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Total 283 results found since Jan 2013.

Psychological factors and DNA methylation of genes related to immune/inflammatory system markers: the VA Normative Aging Study
Conclusions These findings suggest that positive and negative psychological factors affect DNA methylation of selected genes involved in chronic immune/inflammatory processes and inflammation-related endothelial dysfunction. Such epigenetic changes may represent biological pathways that mediate the effects of psychological factors on CHD.
Source: BMJ Open - January 5, 2016 Category: Journals (General) Authors: Kim, D., Kubzansky, L. D., Baccarelli, A., Sparrow, D., Spiro, A., Tarantini, L., Cantone, L., Vokonas, P., Schwartz, J. Tags: Open access, Epidemiology, Public health Research Source Type: research

How to prevent diabetes from sneaking up on your patients
An AMA Viewpoints post by AMA Board Chair Stephen R. Permut, MD A major health threat has been silently taking hold of 86 million Americans, with 90 percent of them unaware of it. A new public health campaign is about to change that—and you’re the key to helping these patients take their health back. A campaign to prevent type 2 diabetes If you’re not already talking to your patients about prediabetes and the risks associated with it, it’s time to start. People with prediabetes—more than 1 in 3 adults—are at higher risk of developing serious health problems such as type 2 diabetes, heart disease and s...
Source: AMA Wire - January 21, 2016 Category: Journals (General) Authors: Amy Farouk Source Type: news

Cohort profile: the Finnish Medication and Alzheimer's disease (MEDALZ) study
Purpose The aim of the Medicine use and Alzheimer's disease (MEDALZ) study is to investigate the changes in medication and healthcare service use among persons with Alzheimer's disease (AD) and to evaluate the safety and effectiveness of medications in this group. This is important, because the number of persons with AD is rapidly growing and even though they are a particularly vulnerable patient group, the number of representative, large-scale studies with adequate follow-up time is limited. Participants MEDALZ contains all residents of Finland who received a clinically verified diagnosis of AD between 2005 and 2011 and ...
Source: BMJ Open - July 12, 2016 Category: Journals (General) Authors: Tolppanen, A.-M., Taipale, H., Koponen, M., Lavikainen, P., Tanskanen, A., Tiihonen, J., Hartikainen, S. Tags: Open access, Epidemiology, Neurology, Pharmacology and therapeutics Cohort profile Source Type: research

Disability in Singapore's Elderly Population.
CONCLUSION: The findings highlighted specific factors associated with disability in this multiethnic population. The identification of these factors would lead the way to the development of appropriate interventions. PMID: 27523509 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - June 30, 2016 Category: Journals (General) Authors: Mahesh M, Abdin E, Vaingankar JA, Picco L, Jeyagurunathan A, Shafie SB, Pang S, Sagayadevan V, Seow E, Chong SA, Subramaniam M Tags: Ann Acad Med Singapore Source Type: research

Population-level interventions in government jurisdictions for dietary sodium reduction.
CONCLUSIONS: Population-level interventions in government jurisdictions for dietary sodium reduction have the potential to result in population-wide reductions in salt intake from pre-intervention to post-intervention, particularly if they are multi-component (more than one intervention activity) and incorporate intervention activities of a structural nature (e.g. food product reformulation), and particularly amongst men. Heterogeneity across studies was significant, reflecting different contexts (population and setting) and initiative characteristics. Implementation of future initiatives should embed more effective means ...
Source: Cochrane Database of Systematic Reviews - September 15, 2016 Category: Journals (General) Authors: McLaren L, Sumar N, Barberio AM, Trieu K, Lorenzetti DL, Tarasuk V, Webster J, Campbell NR Tags: Cochrane Database Syst Rev Source Type: research

Investigation of social, demographic and health variations in the usage of prescribed and over-the-counter medicines within a large cohort (South Yorkshire, UK)
Conclusions Our study addresses a dearth of evidence to provide new insights into how behaviours in medicine usage vary by demographic, social and health-related factors. Differences in over-the-counter medicine usage by educational attainment may help our understanding of the determinants of health inequalities.
Source: BMJ Open - September 27, 2016 Category: Journals (General) Authors: Green, M. A., Little, E., Cooper, R., Relton, C., Strong, M. Tags: Open access, Epidemiology, Public health Research Source Type: research

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980 –2015: a systematic analysis for the Global Burden of Disease Study 2015
Publication date: 8–14 October 2016 Source:The Lancet, Volume 388, Issue 10053 Author(s): GBD 2015 Mortality and Causes of Death CollaboratorsHaidongWangMohsenNaghaviChristineAllenRyan MBarberZulfiqar ABhuttaAustinCarterDaniel CCaseyFiona JCharlsonAlan ZianChenMatthew MCoatesMeganCoggeshallLalitDandonaDaniel JDickerHolly EErskineAlize JFerrariChristinaFitzmauriceKyleForemanMohammad HForouzanfarMaya SFraserNancyFullmanPeter WGethingEllen MGoldbergNicholasGraetzJuanita AHaagsmaSimon IHayChantalHuynhCatherine OJohnsonNicholas JKassebaumYohannesKinfuXie RachelKulikoffMichaelKutzHmwe HKyuHeidi JLarsonJanniLeungXiaofengLiangS...
Source: The Lancet - October 6, 2016 Category: Journals (General) Source Type: research

