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Potential Use of Antioxidant Compounds for the Treatment of Inflammatory Bowel Disease
Pharmaceuticals (Basel). 2023 Aug 14;16(8):1150. doi: 10.3390/ph16081150.ABSTRACTSince inflammatory bowel diseases (IBDs) are chronic, the development of new effective therapeutics to combat them does not lose relevance. Oxidative stress is one of the main pathological processes that determines the progression of IBD. In this regard, antioxidant therapy seems to be a promising approach. The role of oxidative stress in the development and progression of IBD is considered in detail in this review. The main cause of oxidative stress in IBD is an inadequate response of leukocytes to dysbiosis and food components in the intesti...
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Alexander V Blagov Varvara A Orekhova Vasily N Sukhorukov Alexandra A Melnichenko Alexander N Orekhov Source Type: research

Tumor microenvironment remodeling in oral cancer: Application of plant derived-natural products and nanomaterials
Environ Res. 2023 Jun 16:116432. doi: 10.1016/j.envres.2023.116432. Online ahead of print.ABSTRACTOral cancers consist of squamous cell carcinoma (SCC) and other malignancies in the mouth with varying degrees of invasion and differentiation. For many years, different modalities such as surgery, radiation therapy, and classical chemotherapy drugs have been used to control the growth of oral tumors. Nowadays, studies have confirmed the remarkable effects of the tumor microenvironment (TME) on the development, invasion, and therapeutic resistance of tumors like oral cancers. Therefore, several studies have been conducted to m...
Source: Cancer Control - June 18, 2023 Category: Cancer & Oncology Authors: Hendrik Setia Budi Bagher Farhood Source Type: research

Role of Supplements in the Management of COVID-19 - A Comprehensive Review
Infect Disord Drug Targets. 2023 Mar 10. doi: 10.2174/1871526523666230310094646. Online ahead of print.ABSTRACTCoronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) and patients with COVID-19 may be treated primarily with SARS CoV-2-targeting drugs and the therapeutic agents assisting in the management of COVID-19 complications. This review focuses on the supplements like vitamins, minerals, herbal constituents, and others that help prevent or manage negative outcomes among COVID-19 patients. The literature was searched in databases such as Medline/PubMed Central/...
Source: Infectious Disorders Drug Targets - March 10, 2023 Category: Infectious Diseases Authors: Rajkapoor Balasubramanian Naina Mohamed Pakkir Maideen Sudha Muthusamy Sambathkumar Ramanathan Mohamed Harsath Jahir Hussain Source Type: research

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