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Nuts and seeds consumption and risk of cardiovascular disease, type 2 diabetes and their risk factors: a systematic review and meta-analysis
CONCLUSION: There is a probable relationship between consumption of nuts/seeds and lower risk of CVD, mostly driven by CHD, possibly in part through effects on blood lipids. More research on stroke and T2D may affect the conclusions. The evidence of specific nuts should be further investigated.PMID:36816545 | PMC:PMC9930735 | DOI:10.29219/fnr.v67.8961
Source: Atherosclerosis - February 23, 2023 Category: Cardiology Authors: Erik Kristoffer Arnesen Birna Thorisdottir Linnea B ärebring Fredrik S öderlund Bright I Nwaru Ulrike Spielau Jutta Dierkes Alfons Ramel Christel Lamberg-Allardt Agneta Åkesson Source Type: research

Novel biomarkers and emerging tools to identify causal molecular pathways in hypertension and associated cardiovascular diseases
Kardiol Pol. 2023 Feb 5. doi: 10.33963/KP.a2023.0037. Online ahead of print.ABSTRACTHypertension (HT) is a modifiable risk factor for life-threatening cardiovascular diseases (CVDs) including coronary artery disease, heart failure or stroke. Despite significant progress in understanding of the pathophysiological mechanisms of the disease, the molecular pathways targeted by HT treatment still remain largely unchanged. This warrants the necessity for searching novel biomarkers, which are causally related to persistent high blood pressure (BP) and may be pharmacologically targeted. Data from large-scale biobanks, containing h...
Source: Polish Heart Journal - February 5, 2023 Category: Cardiology Authors: Ewelina J ózefczuk Tomasz J Guzik Mateusz Siedlinski Source Type: research

Association of hyperuricemia with cardiovascular diseases: current evidence
Hosp Pract (1995). 2023 Feb 2. doi: 10.1080/21548331.2023.2173413. Online ahead of print.ABSTRACTThe aim of the present study is to present a historical and unified perspective on the association of serum uric acid (SUA) in the cause cardiovascular diseases (CVDs). The association of hyperuricemia (HUC) with CVD begun to be appreciated in the middle 1950s and early 1990s when clinical evidence was shown on the association of HUC with CVD. However, this association was disputed by several investigators including the Framingham group and by professional societies, like the American Heart Association and the American Society ...
Source: Atherosclerosis - February 2, 2023 Category: Cardiology Authors: Steven G Chrysant Source Type: research

Triglyceride-glucose index and the incidence of stroke: A meta-analysis of cohort studies
CONCLUSION: A higher TyG index may be independently associated with a higher risk of stroke in individuals without stroke at baseline. The aforementioned findings need to be verified by a large-scale prospective cohort study to further clarify the underlying pathophysiological mechanism between the TyG index and stroke.PMID:36686534 | PMC:PMC9845890 | DOI:10.3389/fneur.2022.1033385
Source: Atherosclerosis - January 23, 2023 Category: Cardiology Authors: Canlin Liao Haixiong Xu Tao Jin Ke Xu Zhennan Xu Lingzhen Zhu Mingfa Liu Source Type: research

Insulin resistance in ischemic stroke: Mechanisms and therapeutic approaches
Front Endocrinol (Lausanne). 2022 Dec 15;13:1092431. doi: 10.3389/fendo.2022.1092431. eCollection 2022.ABSTRACTThe pathological condition of insulin resistance prevents the neuroprotective effects of insulin. Numerous studies have demonstrated that insulin resistance, as an independent risk factor for ischemic stroke, accelerates the formation of thrombosis and promotes the development of atherosclerosis, both of which are major mechanisms of ischemic stroke. Additionally, insulin resistance negatively affects the prognosis of patients with ischemic stroke regardless of whether the patient has diabetes, but the mechanisms ...
Source: Atherosclerosis - January 2, 2023 Category: Cardiology Authors: Peng-Fei Ding Hua-Sheng Zhang Jie Wang Yong-Yue Gao Jian-Nan Mao Chun-Hua Hang Wei Li Source Type: research

Triglyceride-glucose index as a prognostic marker after ischemic stroke or transient ischemic attack: a prospective observational study
CONCLUSIONS: TyG index is associated with cervicocerebral atherosclerosis and the MACE risk after a stroke, suggesting the potential value of TyG index to optimize the risk stratification of stroke patients. Trial registration URL: https://upload.umin.ac.jp . Unique identifier: UMIN000031913.PMID:36451149 | DOI:10.1186/s12933-022-01695-2
Source: Atherosclerosis - November 30, 2022 Category: Cardiology Authors: Takao Hoshino Takafumi Mizuno Kentaro Ishizuka Shuntaro Takahashi Satoko Arai Sono Toi Kazuo Kitagawa Source Type: research

Dietary Meat, Trimethylamine N-Oxide-Related Metabolites, and Incident Cardiovascular Disease Among Older Adults: The Cardiovascular Health Study
CONCLUSIONS: In this large, community-based cohort, higher meat intake associated with incident ASCVD, partly mediated by microbiota-derived metabolites of L-carnitine, abundant in red meat. These novel findings support biochemical links between dietary meat, gut microbiome pathways, and ASCVD.PMID:35912635 | DOI:10.1161/ATVBAHA.121.316533
Source: Arteriosclerosis, Thrombosis and Vascular Biology - August 1, 2022 Category: Cardiology Authors: Meng Wang Zeneng Wang Yujin Lee Heidi T M Lai Marcia C de Oliveira Otto Rozenn N Lemaitre Amanda Fretts Nona Sotoodehnia Matthew Budoff Joseph A DiDonato Barbara McKnight W H Wilson Tang Bruce M Psaty David S Siscovick Stanley L Hazen Dariush Mozaffarian Source Type: research

Triglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study
It has been suggested that the baseline triglyceride-glucose (TyG) index, a simple surrogate measure for insulin resistance, is significantly associated with the occurrence of stroke. Nevertheless, the impact ...
Source: Cardiovascular Diabetology - July 27, 2022 Category: Cardiology Authors: Zegui Huang, Xiong Ding, Qing Yue, Xianxuan Wang, Zekai Chen, Zefeng Cai, Weijian Li, Zhiwei Cai, Guanzhi Chen, Yulong Lan, Weiqiang Wu, Shouling Wu and Youren Chen Tags: Research Source Type: research

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