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FGF-23 and sclerostin in serum and bone of CKD patients
CONCLUSION: These data show a progressive increase in FGF-23 and sclerostin in blood and bone associated with decrease in kidney function. The observed relationships between bone turnover and sclerostin or FGF-23 should be considered when treatment modalities are developed for management of turnover abnormalities in CKD patients.PMID:36970967 | DOI:10.5414/CN111111
Source: Clinical Nephrology - March 27, 2023 Category: Urology & Nephrology Authors: Florence Lima Marie-Claude Monier-Faugere Hanna Mawad Valentin David Hartmut H Malluche Source Type: research

Major Traditional Probiotics: Comparative Genomic Analyses and Roles in Gut Microbiome of Eight Cohorts
This study provides conceptual advances that lays the foundation for future applications in personalized probiotics, which must consider both the species/strain heterogeneity and individual heterogeneity. Author Contributions GH and GL designed the study. GL, BL, CY, YW, XB, WL, and FL performed the experiments and analyzed the data. GL wrote the manuscript. Funding This research was supported by the National Key R&D Program of China (Grant No. 2017YFD0400303). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that cou...
Source: Frontiers in Microbiology - April 8, 2019 Category: Microbiology Source Type: research