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Drug: Dexamethasone
Nutrition: Vitamin A
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Total 138 results found since Jan 2013.
Corticosteroid implants for chronic non-infectious uveitis
CONCLUSIONS: Our confidence is limited that local corticosteroid implants are superior to sham therapy or standard-of-care therapy in reducing the risk of uveitis recurrence. We demonstrated different effectiveness on BCVA relative to comparators in people with non-infectious uveitis. Nevertheless, the evidence suggests that these implants may increase the risk of cataract progression and IOP elevation, which will require interventions over time. To better understand the efficacy and safety profiles of corticosteroid implants, we need future trials that examine implants of different doses, used for different durations. The...
Source: Cochrane Database of Systematic Reviews - August 29, 2023 Category: General Medicine Authors: Amit Reddy Su-Hsun Liu Christopher J Brady Pamela C Sieving Alan G Palestine Source Type: research
Changes in the uninjected contralateral eye after intravitreal brolucizumab for exudative age-related macular degeneration
CONCLUSIONS: Although contralateral retinal changes have been described for many other vascular endothelial growth factor inhibitors, there is little evidence for brolucizumab. We describe a repeated dose- and time-related effect on the uninjected eye in a case of nAMD.PMID:37424299 | DOI:10.1177/11206721231187429
Source: European Journal of Ophthalmology - July 10, 2023 Category: Opthalmology Authors: Paolo Mora Carlo Bellucci Lorenzo M Radice Francesca Manzotti Stefano Gandolfi Source Type: research
The efficacy of different anti-vascular endothelial growth factor agents, and dexamethasone implant therapy in patients with serous retinal detachment caused by Irvine-Gass syndrome
CONCLUSION: All intravitreal agents were effective in terms of visual results in the SRD patients; however, eyes treated with IVA and IVDI required fewer injections, as compared to the eyes treated with IVB and IVR. Furthermore, SRD entirely resolved in all eyes in the IVA group at the final follow-up visit.PMID:37408434 | DOI:10.1177/11206721231185909
Source: European Journal of Ophthalmology - July 6, 2023 Category: Opthalmology Authors: Bu ğra Karasu Enes Kesim Ali R ıza Cenk Celebi Source Type: research
A case of recurring acute exudative polymorphous vitelliform maculopathy successfully treated with intravitreal Ozurdex injection
CONCLUSION: Our case demonstrates clinical and imaging findings consistent with recurrence of AEPVM with CMO that has been successfully treated with Ozurdex®.PMID:37350018 | DOI:10.1177/11206721231178559
Source: European Journal of Ophthalmology - June 23, 2023 Category: Opthalmology Authors: Vaishali Lodhia Anthony G Robson Shaheeni Khoda Hanbin Lee Edward Hughes Source Type: research
Anterior chamber bleeding due to intravitreal dexamethasone implant sclerotomy without vitreous hemorrhage
CONCLUSION: Anterior Chamber bleeding is a possible complication of dexamethasone implant, that can be treated in a conservative way.PMID:37254464 | DOI:10.1177/11206721231178058
Source: European Journal of Ophthalmology - May 31, 2023 Category: Opthalmology Authors: Luca Landini Giacomo Boscia Giancarlo Sborgia Mariaoliva Grassi Rosa Buonamassa Pasquale Viggiano Giulia Bisceglia Giovanni Alessio Francesco Boscia Source Type: research
Effect of intralenticular dexamethasone implant: A case report
CONCLUSIONS: The therapeutic effect of DEX implant can be maintained for a longer period of time than intravitreal implant, determining complete reabsorption of macular oedema. Intralenticular implant can be maintained inside the lens until either IOP increases, cataract progresses, or other complications occur.PMID:37165519 | DOI:10.1177/11206721231174934
Source: European Journal of Ophthalmology - May 11, 2023 Category: Opthalmology Authors: Adriano Carnevali Andrea Taloni Valentina Gatti Luca Lamonica Flavia Oliverio Giorgio Randazzo Vincenzo Scorcia Source Type: research
Senescence-induced alteration of circadian phagocytic activity of retinal pigment epithelium cell line ARPE-19
In this study, we used the human RPE cell line ARPE-19 to investigate whether hydrogen peroxide (H2O2)-induced senescence in ARPE-19 cells alters the circadian rhythm of their phagocytic activity. After synchronization of the cellular circadian clock by dexamethasone treatment, the phagocytic activity of normal ARPE-19 cells exhibited significant 24-h oscillation, but this oscillation was modulated by senescence. The phagocytic activity of senescent ARPE-19 cells increased constantly throughout the 24-h period, which still exhibited blunted circadian oscillation, accompanied by an alteration in the rhythmic expression of c...
Source: Biochemical and Biophysical Research communications - April 7, 2023 Category: Biochemistry Authors: Ken-Ichi Hashikawa Akito Tsuruta Wakaba Yamakawa Sai Yasukochi Satoru Koyanagi Shigehiro Ohdo Source Type: research
