Comparative simulation of intraperitoneal aminoglycoside regimens for patients with peritonitis on automated peritoneal dialysis
CONCLUSIONS: The current international guidelines for the treatment of peritoneal dialysis-associated peritonitis can continue to recommend the fixed-dose regimen for those on APD with the addition of plasma Cmin monitoring after 3 days to assess for drug accumulation.PMID:38288583 | DOI:10.1177/08968608231221062 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - January 30, 2024 Category: Urology & Nephrology Authors: Robert E Ariano Sheryl A Zelenitsky Christine Davis Christie Sathianathan William R Wolowich Source Type: research

PD peritonitis in patients undergoing capsule endoscopy: A descriptive study
The objective of the study was to assess the risk of PD peritonitis in patients undergoing CE. Descriptive statistics were used to describe patient characteristics and clinical outcomes. Overall, 23 patients with PD underwent CE. Twelve patients underwent CE alone (i.e. no other concomitant procedures) and none of these patients experienced an episode of PD peritonitis. The remaining 11 patients underwent CE and other invasive endoscopic/abdominal surgical procedures, of whom 2 suffered PD peritonitis. CE is likely a relatively safe procedure in PD patients. PD patients undergoing CE may not require prior antibiotic prophy...
Source: Peritoneal Dialysis International - January 30, 2024 Category: Urology & Nephrology Authors: Mina Khair Dharmenaan Palamuthusingam Carmel M Hawley Elaine M Pascoe David Wayne Johnson Saw Yu Mon Magid Fahim Source Type: research

COVID-19 and outcomes in Chinese peritoneal dialysis patients
CONCLUSIONS: Although vaccinated patients were more likely to have tested positive for COVID-19 infection, they appeared to have less severe infection and less need for hospitalisation. Patients who were older with a history of hyponatremia were more likely to experience adverse outcomes from COVID-19.PMID:38265011 | DOI:10.1177/08968608231221952 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - January 24, 2024 Category: Urology & Nephrology Authors: Ruoxi Liao Xueli Zhou Dengyan Ma Shaofen Wang Ping Fu Hui Zhong Source Type: research

Percutaneous endoscopic gastrostomy in children receiving peritoneal dialysis: A tertiary centre long-term experience and literature review
CONCLUSIONS: Based on our experience, our technique of PEG insertion with antimicrobial prophylaxis is feasible and associated with an acceptable complication risk in patients on PD. Further multicentric studies about surgical technique in patients on PD will be necessary to verify the feasibility of PEG and standardise the perioperative protocol.PMID:38265012 | DOI:10.1177/08968608231223812 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - January 24, 2024 Category: Urology & Nephrology Authors: Federica Fati Rebecca Pulvirenti Germana Longo Luca Maria Antoniello Elisa Zambaiti Piergiorgio Gamba Source Type: research

The role of peritoneal dialysis in the treatment of acute kidney injury in neurocritical patients: a retrospective Brazilian study
CONCLUSION: Our study suggests that careful prescription may contribute to providing adequate treatment for most neurocritical AKI patients without contraindications for PD use, allowing adequate metabolic and fluid control, with no increase in the number of infectious, mechanical and metabolic complications. Mechanical ventilation, positive fluid balance and intracerebral haemorrhage were factors associated with mortality, while patients with nephrotoxic AKI had lower odds of mortality compared to those with septic and ischaemic AKI. Further studies are needed to investigate better the role of PD in neurocritical patients...
Source: Peritoneal Dialysis International - January 24, 2024 Category: Urology & Nephrology Authors: Daniela Ponce Gonzalo Ram írez-Guerrero Andr é Luis Balbi Source Type: research

