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Comparison of cumulative live birth rates between progestin and GnRH analogues in preimplantation genetic testing cycles
CONCLUSIONS: PPOS regimen may be adversely affect cumulative LBR and blastocyst quality in women with good prognosis compared to GnRH analogues in PGT cycles.PMID:37450562 | DOI:10.1210/clinem/dgad397
Source: The Journal of Clinical Endocrinology and Metabolism - July 14, 2023 Category: Endocrinology Authors: Ruiqiong Zhou Mei Dong Li Huang Songlu Wang Zhaoyi Wang Liqing Xu Xiqian Zhang Fenghua Liu Source Type: research

Unique transcriptomic changes underlie hormonal interactions during mammary histomorphogenesis in female pigs
Endocrinology. 2021 Dec 16:bqab256. doi: 10.1210/endocr/bqab256. Online ahead of print.ABSTRACTSuccessful lactation and the risk for developing breast cancer depend on growth and differentiation of the mammary gland (MG) epithelium that is regulated by ovarian steroids (17beta-estradiol [E] and progesterone [P]) and pituitary-derived prolactin (PRL). Given that the MG of pigs share histomorphogenic features present in the normal human breast, we sought to define the transcriptional responses within the MG of pigs following exposure to all combinations of these hormones. Hormone-ablated female pigs were administered combina...
Source: Endocrinology - December 17, 2021 Category: Endocrinology Authors: Josephine F Trott Anke Schennink Katherine C Horigan Danielle G Lemay Julia R Cohen Thomas R Famula Julie A Dragon Russell C Hovey Source Type: research

Melatonin attenuates glucocorticoid effect induced by medroxyprogesterone acetate in rats
Gen Comp Endocrinol. 2021 Dec 1;316:113959. doi: 10.1016/j.ygcen.2021.113959. Online ahead of print.ABSTRACTMedroxyprogesterone acetate (MPA) acts on glucocorticoid receptors and, when it is in excess, can cause clinical disorders comparable to hyperadrenocorticism. Melatonin (MEL) is a hormone with potent antioxidant and anti-glucocorticoid activity and it can be beneficial in the excessive activation of glucocorticoid receptors. To evaluate the protective effects of MEL on the glucocorticoid effect of MPA, 34 male Wistar rats were randomized into four groups: CON (control), MEL, MPA, and MPA + MEL. The animals were treat...
Source: General and Comparative Endocrinology - December 3, 2021 Category: Endocrinology Authors: Mariana Moreira Andraschko Mara Ta ís de Carvalho Hugo Cardoso Martins Pires Hellen Dorneles de Deus Carla Mart í Castelló Liliana Borges de Menezes Danieli Brolo Martins Marina Pacheco Miguel Source Type: research

Regulation of maternal behavior, social isolation responses, and postpartum estrus by steroid hormones and vaginocervical stimulation in sheep
Conclusion: some hormonal treatments +VCS can effectively induce maternal behavior and reduce social isolation responses. Long-term progestin treatment can inhibit postpartum estrus.PMID:34560419 | DOI:10.1016/j.yhbeh.2021.105061
Source: Hormones and Behavior - September 24, 2021 Category: Endocrinology Authors: Rosalba Soto Ang élica Terrazas Pascal Poindron Gabriela Gonz ález-Mariscal Source Type: research

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