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Specialty: Reproduction Medicine
Drug: Estradiol
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Total 396 results found since Jan 2013.
Interaction of pre and postnatal nutrition on expression of leptin receptor variants and transporter molecules, leptin transport, and functional response to leptin in heifers †
Biol Reprod. 2023 Sep 12:ioad118. doi: 10.1093/biolre/ioad118. Online ahead of print.ABSTRACTPerinatal nutrition modulates the hypothalamic neurocircuitries controlling GnRH release, thus programming pubertal maturation in female mammals. Objectives of experiments reported here were to test the hypotheses that prenatal nutrition during mid- to late gestation interacts with postnatal nutrition during the juvenile period in heifer offspring to alter expression of leptin receptor (LepR) variants (ObRa, ObRb, ObRc, ObRt), and lipoprotein transporter molecules (LRP1 and 2) in the choroid plexus, leptin transport across the bloo...
Source: Biology of Reproduction - September 12, 2023 Category: Reproduction Medicine Authors: Gary L Williams Youwen Zhang Meaghan M O'Neil Tatiane S Maia Sarah M West Bruna R C Alves Viviana Garza Thomas H Welsh Rodolfo C Cardoso Source Type: research
Spexin role in human granulosa cells physiology and PCOS: expression and negative impact on steroidogenesis and proliferation
Biol Reprod. 2023 Sep 2:ioad108. doi: 10.1093/biolre/ioad108. Online ahead of print.ABSTRACTSpexin (SPX) is a novel neuropeptide and adipokine negatively correlated with obesity and insulin resistance. A recent study investigated expression and regulatory function of SPX in the hypothalamus and pituitary; however, the effect on ovarian function is still unknown. The aim of this study was to characterize the expression of SPX and its receptors, galanin receptors 2 and 3 (GALR2/3) in the human ovary and to study its in vitro effect on granulosa cells (GC) function. Follicular fluid (FF) and GC were obtained from normal weigh...
Source: Reproductive Biology - September 2, 2023 Category: Reproduction Medicine Authors: Patrycja Kurowska Monika Dawid Julia Oprocha Natalia Repekta Lo ïse Serra Anthony Estienne Piotr Pawlicki Ma łgorzata Kotula-Balak Fabrice Gu érif Joelle Dupont Agnieszka Rak Source Type: research
Low serum progesterone on day of transfer adversely impacts ongoing pregnancy rates in hormonally prepared single blastocyst frozen embryo transfer cycles
CONCLUSION: This study found that serum P level on the day of transfer in hormonally prepared FET cycles was a significant predictor of OPR.PMID:37639815 | DOI:10.1016/j.ejogrb.2023.08.016
Source: Reproductive Biology - August 28, 2023 Category: Reproduction Medicine Authors: Bhawani Shekhar Shweta Mittal Gaurav Majumdar Neeti Tiwari Abha Majumdar Source Type: research
The impact of non-caloric artificial sweetener aspartame on female reproductive system in mice model
CONCLUSION: Non-nutritive artificial sweeteners including aspartame negatively impact the function of ovaries and feedback mechanism of reproductive hormones by affecting the hypothalamic-pituitary-gonadal axis. In light of present findings the aspartame negatively impacted the reproductive system of female mice. More studies are required to identify the molecular mechanism and the pathways involved.PMID:37580716 | DOI:10.1186/s12958-023-01115-4
Source: Reproductive Biology - August 14, 2023 Category: Reproduction Medicine Authors: Ab Qayoom Naik Tabassum Zafar Vinoy K Shrivastava Source Type: research
The effects of human amnion membrane-derived mesenchymal stem cells conditioned medium on ionizing radiation-induced premature ovarian failure and endoplasmic reticulum stress-related apoptosis mechanism
CONCLUSION: The application of hAMSCs-CM has been found to have a positive impact on follicles affected by radiation. After treatment, the number of primordial, primary, secondary, and graafian follicles, which had previously decreased due to radiation, showed an increase. Furthermore, the number of atretic follicles, which had been increasing due to radiation, showed a decrease. ER is one of the targets affected by ionizing radiation. After ionizing radiation, the expressions of ER stress-related markers and apoptosis markers increased in the ovary. After hAMSCs-CM administration, the expressions of these markers and numb...
Source: Reproductive Biology - August 11, 2023 Category: Reproduction Medicine Authors: Burak Un Busra Cetinkaya-Un Meryem Akpolat Fundagul Andic Yusufhan Yazir Source Type: research
Risk factors for low oocyte retrieval in patients with polycystic ovarian syndrome undergoing in vitro fertilization
CONCLUSIONS: For patients with PCOS, low estradiol levels/follicles (≥ 12 mm) and progesterone levels on the trigger day and the use of the progestin-primed protocol could be risk factors for low ORR, which leads to a limited number of embryos and more cycle cancellations.PMID:37468927 | DOI:10.1186/s12958-023-01118-1
Source: Reproductive Biology - July 19, 2023 Category: Reproduction Medicine Authors: Hao Jin Haiyan Yang Jiujia Zheng Jiechun Zhou Rong Yu Source Type: research
Comparison of the duration of estradiol administration and the effect on pregnancy outcome of day 3 vitrified-warmed embryo transfer cycle: a randomized controlled trial
Zygote. 2023 Jul 14:1-7. doi: 10.1017/S096719942300031X. Online ahead of print.ABSTRACTBased on the fact that the follicular phase in the menstrual cycle has length variation, it has been assumed that the duration of oestrogen (E2) administration could also be variable; therefore, for the first time, this randomized clinical trial study was conducted to investigate and compare the duration of estradiol administration and the effect on pregnancy outcomes in the cleavage-stage frozen embryo transfer (FET) cycle. We included women aged 20-40 with a normal uterus on hysteroscopy between September and December 2022 and who were...
Source: Zygote - July 14, 2023 Category: Reproduction Medicine Authors: Afsoon Zarei Ameneh Keshavarzi Maryam Zare Source Type: research