Hospital-diagnosed atopic dermatitis and long-term risk of myocardial infarction: a population-based follow-up study
Conclusions Hospital-diagnosed AD was associated with increased risk of MI compared with the general population.
Source: BMJ Open - November 10, 2016 Category: Journals (General) Authors: Riis, J. L., Vestergaard, C., Hjuler, K. F., Iversen, L., Jakobsen, L., Deleuran, M. S., Olsen, M. Tags: Open access, Cardiovascular medicine, Dermatology Research Source Type: research

Ideal cardiovascular health score and incident end-stage renal disease in a community-based longitudinal cohort study: the Kailuan Study
Conclusions A low CVH score significantly increased the risk of incident ESRD. Risk factors for cardiovascular events may also be associated with an increased risk for kidney failure.
Source: BMJ Open - November 28, 2016 Category: Journals (General) Authors: Han, Q. L., Wu, S. L., Liu, X. X., An, S. S., Wu, Y. T., Gao, J. S., Chen, S. H., Liu, X. K., Zhang, Q., Mao, R. Y., Shang, X. M., Jonas, J. B. Tags: Open access, Cardiovascular medicine, Epidemiology, Nutrition and metabolism, Occupational and environmental medicine, Renal medicine Research Source Type: research

Prevalence and Risk Factors of Caregiver Dependence among Older Adults in a Southeast Asian Population.
CONCLUSION: Various sociodemographic and health-related conditions were significantly associated with caregiver dependence. Dependent older adults will put greater demands on health and social services, resulting in greater healthcare expenditures. Hence, effective planning, services and support are crucial to meet the needs of dependent older adults and their caregivers. PMID: 27922142 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - October 31, 2016 Category: Journals (General) Authors: Picco L, Abdin E, Vaingankar JA, Pang S, Shafie S, Sambasivam R, Chong SA, Subramaniam M Tags: Ann Acad Med Singapore Source Type: research

An education programme influencing health professionals to recommend exercise to their type 2 diabetes patients – understanding the processes: a case study from Oxfordshire, UK
Increasing levels of physical activity decreases the risk of premature mortality associated with chronic diseases e.g., coronary heart disease, type 2 diabetes, stroke. Despite this, most adults in England do ...
Source: BMC Health Services Research - February 11, 2017 Category: Journals (General) Authors: Anne Matthews, Natasha Jones, Alastair Thomas, Perdy van den Berg and Charlie Foster Source Type: research

More to science: working in Business Management
What is your scientific background? I was conferred my PhD in Neuroscience from the Georgetown University Medical Center (GUMC) Interdisciplinary Program in Neuroscience (IPN). I studied central nervous system trauma in rodent models of contusive spinal cord injury. Judy Lytle My thesis centered on a specific type of progenitor cell, and its role in post-injury adult spinal cord tissue. I worked to characterize this cell population’s proliferative capabilities after injury, its ability to become neural cells in the post-injury environment, and tested various growth factors to attempt to recapitulate the cell population�...
Source: BioMed Central Blog - February 27, 2017 Category: Journals (General) Authors: Dana Berry Tags: Biology Health Medicine #moretoscience careers early career researchers PhD Science > Careers Source Type: blogs

Viewpoint Stroke prevention in recent guidelines for the management of patients with atrial fibrillation: An appraisal
Formal guidelines play an important role in disseminating the best available evidence knowledge and are expected to provide simple and practical recommendations for the most optimal management of patients with various conditions. Such guidelines have important implications for many disease states, which thereby could be more professionally managed in everyday clinical practice by clinicians with divergent educational backgrounds, and also more easily implemented in wards or outpatient clinics eliminating inequalities in health care management.
Source: The American Journal of Medicine - March 23, 2017 Category: Journals (General) Authors: Tatjana S. Potpara, Gregory Y.H. Lip, Carina Blomstr öm Lundqvist, Chern-En Chiang, A. John Camm Tags: Review Source Type: research

Viewpoint: Stroke Prevention in Recent Guidelines for the Management of Patients with Atrial Fibrillation: An Appraisal
Formal guidelines play an important role in disseminating the best available evidence knowledge and are expected to provide simple and practical recommendations for the most optimal management of patients with various conditions. Such guidelines have important implications for many disease states, which thereby could be more professionally managed in everyday clinical practice by clinicians with divergent educational backgrounds, and also more easily implemented in wards or outpatient clinics, eliminating inequalities in health care management.
Source: The American Journal of Medicine - March 23, 2017 Category: Journals (General) Authors: Tatjana S. Potpara, Gregory Y.H. Lip, Carina Blomstr öm-Lundqvist, Chern-En Chiang, A. John Camm Tags: Review Source Type: research

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