peritoneal dialysis (PD) fluid for acute PD in children and infants in Africa.
CONCLUSIONS: Locally prepared PD solutions at the bedside adapted from intravenous solutions can be used safely and effectively. This has important relevance for centres in less well-resourced countries, where commercially produced PD fluid is not available for the management of AKI. PMID: 32323622 [PubMed - as supplied by publisher] (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - April 25, 2020 Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research