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Drug: Dexamethasone
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Total 6433 results found since Jan 2013.
Pharmacotherapy for SARS-CoV-2 and Seizures for drug repurposing presumed on Mechanistic Targets
CONCLUSION: These findings would hopefully provide the basis for initiating further studies on the pathogenesis and drug targeting strategies for this emerging infection accompanied with seizures or in people with epilepsy.PMID:34645381 | DOI:10.2174/1874467214666211013122528
Source: Epilepsy Curr - October 14, 2021 Category: Neurology Authors: Divya Goel Ankit Srivastava Ángel Aledo-Serrano Anuja Krishnan Divya Vohora Source Type: research
Early ( & amp;lt; 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants
CONCLUSIONS: Early systemic postnatal corticosteroid treatment (started during the first six days after birth) prevents BPD and the combined outcome of mortality or BPD. However, it increases risks of gastrointestinal perforation, cerebral palsy, and the combined outcome of mortality or cerebral palsy. Most beneficial and harmful effects are related to early treatment with dexamethasone, rather than to early treatment with hydrocortisone, but early hydrocortisone may prevent mortality, whereas early dexamethasone does not. Longer-term follow-up into late childhood is vital for assessment of important outcomes that cannot b...
Source: Cochrane Database of Systematic Reviews - October 21, 2021 Category: General Medicine Authors: Lex W Doyle Jeanie L Cheong Susanne Hay Brett J Manley Henry L Halliday Source Type: research
Pharmacotherapy for SARS-CoV-2 and Seizures for drug repurposing presumed on Mechanistic Targets
CONCLUSION: These findings would hopefully provide the basis for initiating further studies on the pathogenesis and drug targeting strategies for this emerging infection accompanied with seizures or in people with epilepsy.PMID:34645381 | DOI:10.2174/1874467214666211013122528
Source: Epilepsy Curr - October 14, 2021 Category: Neurology Authors: Divya Goel Ankit Srivastava Ángel Aledo-Serrano Anuja Krishnan Divya Vohora Source Type: research
Late ( ≥ 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants
CONCLUSIONS: Late systemic postnatal corticosteroid treatment (started at seven days or more after birth) reduces the risks of mortality and BPD, and the combined outcome of mortality or BPD, without evidence of increased cerebral palsy. However, the methodological quality of studies determining long-term outcomes is limited, and no studies were powered to detect increased rates of important adverse long-term neurodevelopmental outcomes. This review supports the use of late systemic corticosteroids for infants who cannot be weaned from mechanical ventilation. The role of late systemic corticosteroids for infants who are no...
Source: Cochrane Database of Systematic Reviews - November 10, 2021 Category: General Medicine Authors: Lex W Doyle Jeanie L Cheong Susanne Hay Brett J Manley Henry L Halliday Source Type: research
Pepaxto: A New Peptide-Drug Conjugate for Heavily Pretreated Relapsed and Refractory Multiple Myeloma
CONCLUSIONS: The FDA approval of melflufen in combination with dexamethasone provides an additional therapy option for patients with heavily pretreated relapsed and refractory multiple myeloma.PMID:34963319 | DOI:10.1177/10600280211058388
Source: The Annals of Pharmacotherapy - December 29, 2021 Category: Drugs & Pharmacology Authors: Jeremiah K Jessee Source Type: research
Early pharmacological interventions for universal prevention of post-traumatic stress disorder (PTSD)
CONCLUSIONS: This review provides uncertain evidence only regarding the use of hydrocortisone, propranolol, dexamethasone, omega-3 fatty acids, gabapentin, paroxetine, PulmoCare formula, Oxepa formula, or 5-hydroxytryptophan as universal PTSD prevention strategies. Future research might benefit from larger samples, better reporting of side effects and inclusion of quality of life and functioning measures.PMID:35141873 | DOI:10.1002/14651858.CD013443.pub2
Source: Cochrane Database of Systematic Reviews - February 10, 2022 Category: General Medicine Authors: Federico Bertolini Lindsay Robertson Jonathan I Bisson Nicholas Meader Rachel Churchill Giovanni Ostuzzi Dan J Stein Taryn Williams Corrado Barbui Source Type: research
