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Specialty: General Medicine
Drug: Magnesium
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Total 171 results found since Jan 2013.
Efficacy and safety of drug therapy for the prevention and treatment of chemotherapy-induced peripheral neuropathy: a protocol for a systematic review and network meta-analysis
This article describes a protocol for evaluating the efficacy and safety of drug therapy for the prevention and treatment of CIPN. The results of the proposed systematic review with network meta-analysis (NMA) will provide new insights into the prevention and treatment of CIPN.
Methods and analysis
We will conduct a literature search in MEDLINE, PubMed, Embase, Cochrane Central Register of Controlled Trials and ClinicalTrials.gov to find relevant articles published through January 2023. We will include studies that investigated the efficacy and safety of vitamin B12, goshajinkigan, non-steroidal anti-inflammatory analgesi...
Source: BMJ Open - September 12, 2023 Category: General Medicine Authors: Sato, M. T., Hasegawa, T., Noma, H., Sugita, H., Ota, E. Tags: Open access, Oncology Source Type: research
The Pharmacologic Management of Cardiac Arrest
This article covers the current state of evidence for the effectiveness of the vasopressor epinephrine and the combination of vasopressin-steroids-epinephrine and antiarrhythmic medications amiodarone and lidocaine and reviews the role of other medications such as calcium, sodium bicarbonate, magnesium, and atropine in cardiac arrest care. We additionally review the role of β-blockers for refractory pulseless ventricular tachycardia/ventricular fibrillation and thrombolytics in undifferentiated cardiac arrest and suspected fatal pulmonary embolism.PMID:37391250 | DOI:10.1016/j.emc.2023.03.010
Source: The Medical Clinics of North America - June 30, 2023 Category: General Medicine Authors: Amandeep Singh Megan Heeney Martha E Montgomery Source Type: research
Interventions for the symptoms and signs resulting from jellyfish stings
CONCLUSIONS: Few studies contributed data to this review, and those that did contribute varied in types of treatment, settings, and range of jellyfish species. We are unsure of the effectiveness of any of the treatments evaluated in this review given the very low certainty of all the evidence. This updated review includes two new studies (with 139 additional participants). The findings are consistent with the previous review.PMID:37272501 | PMC:PMC10240560 | DOI:10.1002/14651858.CD009688.pub3
Source: Cochrane Database of Systematic Reviews - June 5, 2023 Category: General Medicine Authors: Richard G McGee Angela C Webster Sharon R Lewis Michelle Welsford Source Type: research
Pharmacological interventions for acute attacks of vestibular migraine
CONCLUSIONS: The evidence for interventions used to treat acute attacks of vestibular migraine is very sparse. We identified only two studies, both of which assessed the use of triptans. We rated all the evidence as very low-certainty, meaning that we have little confidence in the effect estimates and cannot be sure if triptans have any effect on the symptoms of vestibular migraine. Although we identified sparse information on potential harms of treatment in this review, the use of triptans for other conditions (such as headache migraine) is known to be associated with some adverse effects. We did not identify any placebo-...
Source: Cochrane Database of Systematic Reviews - April 12, 2023 Category: General Medicine Authors: Katie E Webster Afrose Dor Kevin Galbraith Luma Haj Kassem Natasha A Harrington-Benton Owen Judd Diego Kaski Otto R Maarsingh Samuel MacKeith Jaydip Ray Vincent A Van Vugt Martin J Burton Source Type: research
The National COVID-19 Clinical Evidence Taskforce: pregnancy and perinatal guidelines
Med J Aust. 2022 Oct 2. doi: 10.5694/mja2.51729. Online ahead of print.ABSTRACTINTRODUCTION: Pregnant women are at higher risk of severe illness from coronavirus disease 2019 (COVID-19) than non-pregnant women of a similar age. Early in the COVID-19 pandemic, it was clear that evidenced-based guidance was needed, and that it would need to be updated rapidly. The National COVID-19 Clinical Evidence Taskforce provided a resource to guide care for people with COVID-19, including during pregnancy. Care for pregnant and breastfeeding women and their babies was included as a priority when the Taskforce was set up, with a Pregnan...
Source: Med J Aust - October 2, 2022 Category: General Medicine Authors: Caroline Se Homer Vijay Roach Leila Cusack Michelle L Giles Clare Whitehead Wendy Burton Teena Downton Glenda Gleeson Adrienne Gordon Karen Hose Jenny Hunt Jackie Kitschke Nolan McDonnell Philippa Middleton Jeremy Jn Oats Antonia W Shand Kellie Wilton Jos Source Type: research
Evaluation and Management of Asthma and Chronic Obstructive Pulmonary Disease Exacerbation in the Emergency Department
Emerg Med Clin North Am. 2022 Aug;40(3):539-563. doi: 10.1016/j.emc.2022.05.007. Epub 2022 Jul 9.ABSTRACTObstructive lung disease includes asthma and chronic obstructive pulmonary disease (COPD). Exacerbation of asthma or COPD can result in significant morbidity and mortality, and emergency department (ED) care is often required. ED evaluation should assess risk factors for severe exacerbation and the patient's hemodynamic and respiratory status. Assessments including chest radiograph, point-of-care ultrasound, capnography, and electrocardiogram can assist. First-line treatments for acute exacerbation include bronchodilato...
Source: The Medical Clinics of North America - August 11, 2022 Category: General Medicine Authors: Brit Long Salim R Rezaie Source Type: research
Tocolytics for delaying preterm birth: a network meta-analysis (0924)
CONCLUSIONS: Compared with placebo or no tocolytic treatment, all tocolytic drug classes that we assessed (betamimetics, calcium channel blockers, magnesium sulphate, oxytocin receptor antagonists, nitric oxide donors) and their combinations were probably or possibly effective in delaying preterm birth for 48 hours, and 7 days. Tocolytic drugs were associated with a range of adverse effects (from minor to potentially severe) compared with placebo or no tocolytic treatment, although betamimetics and combination tocolytics were more likely to result in cessation of treatment. The effects of tocolytic use on neonatal outcomes...
Source: Cochrane Database of Systematic Reviews - August 10, 2022 Category: General Medicine Authors: Amie Wilson Victoria A Hodgetts-Morton Ella J Marson Alexandra D Markland Eva Larkai Argyro Papadopoulou Arri Coomarasamy Aurelio Tobias Doris Chou Olufemi T Oladapo Malcolm J Price Katie Morris Ioannis D Gallos Source Type: research
Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease
CONCLUSIONS: Intravenous magnesium sulfate may be associated with fewer hospital admissions, reduced length of hospital stay and improved dyspnoea scores compared to placebo. There is no evidence of a difference between magnesium infusion and placebo for NIV, lung function, oxygen saturation or adverse events. We found no evidence for ICU admission, endotracheal intubation, serious adverse events or mortality. For nebulised magnesium sulfate, we are unable to draw conclusions about its effects in COPD exacerbations for most of the outcomes. Studies reported possibly lower ICU admissions and a lesser degree of dyspnoea with...
Source: Cochrane Database of Systematic Reviews - May 26, 2022 Category: General Medicine Authors: Han Ni Swe Zin Aye Cho Naing Source Type: research
