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Effects of Catheter Tracking Management on Urinary Tract Function and Infection Rates in Patients With Spinal Cord Injury
CONCLUSIONS: For patients with SCIs, catheter follow-up management can be helpful in restoring the function of the bladder and urinary tract, can improve patients' QoL, and reduce their rate of UTIs. Clinically, medical practitioners should select antibiotics reasonably according to a bacterial culture and drug-sensitivity test.PMID:36634314
Source: Alternative Therapies in Health and Medicine - January 12, 2023 Category: Complementary Medicine Authors: Zhang Ruijuan Xiao Li Wang Yingjie Wang Rui Lu Chunqing Source Type: research

Progress of Research on the Application of Triple Antibiotic Paste and Hydrogel Scaffold Materials in Endodontic Revascularization: A Systematic Review
Conclusion. Hydrogels regulate stem cell fates, modulate growth factor release, and encapsulate antibacterial and anti-inflammatory drugs. The triple antibiotic paste is composed of metronidazole, ciprofloxacin, and minocycline, which exhibits promising antibacterial effects and duration at appropriate concentrations, with low cytotoxicity, and effectively promotes the preservation and regeneration of pulp tissues and the formation of dental hard tissues. However, issues such as tooth discoloration and bacterial drug resistance also exist. The present article reviews the progress of research on the application of hydrogel ...
Source: Evidence-based Complementary and Alternative Medicine - July 7, 2022 Category: Complementary Medicine Authors: Jia Zhao Source Type: research

< em > Carica papaya < /em > L. Leaf: A Systematic Scoping Review on Biological Safety and Herb-Drug Interactions
CONCLUSION: C. papaya leaf consumption in adults is generally safe for short-term use though cautioned in pregnancy and people with liver impairment. It has potential herb-drug interactions with oral hypoglycaemic agents, p-glycoprotein substrates, and antibiotics with cation chelating properties.PMID:34040647 | PMC:PMC8121580 | DOI:10.1155/2021/5511221
Source: Evidence-based Complementary and Alternative Medicine - May 27, 2021 Category: Complementary Medicine Authors: X Y Lim J S W Chan N Japri J C Lee T Y C Tan Source Type: research

Embelin-loaded chitosan gold nanoparticles interact synergistically with ciprofloxacin by inhibiting efflux pumps in multidrug-resistant Pseudomonas aeruginosa and Escherichia coli
Environ Res. 2021 May 11:111321. doi: 10.1016/j.envres.2021.111321. Online ahead of print.ABSTRACTA global upsurge in emergence and spread of antibiotic resistance (ABR) in bacterial populations is a serious threat for human health. Unfortunately, ABR is no longer confined to nosocomial environments and is frequently reported from community microbes as well. The ABR is resulting in shrinking potent antibiotics pool and thus necessitating novel and alternative therapies and therapeutics. Current investigation was aimed to assess the synergistic potential of a synthesized, phytomolecule-loaded, polysaccharide-stabilized meta...
Source: Environmental Research - May 14, 2021 Category: Environmental Health Authors: Tushar Khare Sneha Mahalunkar Varsha Shriram Suresh Gosavi Vinay Kumar Source Type: research

Ciprofloxacin and dexamethasone in combination attenuate S. aureus induced brain abscess via neuroendocrine-immune interaction of TLR-2 and glucocorticoid receptor leading to behavioral improvement
In this study, an attempt had been taken to utilize the functional relationship or cross-talking between TLR-2 and GR during the pathogenesis of brain abscesses. Here, the combination of an antibiotic (i.e. ciprofloxacin) and dexamethasone was used to regulate the brain inflammation either in TLR-2 or GR blocking condition. We were also interested to figure out the possible impact of alternative therapy on behavioral impairments. The results indicated that combination treatment during TLR-2 blockade significantly reduced the bacterial burden and abscess area score in the infected brain. However, marked improvements were ob...
Source: International Immunopharmacology - May 7, 2021 Category: Allergy & Immunology Authors: Rajen Dey Biswadev Bishayi Source Type: research

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