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Drug: Melatonin
Nutrition: Sodium
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Total 68 results found since Jan 2013.
Melatonin Supplementation Reduces Nighttime Blood Pressure But Does Not Affect Blood Pressure Reactivity in Normotensive Adults on a High Sodium Diet
In conclusion, melatonin supplementation did not alter BP reactivity to the perturbations tested on a HSD but may be beneficial in lowering BP in young healthy normotensive adults.PMID:37642281 | DOI:10.1152/ajpregu.00101.2023
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - August 29, 2023 Category: Physiology Authors: Macarena Ramos Gonzalez Michael R Axler Kathryn E Kaseman Andrea J Lobene William B Farquhar Melissa A Witman Danielle L Kirkman Shannon L Lennon Source Type: research
Melatonin alleviated fluoride-induced impairment of spermatogenesis and sperm maturation process via Interleukin-17A
This study aims to explore whether MLT can mitigate fluoride-induced male reproductive toxicity through IL-17A, and screen the potential targets. So the wild type and IL-17A knockout mice were employed and treated with sodium fluoride (100 mg/L) by drinking water and MLT (10 mg/kg.BW, intraperitoneal injection per two days starting from week 16) for 18 weeks. Bone F- concentrations, grade of dental damage, sperm quality, spermatogenic cells counts, histological morphology of testis and epididymis, and the mRNA expression of spermatogenesis and maturation, classical pyroptosis related and immune factor genes were detected r...
Source: Food and Chemical Toxicology - June 3, 2023 Category: Food Science Authors: Huifeng Luo Rongxiu Liu Yilin Lang Jinhui Zhao Cuicui Zhuang Jundong Wang Chen Liang Jianhai Zhang Source Type: research
Maternal melatonin supplementation shapes gut microbiota and protects against inflammation in early life
CONCLUSION: This study suggests that maternal melatonin supplementation can shape the gut microbiota and metabolism of offspring under normal physiological conditions and protect them against LPS-induced inflammation in early life.PMID:37257272 | DOI:10.1016/j.intimp.2023.110359
Source: International Immunopharmacology - May 31, 2023 Category: Allergy & Immunology Authors: Fei Li Jiahao Lai Fei Ma Yao Cai Sitao Li Zhoushan Feng Zhendong Lu Xiao Liu Qiong Ke Hu Hao Xin Xiao Source Type: research
Effect of pharmacological stimulation of melatonin receptors on renal function in aging.
Adv Gerontol. 2023;36(1):68-75.ABSTRACTThe aim of the study was to study ion exchange, as well as water and nitrogen excretion function of the kidneys in rats under the influence of pharmacological stimulation of melatonin receptors. The experiment was conducted on male rats, which were divided into 2 groups. The first group was a control group (n=35) and was kept in standard vivarium conditions. Animals of the second group received melatonin along with drinking water throughout their lives (n=35). The study was conducted in compliance with the international principles of the Helsinki Declaration on Humane Treatment of Ani...
Source: Adv Data - May 16, 2023 Category: Epidemiology Authors: O V Zhukova I A Vinogradova A I Goransky Source Type: research
