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Specialty: Neurology
Drug: Phenytoin

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Total 843 results found since Jan 2013.

Unveiling the Anti-Convulsant Potential of Novel Series of 1,2,4-Triazine-6H-Indolo2,3-bquinoline Derivatives: In Silico Molecular Docking, ADMET, DFT, and Molecular Dynamics Exploration
CONCLUSION: Based on computational modelling techniques, an array of 1,2,4-Triazine-6H-indolo[2,3-b]quinoline derivatives were evaluated for their anti-convulsant properties. A stable compound within the GABAA receptor was identified by HRSN24, suggesting its affinity as an anti-convulsant.PMID:37592789 | DOI:10.2174/1573409920666230817144710
Source: Epilepsy Curr - August 18, 2023 Category: Neurology Authors: Hariram Singh Devender Pathak Source Type: research

A novel approach to seizures in neonates
Eur J Paediatr Neurol. 2023 Jul 27;46:89-97. doi: 10.1016/j.ejpn.2023.07.006. Online ahead of print.ABSTRACTTHE CHALLENGE OF SEIZURE RECOGNITION: Recognition of seizures in neonates remains the foremost challenge to overcome. All neonates at risk for seizures, especially the critically ill, should undergo video-EEG monitoring. The initial step toward an accurate diagnosis is the accurate description and interpretation of the electro-clinical phenotype. THE IMPORTANCE OF SEIZURE SEMIOLOGY AND ASSOCIATION WITH ETIOLOGY: The early distinction between acute provoked seizures and neonatal-onset epilepsies serves as the primary ...
Source: European Journal of Paediatric Neurology - August 6, 2023 Category: Neurology Authors: Evelina Carapancea Maria Roberta Cilio Source Type: research

Retraction notice to "Molecular mechanisms of neuroprotective effect of adjuvant therapy with phenytoin in pentylenetetrazole-induced seizures: Impact on Sirt1/NRF2 signaling pathways" Neurotoxicology 68 (2018) 47-65
Neurotoxicology. 2023 Jun 13:S0161-813X(23)00080-3. doi: 10.1016/j.neuro.2023.06.001. Online ahead of print.NO ABSTRACTPMID:37316402 | DOI:10.1016/j.neuro.2023.06.001
Source: Neurotoxicology - June 14, 2023 Category: Neurology Authors: Marwa M Nagib Mariane G Tadros Hadwa Ali Abd Al-Khalek Rania M Rahmo Nagwa Ali Sabri Amani E Khalifa Somaia I Masoud Source Type: research