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Therapeutic strategies for COVID-19 patients: An update
Infect Disord Drug Targets. 2022 Mar 22. doi: 10.2174/1871526522666220322145729. Online ahead of print.ABSTRACTThe novel coronavirus SARS-coV-2, which emerged in Wuhan in November 2019, has increasingly spread causing a global pandemic that infected more than 444 million people, resulting in severe social and economic ramifications, and claimed more than 6,010,000 lives by March 5, 2022. The pandemic attracted global attention with consequential multiple economic, social, and clinical studies. Among causes of poor clinical outcome of the disease are therapeutic challenges, leading to spirals of studies in search for better...
Source: Infectious Disorders Drug Targets - March 23, 2022 Category: Infectious Diseases Authors: Muhammad Ibrahim Getso Soudabeh Etemadi Vahid Raissi Moein Mohseni Maedeh Sadat Mohseni Farid Raeisi Omid Raiesi Source Type: research

Counseling in maternal-fetal medicine: SARS-CoV-2 infection in pregnancy
This article is protected by copyright. All rights reserved.PMID:33724545 | DOI:10.1002/uog.23628
Source: The Ultrasound Review of Obstetrics and Gynecology - March 16, 2021 Category: Radiology Authors: D Di Mascio D Buca V Berghella A Khalil G Rizzo A Odibo G Saccone A Galindo M Liberati F D'Antonio Source Type: research

Perspectives on glucocorticoid treatment for COVID-19: a systematic review
This article aimed to review the studies that described the treatment with GC in COVID-19 patients. Randomized or nonrandomized clinical trials and retrospective or prospective-controlled longitudinal studies were screened for this systematic review. Studies in English, Portuguese, and Spanish published since 2019, with participants of any clinical status, geographic location, age, and sex were included. The most significant interest was related to the length of stay, radiological profile changes, viremia, and mortality. The research was done electronically on the Pubmed database using the following terms: "corticosteroids...
Source: Pharmacological Reports - March 5, 2021 Category: Drugs & Pharmacology Authors: Leonardo P Cordeiro Eduarda O N N Linhares Fernanda G O Nogueira Daniel Moreira-Silva Daniel J M Medeiros-Lima Source Type: research

A Decade of Anti-Myeloma Vaccine Development through Early Phase Trials: A Systematic Review
ConclusionAnti-myeloma vaccination therapy appears to be well tolerated, which makes it a promising adjuvant therapeutic agent against MM. Current data reveals positive immunologic activity in most patients and there is possibility of promising clinical responses with further drug development.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - November 21, 2018 Category: Hematology Authors: Nunes Cavalcante Parr, N. C., Tariq, M. J., Usman, M., Fraz, M. A., Khan, A. Y., Samuel, S., Ijaz, A., Ahmad, M. Q., Khalil, M. J., Yasir, M., Amin, S. N., Safdar, A., Rafae, A., Anwer, F. Tags: 653. Myeloma: Therapy, excluding Transplantation Source Type: research