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ST Elevations in the Setting of Hyperkalemia
A woman in her 50s with a history of hypertension, hyperlipidemia, diabetes, neuropathy, smoking, asthma, and previous stroke presented with altered mental status and respiratory distress necessitating intubation in the field. An electrocardiogram (ECG) was recorded on presentation (Figure 1). On arrival, she was found to have 1 episode of nonsustained ventricular tachycardia but otherwise remained in normal sinus rhythm. Home medications included lisinopril, amitriptyline hydrochloride, and insulin. On physical examination, she was nonresponsive, with blood pressure of 113/70 mm Hg and pulse of 59 beats per minute with 10...
Source: JAMA Internal Medicine - November 13, 2017 Category: Internal Medicine Source Type: research

Electrocardiographic Left Ventricular Hypertrophy Predicts Cardiovascular Morbidity and Mortality in Hypertensive Patients: The ALLHAT Study.
CONCLUSIONS: Baseline Cornell voltage LVH is associated with increased CV morbidity and all-cause mortality in treated hypertensive patients independent of treatment modality and other CV risk factors. CLINICAL TRIALS REGISTRATION: Trial Number NCT00000542. PMID: 28430947 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - April 19, 2017 Category: Cardiology Authors: Bang CN, Soliman EZ, Simpson LM, Davis BR, Devereux RB, Okin PM, and for the ALLHAT Collaborative Research Group Tags: Am J Hypertens Source Type: research

A Case of Transient Global Amnesia: A Review and How It May Shed Further Insight into the Neurobiology of Delusions
Conclusion In closing, our patient’s episode of TGA combined with her emotional and perceptual response lends credence to the proposal of a “fear/paranoia” circuit in the genesis of paranoid delusions—a circuit incorporating amygdala, frontal, and parietal cortices. Here, neutral or irrelevant stimuli, thoughts, and percepts come to engender fear and anxiety, while dysfunction in frontoparietal circuitry engenders inappropriate social predictions and maladaptive inferences about the intentions of others.[54] Hippocampus relays information about contextual information based on past experiences and the current situat...
Source: Innovations in Clinical Neuroscience - April 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Behavioral and Cognitive Neurology Case Report Cognition Current Issue Dementia Medical Issues Neurologic Systems and Symptoms Psychiatry Schizophrenia delusions hippocampus neurobiology Transient global amnesia Source Type: research

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