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Drug: Insulin
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Total 153 results found since Jan 2013.
GLP-1 receptor agonists effect on cognitive function in patients with and without type 2 diabetes
Diabetes Metab. 2023 Aug 30:101470. doi: 10.1016/j.diabet.2023.101470. Online ahead of print.ABSTRACTGlucagon-like peptide 1 (GLP-1) is a hormone of the incretin family, secreted in response to nutrient ingestion, and plays a role in metabolic homeostasis. GLP-1 receptor agonist has a peripheral and a central action, including stimulation of glucose-dependent insulin secretion and insulin biosynthesis, inhibition of glucagon secretion and gastric emptying, and inhibition of food intake. Through their mechanism, their use in the treatment of type 2 diabetes has been extended to the management of obesity, and numerous trials...
Source: Diabetes and Metabolism - September 1, 2023 Category: Endocrinology Authors: Marine Monney Fran çois R Jornayvaz Karim Gariani Source Type: research
ER stress aggravates diaphragm weakness through activating PERK/JNK signaling in obesity hypoventilation syndrome
CONCLUSIONS: These data suggest that ectopic lipid deposition impairs the diaphragmatic function of people with obesity. Activation of PERK/JNK signaling is involved in the pathogenesis of lipotoxicity-induced diaphragm weakness in obesity hypoventilation syndrome.PMID:37475688 | DOI:10.1002/oby.23809
Source: Obesity - July 21, 2023 Category: Eating Disorders & Weight Management Authors: Xiaoxin Xiang Yanhua Zhu Xuya Pan Wei Xin Jianning Chen Weijian Tang Ruomi Guo Wu Yuan Xuemin He Li Zhou Zhitao Ren Siying Wen Heting Wang Yan Lu Shasha Li Tufeng Chen Yuqi Zhou Zulin Dou Mengyin Cai Xiaoyue Zhang Yanming Chen Guojun Shi Source Type: research
Dorsal striatal response to taste is modified by obesity and insulin resistance
CONCLUSIONS: These data support the hypothesis that insulin resistance and obesity contribute to aberrant responses to taste in the DS, which is only partially attenuated by weight loss. Aberrant responses to food exposure may be a barrier to weight loss.PMID:37475685 | DOI:10.1002/oby.23799
Source: Obesity - July 21, 2023 Category: Eating Disorders & Weight Management Authors: Julia P Dunn Bidhan Lamichhane Gordon I Smith Amy Garner Michael Wallendorf Tamara Hershey Samuel Klein Source Type: research
ER stress aggravates diaphragm weakness through activating PERK/JNK signaling in obesity hypoventilation syndrome
CONCLUSIONS: These data suggest that ectopic lipid deposition impairs the diaphragmatic function of people with obesity. Activation of PERK/JNK signaling is involved in the pathogenesis of lipotoxicity-induced diaphragm weakness in obesity hypoventilation syndrome.PMID:37475688 | DOI:10.1002/oby.23809
Source: Obesity - July 21, 2023 Category: Eating Disorders & Weight Management Authors: Xiaoxin Xiang Yanhua Zhu Xuya Pan Wei Xin Jianning Chen Weijian Tang Ruomi Guo Wu Yuan Xuemin He Li Zhou Zhitao Ren Siying Wen Heting Wang Yan Lu Shasha Li Tufeng Chen Yuqi Zhou Zulin Dou Mengyin Cai Xiaoyue Zhang Yanming Chen Guojun Shi Source Type: research
Dorsal striatal response to taste is modified by obesity and insulin resistance
CONCLUSIONS: These data support the hypothesis that insulin resistance and obesity contribute to aberrant responses to taste in the DS, which is only partially attenuated by weight loss. Aberrant responses to food exposure may be a barrier to weight loss.PMID:37475685 | DOI:10.1002/oby.23799
Source: Obesity - July 21, 2023 Category: Eating Disorders & Weight Management Authors: Julia P Dunn Bidhan Lamichhane Gordon I Smith Amy Garner Michael Wallendorf Tamara Hershey Samuel Klein Source Type: research
ER stress aggravates diaphragm weakness through activating PERK/JNK signaling in obesity hypoventilation syndrome
CONCLUSIONS: These data suggest that ectopic lipid deposition impairs the diaphragmatic function of people with obesity. Activation of PERK/JNK signaling is involved in the pathogenesis of lipotoxicity-induced diaphragm weakness in obesity hypoventilation syndrome.PMID:37475688 | DOI:10.1002/oby.23809
Source: Obesity - July 21, 2023 Category: Eating Disorders & Weight Management Authors: Xiaoxin Xiang Yanhua Zhu Xuya Pan Wei Xin Jianning Chen Weijian Tang Ruomi Guo Wu Yuan Xuemin He Li Zhou Zhitao Ren Siying Wen Heting Wang Yan Lu Shasha Li Tufeng Chen Yuqi Zhou Zulin Dou Mengyin Cai Xiaoyue Zhang Yanming Chen Guojun Shi Source Type: research
Dorsal striatal response to taste is modified by obesity and insulin resistance
CONCLUSIONS: These data support the hypothesis that insulin resistance and obesity contribute to aberrant responses to taste in the DS, which is only partially attenuated by weight loss. Aberrant responses to food exposure may be a barrier to weight loss.PMID:37475685 | DOI:10.1002/oby.23799
Source: Obesity - July 21, 2023 Category: Eating Disorders & Weight Management Authors: Julia P Dunn Bidhan Lamichhane Gordon I Smith Amy Garner Michael Wallendorf Tamara Hershey Samuel Klein Source Type: research
Effect of insulin resistance on left ventricular remodelling in essential hypertensives: a cross-sectional study
CONCLUSIONS: Insulin resistance and hyperinsulinaemia did not have the same influence on the components of Devereux's formula. Insulin resistance appeared to act on left ventricular end-diastolic diameter, while hyperinsulinaemia affected the posterior wall thickness. Both abnormalities acted on the interventricular septum and contributed to diastolic dysfunction via the E-wave deceleration time.PMID:37367993 | DOI:10.5830/CVJA-2023-024
Source: Cardiovascular Journal of Africa - June 27, 2023 Category: Cardiology Authors: Bernard Kianu Phanzu Aliocha Nkodila Natuhoyila Eleuth ère Kintoki Vita Benjamin Longo-Mbenza Jean-Ren é M'Buyamba Kabangu Source Type: research
Recent advancements in glucose dysregulation and pharmacological management of osteoporosis in transfusion-dependent thalassemia (TDT): an update of ICET-A (International Network of Clinicians for Endocrinopathies in Thalassemia and Adolescence Medicine)
CONCLUSIONS: Advances in the care of TDT patients have led to improved survival and quality of life. Nevertheless, many chronic endocrine complications still remain. Their routine screening and a high index of suspicion are imperative in order to provide timely diagnosis and treatment.PMID:37326257 | DOI:10.23750/abm.v94i3.14805
Source: Acta Bio-Medica : Atenei Parmensis - June 16, 2023 Category: General Medicine Authors: Ploutarchos Tzoulis Maria P Yavropoulou Atanas Banchev Iskra Modeva Shahina Daar Vincenzo De Sanctis Source Type: research
