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Specialty: Neurology
Drug: Phenobarbital

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Total 123 results found since Jan 2013.

Increased risk of stroke and myocardial infarction in patients with epilepsy: A systematic review of population-based cohort studies.
CONCLUSIONS: Patients with epilepsy are at higher risk of subsequent stroke and MI in comparison with subjects without epilepsy. Although individual AEDs may carry different risks of cardio- and cerebrovascular disease, the clinical relevance of the metabolic effects of the enzyme-inducing AEDs is still uncertain. This article is part of the Special Issue "Seizures & Stroke. PMID: 31182394 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - June 6, 2019 Category: Neurology Authors: Brigo F, Lochner P, Nardone R, Manganotti P, Lattanzi S Tags: Epilepsy Behav Source Type: research

Increased risk of stroke and myocardial infarction in patients with epilepsy: A systematic review of population-based cohort studies
ConclusionsPatients with epilepsy are at higher risk of subsequent stroke and MI in comparison with subjects without epilepsy. Although individual AEDs may carry different risks of cardio- and cerebrovascular disease, the clinical relevance of the metabolic effects of the enzyme-inducing AEDs is still uncertain.This article is part of the Special Issue “Seizures & Stroke
Source: Epilepsy and Behavior - June 8, 2019 Category: Neurology Source Type: research

Stroke and Ischemic Heart Disease With Enzyme-inducing Antiseizure Medications: Time to Change Prescribing Habits
Conclusions and Relevance: The hazard of incident cardiovascular disease is higher in those receiving eiASMs. The association is dose dependent and the absolute difference in hazard seems to reach clinical significance by approximately 10 years from first exposure.PMID:35444497 | PMC:PMC8988723 | DOI:10.1177/15357597211070392
Source: Epilepsy Curr - April 21, 2022 Category: Neurology Authors: David G Vossler Source Type: research