Why should we use a low sodium dialysis solution for peritoneal dialysis?
Perit Dial Int. 2024 Jan 24:8968608231222141. doi: 10.1177/08968608231222141. Online ahead of print.ABSTRACTOverhydration is highly prevalent in patients on peritoneal dialysis (PD), with inappropriately high sodium load supposedly playing a central role in the pathophysiology of the conditions. Recent studies have revealed the novel role of the interstitium as a buffer system for sodium ions, and it has been reported that patients on dialysis, including PD, present increased levels of sodium in the interstitium, such as in subcutaneous tissue and muscle. Hence, therapy for correction of overhydration should target the exc...
Source: Peritoneal Dialysis International - January 24, 2024 Category: Urology & Nephrology Authors: Masaaki Nakayama Source Type: research

The Peritoneal Dialysis Surprise Question and Technique Survival: Are you surprised?
Perit Dial Int. 2024 Jan;44(1):3-5. doi: 10.1177/08968608231223291.NO ABSTRACTPMID:38192083 | DOI:10.1177/08968608231223291 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - January 9, 2024 Category: Urology & Nephrology Authors: Osama El Shamy Source Type: research

Is health-related quality of life trajectory associated with dialysis modality choice in advanced chronic kidney disease?
CONCLUSIONS: Patients choosing home dialysis had improved MCS over time compared to those not selecting home dialysis. More work is needed to determine how differences in processes of care and/or unmeasured patient characteristics modulate this association.PMID:38186013 | DOI:10.1177/08968608231217807 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - January 8, 2024 Category: Urology & Nephrology Authors: Catherine Morin Maude Pichette Naoual Elftouh Benoit Imbeault Louis-Philippe Laurin Jean-Philippe Lafrance R émi Goupil Annie-Claire Nadeau-Fredette Source Type: research

The Point-of-Care Peritoneal Dialysis System Early Evaluation Study (POC-PDEE): A pilot proof-of-principal study of the Ellen Medical Devices Point-of-Care affordable peritoneal dialysis system
Perit Dial Int. 2024 Jan 5:8968608231209850. doi: 10.1177/08968608231209850. Online ahead of print.ABSTRACTThe global unmet need for kidney replacement therapy means that millions of people die every year as they cannot afford treatment. Peritoneal dialysis (PD) offers comparable survival to haemodialysis and is often more affordable, but one barrier to increasing access is that conventional manufacturing and distribution of PD fluid is costly. Here we report the results from a pilot proof-of-principal study demonstrating for the first time that the Ellen Medical Devices Point-of-Care system can be used by patients to prod...
Source: Peritoneal Dialysis International - January 5, 2024 Category: Urology & Nephrology Authors: Benjamin Talbot Simon Davies Jenny Burman Angus Ritchie Paul Snelling Sue Lynch Youn Park Brian Jones Vincent Garvey Allison Jaure Meg Jardine Vlado Perkovic Martin Gallagher Arthur Brandwood Navneet Kaur John Knight Source Type: research

Relationship between number of daily exchanges at CAPD start with clinical outcomes
CONCLUSIONS: One- or two-exchange CAPD start was associated with a lower risk of peritonitis in comparison to three- or four-exchange start. Furthermore, an initial PD prescription with less than three exchanges may be associated with an advantage in term of hospitalisation rate and patient survival.PMID:38115700 | DOI:10.1177/08968608231209849 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - December 20, 2023 Category: Urology & Nephrology Authors: Luca Nardelli Antonio Scalamogna Elisa Cicero Federica Tripodi Simone Vettoretti Carlo Alfieri Giuseppe Castellano Source Type: research

Sterility of antibiotic-admixed peritoneal dialysis solution over time
CONCLUSIONS: Antibiotic-admixed PD solutions prepared using AT and stored at room temperature remained sterile for up to 72 h. This suggests that patients can be safely issued with a supply of antibiotic-admixed PD bags for up to three days at a time.PMID:38115707 | DOI:10.1177/08968608231213736 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - December 20, 2023 Category: Urology & Nephrology Authors: Ken-Soon Tan Robyn Rogers Deanna Shephard Amanda Lewis Narelle George David W Johnson Source Type: research