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Peer review chair report: Association of Chiropractic Colleges Educational Conference and Research Agenda Conference 2023 peer review process
CONCLUSION: Overall, peer reviewer satisfaction with the process used for the 2023 ACC-RAC was high. We will include information from this report as part of the continuous quality improvement of peer review process, an important part of improving chiropractic education, research, and scholarly activities.PMID:37721857 | DOI:10.7899/JCE-23-20
Source: The Journal of Chiropractic Education - September 18, 2023 Category: Complementary Medicine Authors: Claire Johnson Source Type: research

Prevalence of neck pain and its associated factors in Africa: a systematic review and meta-analysis protocol
Discussion This will be the first systematic review and meta-analysis to systematically identify and synthesise available literature on the prevalence of neck pain and its associated factors in Africa. The results of this review may assist health professionals and policymakers to plan and implement evidence-based strategies that will lessen the burden of neck pain. Ethics and dissemination Data from previously published studies will be collected and analysed and hence ethical approval will not be sought for this study. The results of this review will be disseminated through publication in a peer-reviewed academic journal ...
Source: BMJ Open - September 18, 2023 Category: General Medicine Authors: Mukhtar, N. B., Ibrahim, A. A., Mohammed, J. Tags: Open access, Epidemiology Source Type: research

Ethical Requirements for Human Challenge Studies: A Systematic Review of Reasons
Clin Pharmacol Ther. 2023 Sep 16. doi: 10.1002/cpt.3054. Online ahead of print.ABSTRACTHuman challenge studies (HCS) are controlled clinical trials in which participants are deliberately infected with a pathogen. Such trials are being developed for an increasing number of diseases. Partly as a result of the COVID-19 pandemic, there has been a recent ethical debate about the reasons for and against HCS in general, or rather, about the requirements that individual HCS must fulfill to be ethically acceptable. A systematic review was conducted to categorize and summarize such requirements and the reasons given for them. Ethics...
Source: Clinical Pharmacology and Therapeutics - September 16, 2023 Category: Drugs & Pharmacology Authors: Matthias Katzer Sabine Salloch Christoph Schindler Marcel Mertz Source Type: research

Interventions promoting recovery from depression for patients transitioning from outpatient mental health services to primary care: Protocol for a scoping review
DiscussionThe chosen methodology is based on the use of publicly available information and does not require ethical approval. Results will be published in an international peer reviewed scientific journal, at national and international conferences and shared with relevant authorities. RegistrationA pre-print has been registered at the medRxiv preprint server for health sciences (doi.org/10.1101/2022.10.06.22280499).
Source: PLoS One - September 15, 2023 Category: Biomedical Science Authors: Anne Sofie Aggestrup Source Type: research

Protocol for a systematic review and meta-analysis of tobacco-cessation interventions delivered perioperatively
Introduction Tobacco smoking is associated with a substantially increased risk of perioperative complications. The perioperative period is an opportunity to introduce tobacco-cessation strategies. A previous systematic review provided evidence that perioperative interventions increase short-term abstinence and may reduce postoperative complications. The evidence base has since expanded, with the subsequent publication of numerous randomised studies. This protocol outlines a systematic review examining the impact of perioperative tobacco-cessation interventions on successful abstinence from tobacco smoking, and on the incid...
Source: BMJ Open - September 15, 2023 Category: General Medicine Authors: Harrogate, S. R., Barnes, J. D., Gupta, S., Rudd, S., Banerjee, T., Thomas, K., Hinchliffe, R., Mouton, R. Tags: Open access, Anaesthesia Source Type: research

Cryotherapy following total knee replacement
CONCLUSIONS: The certainty of evidence was low for blood loss, pain and range of motion, and very low for transfusion rate, function, total adverse events and withdrawals from adverse events. We are uncertain whether cryotherapy improves transfusion rate, function, total adverse events or withdrawals from adverse events. We downgraded evidence for bias, indirectness, imprecision and inconsistency. Hence, the potential benefits of cryotherapy on blood loss, pain and range of motion may be too small to justify its use. More well-designed randomised controlled trials focusing especially on clinically meaningful outcomes, such...
Source: Cochrane Database of Systematic Reviews - September 14, 2023 Category: General Medicine Authors: Ashwin Aggarwal Sam Adie Ian A Harris Justine Naylor Source Type: research

Hesperidin: Enrichment, forced degradation, and structural elucidation of potential degradation products using spectral techniques
CONCLUSIONS: Hesperidin was labile under acidic and basic stress conditions. The potential DPs were characterized using LC-ESI-MS/MS and NMR spectral techniques. The proposed mechanism of formation was hypothesized. In addition, to identify and characterize the DPs, a SIAM, which has broad biomedical applications, was successfully developed.PMID:37706431 | DOI:10.1002/rcm.9615
Source: Rapid Communications in Mass Spectrometry : RCM - September 14, 2023 Category: Chemistry Authors: Amol Chhatrapati Bisen Priyanka Rawat Gaurav Sharma Sachin Nashik Sanap Sristi Agrawal Shiv Kumar Ashok Kumar Abhijit Deb Choudhury Sakshi Kamboj Tadigoppula Narender Sanjeev K Shukla Sanjeev Kanojiya Rabi Sankar Bhatta Source Type: research

Cryotherapy following total knee replacement
CONCLUSIONS: The certainty of evidence was low for blood loss, pain and range of motion, and very low for transfusion rate, function, total adverse events and withdrawals from adverse events. We are uncertain whether cryotherapy improves transfusion rate, function, total adverse events or withdrawals from adverse events. We downgraded evidence for bias, indirectness, imprecision and inconsistency. Hence, the potential benefits of cryotherapy on blood loss, pain and range of motion may be too small to justify its use. More well-designed randomised controlled trials focusing especially on clinically meaningful outcomes, such...
Source: Cochrane Database of Systematic Reviews - September 14, 2023 Category: General Medicine Authors: Ashwin Aggarwal Sam Adie Ian A Harris Justine Naylor Source Type: research

Trauma-Informed Care in Medical Imaging and Radiation Therapy to Reduce Retraumatization
CONCLUSION: Because many aspects of care, including routine care in medical imaging and radiation therapy, can be an unintentional reminder of a traumatic experience, health care professionals should be trauma-informed when they are interacting with and caring for patients.PMID:37709517
Source: Radiologic Technology - September 14, 2023 Category: Radiology Authors: Kevin R Clark Jennifer S Sonsiadek Source Type: research

Hesperidin: Enrichment, forced degradation, and structural elucidation of potential degradation products using spectral techniques
CONCLUSIONS: Hesperidin was labile under acidic and basic stress conditions. The potential DPs were characterized using LC-ESI-MS/MS and NMR spectral techniques. The proposed mechanism of formation was hypothesized. In addition, to identify and characterize the DPs, a SIAM, which has broad biomedical applications, was successfully developed.PMID:37706431 | DOI:10.1002/rcm.9615
Source: Rapid Communications in Mass Spectrometry : RCM - September 14, 2023 Category: Chemistry Authors: Amol Chhatrapati Bisen Priyanka Rawat Gaurav Sharma Sachin Nashik Sanap Sristi Agrawal Shiv Kumar Ashok Kumar Abhijit Deb Choudhury Sakshi Kamboj Tadigoppula Narender Sanjeev K Shukla Sanjeev Kanojiya Rabi Sankar Bhatta Source Type: research

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